(16 nodes) Negative regulation of histone modification network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_016994	PIH1 domain-containing protein 1. (208 aa)
	APZ42_016706	Putative Histone-lysine N-methyltransferase. (1974 aa)
	APZ42_030693	Autophagy protein 5; Involved in autophagic vesicle formation. (71 aa)
	APZ42_034215	Uncharacterized protein. (222 aa)
	APZ42_012143	JmjC domain-containing Histone demethylation protein 1. (874 aa)
	APZ42_014111	E3 ubiquitin-protein ligase hyd. (2906 aa)
	APZ42_015255	Lysine-specific demethylase 6A. (1264 aa)
	APZ42_017723	E3 ubiquitin-protein ligase TRIP12. (2249 aa)
	APZ42_016096	Protein FRG1. (266 aa)
	APZ42_028349	REST corepressor 3. (474 aa)
	APZ42_022979	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1390 aa)
	APZ42_012709	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (540 aa)
	APZ42_013624	Nucleolar complex protein 2. (821 aa)
	APZ42_033283	Alpha-aminoadipic semialdehyde synthase, mitochondrial. (952 aa)
	EOG090X0BB3	Autophagy protein 5; Involved in autophagic vesicle formation. (271 aa)
	APZ42_031507	Breast and ovarian cancer sususceptibility protein. (952 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_012143	APZ42_012709	A0A162S5W6	A0A0P5V584	JmjC domain-containing Histone demethylation protein 1.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.421
APZ42_012709	APZ42_012143	A0A0P5V584	A0A162S5W6	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	JmjC domain-containing Histone demethylation protein 1.	0.421
APZ42_012709	APZ42_022979	A0A0P5V584	A0A0P5ZVV5	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.810
APZ42_012709	APZ42_028349	A0A0P5V584	A0A0N8ATZ6	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	REST corepressor 3.	0.933
APZ42_014111	APZ42_016706	A0A162Q010	A0A165A3R1	E3 ubiquitin-protein ligase hyd.	Putative Histone-lysine N-methyltransferase.	0.530
APZ42_014111	APZ42_017723	A0A162Q010	A0A162CJF2	E3 ubiquitin-protein ligase hyd.	E3 ubiquitin-protein ligase TRIP12.	0.674
APZ42_015255	APZ42_016994	A0A162PCA2	A0A165AAA8	Lysine-specific demethylase 6A.	PIH1 domain-containing protein 1.	0.484
APZ42_016706	APZ42_014111	A0A165A3R1	A0A162Q010	Putative Histone-lysine N-methyltransferase.	E3 ubiquitin-protein ligase hyd.	0.530
APZ42_016706	APZ42