(77 nodes) Extracellular matrix organization network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_016664	Fasciclin domain-containing protein. (602 aa)
	APZ42_030563	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (803 aa)
	EOG090X0BWK	CDP-diacylglycerol--inositol 3-phosphatidyltransferase. (216 aa)
	APZ42_032797	Putative Cuticular protein. (116 aa)
	APZ42_023130	Putative Cuticular protein. (193 aa)
	APZ42_016667	Transforming growth factor-beta-induced protein ig-h3. (578 aa)
	APZ42_019897	Transforming growth factor-beta-induced protein. (851 aa)
	APZ42_022687	Dual specificity mitogen-activated protein kinase kinase. (803 aa)
	APZ42_011584	A disintegrin and metalloproteinase with thrombospondin motifs 8. (1286 aa)
	APZ42_013136	Uncharacterized protein. (328 aa)
	APZ42_022892	Uncharacterized protein. (282 aa)
	APZ42_018911	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1663 aa)
	APZ42_010335	FAS1 domain-containing protein. (86 aa)
	APZ42_029557	Putative Collagen alpha-1(XXV) chain. (1782 aa)
	APZ42_031255	FAS1 domain-containing protein. (162 aa)
	APZ42_004018	FAS1 domain-containing protein. (244 aa)
	APZ42_015862	Putative ADAMTS protein 3. (275 aa)
	APZ42_015857	Putative ADAMTS protein 3. (629 aa)
	APZ42_015022	Collagen alpha-1(XXIII) chain. (490 aa)
	APZ42_014782	Uncharacterized protein. (295 aa)
	APZ42_014243	Uncharacterized protein. (1261 aa)
	APZ42_013363	Uncharacterized protein. (687 aa)
	APZ42_013138	Uncharacterized protein. (303 aa)
	APZ42_013262	Uncharacterized protein. (304 aa)
	APZ42_012357	UDP-N-acetylhexosamine pyrophosphorylase 1-like protein. (525 aa)
	APZ42_012091	Putative EH domain-binding protein 1. (865 aa)
	APZ42_028390	Glucose-fructose oxidoreductase domain-containing protein 1. (398 aa)
	APZ42_016272	Putative Dynamin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (523 aa)
	APZ42_016907	A disintegrin and metalloproteinase with thrombospondin motifs 8. (1679 aa)
	APZ42_016793	Laminin subunit beta-1. (3675 aa)
	APZ42_017575	Uncharacterized protein. (419 aa)
	APZ42_018090	Multiplexin. (1307 aa)
	APZ42_018513	Putative Cuticular protein. (271 aa)
	APZ42_018551	Putative Stall. (804 aa)
	APZ42_019193	Putative A disintegrin and metalloproteinase with thrombospondin motifs 3. (702 aa)
	APZ42_011273	Laminin subunit gamma-3. (1735 aa)
	APZ42_011275	Putative Transforming growth factor-beta-induced protein Ig-H3. (593 aa)
	APZ42_011395	GAS2 1-like protein. (476 aa)
	APZ42_011590	DnaJ subfamily C member 22. (353 aa)
	APZ42_004848	Putative ADAMTS protein 3. (151 aa)
	APZ42_002627	ADAMTS protein 3. (113 aa)
	APZ42_034351	Uncharacterized protein. (584 aa)
	APZ42_034370	Female sterile M3. (2029 aa)
	APZ42_019844	Secreted protein acidic and rich in cysteine. (286 aa)
	APZ42_021128	Cadherin 99C. (1605 aa)
	APZ42_022191	Putative Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2. (610 aa)
	APZ42_022184	No long nerve cord, isoform C. (1807 aa)
	APZ42_022686	Dynamin. (531 aa)
	APZ42_022951	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (207 aa)
	APZ42_023119	Putative Ccp84Ae. (648 aa)
	APZ42_024156	Uncharacterized protein. (273 aa)
	APZ42_024600	Peroxidasin. (1075 aa)
	APZ42_027243	Uncharacterized protein. (1978 aa)
	APZ42_028343	Collagen alpha-2 chain. (1020 aa)
	APZ42_028279	Laminin subunit beta-1. (1611 aa)
	APZ42_028759	Putative Complement C1q tumor necrosis factor-related protein 2. (350 aa)
	APZ42_028565	Phosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family. (2115 aa)
	APZ42_028848	Fasciclin-1. (347 aa)
	APZ42_029556	Viking. (1766 aa)
	APZ42_029493	c-Myc promoter-binding protein. (1859 aa)
	APZ42_029677	Transforming growth factor-beta-induced protein Ig-H3. (664 aa)
	APZ42_030840	Putative A disintegrin and metalloproteinase with thrombospondin motifs 2. (839 aa)
	APZ42_030847	Putative A disintegrin and metalloproteinase with thrombospondin motifs 2. (759 aa)
	APZ42_031765	Putative Fasciclin-1. (1731 aa)
	APZ42_033286	Protein transport protein Sec24C. (1058 aa)
	APZ42_033645	Uncharacterized protein. (306 aa)
	APZ42_033646	FAS1 domain-containing protein. (137 aa)
	APZ42_033737	Reversion-inducing cysteine-rich protein with Kazal motifs. (845 aa)
	APZ42_034132	Matrix metalloproteinase-24. (652 aa)
	APZ42_034311	Putative SPARC-related modular calcium-binding protein 1. (363 aa)
	APZ42_018512	Cuticular protein. (141 aa)
	APZ42_013793	Nidogen-1. (1370 aa)
	APZ42_022326	Kazal-type serine protease inhibitor domain-containing protein 1. (321 aa)
	APZ42_020901	Cathepsin o. (303 aa)
	APZ42_014751	Topoisomerase II-associated PAT1 domain-containing protein. (408 aa)
	APZ42_033984	A disintegrin and metalloproteinase with thrombospondin motifs 6. (749 aa)
	APZ42_013191	Guanine nucleotide exchange factor MSS4. (114 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_011273	APZ42_013793	A0A162SJ87	A0A0P4YNS9	Laminin subunit gamma-3.	Nidogen-1.	0.871
APZ42_011273	APZ42_015022	A0A162SJ87	A0A162P4A1	Laminin subunit gamma-3.	Collagen alpha-1(XXIII) chain.	0.611
APZ42_011273	APZ42_016793	A0A162SJ87	A0A165A6B3	Laminin subunit gamma-3.	Laminin subunit beta-1.	0.994
APZ42_011273	APZ42_028279	A0A162SJ87	A0A164QNN0	Laminin subunit gamma-3.	Laminin subunit beta-1.	0.999
APZ42_011273	APZ42_028343	A0A162SJ87	A0A164QRG7	Laminin subunit gamma-3.	Collagen alpha-2 chain.	0.645
APZ42_011273	APZ42_029556	A0A162SJ87	A0A164PPS0	Laminin subunit gamma-3.	Viking.	0.645
APZ42_011273	APZ42_029557	A0A162SJ87	A0A162D540	Laminin subunit gamma-3.	Putative Collagen alpha-1(XXV) chain.	0.645
APZ42_011395	APZ42_018911	A0A162SN11	A0A162CQ61	GAS2 1-like protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.588
APZ42_012091	APZ42_022951	A0A162S2M8	A0A164VB60	Putative EH domain-binding protein 1.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.454
APZ42_012091	APZ42_027243	A0A162S2M8	A0A164RFG9	Putative EH domain-binding protein 1.	Uncharacterized protein.	0.535
APZ42_012357	APZ42_030563	A0A162RWK7	A0A0P5E3T1	UDP-N-acetylhexosamine pyrophosphorylase 1-like protein.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.567
APZ42_013136	APZ42_028848	A0A0P6ATS9	A0A164Q4P7	Uncharacterized protein.	Fasciclin-1.	0.525
APZ42_013138	APZ42_028848	A0A162R1T5	A0A164Q4P7	Uncharacterized protein.	Fasciclin-1.	0.526
APZ42_013191	APZ42_018911	A0A0P5DW36	A0A162CQ61	Guanine nucleotide exchange factor MSS4.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.529
APZ42_013191	APZ42_030563	A0A0P5DW36	A0A0P5E3T1	Guanine nucleotide exchange factor MSS4.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.529
APZ42_013262	APZ42_028848	A0A162R597	A0A164Q4P7	Uncharacterized protein.	Fasciclin-1.	0.528
APZ42_013793	APZ42_011273	A0A0P4YNS9	A0A162SJ87	Nidogen-1.	Laminin subunit gamma-3.	0.871
APZ42_013793	APZ42_016793	A0A0P4YNS9	A0A165A6B3	Nidogen-1.	Laminin subunit beta-1.	0.753
APZ42_013793	APZ42_018090	A0A0P4YNS9	A0A164ZBN0	Nidogen-1.	Multiplexin.	0.549
APZ42_013793	APZ42_019844	A0A0P4YNS9	A0A164XT76	Nidogen-1.	Secreted protein acidic and rich in cysteine.	0.607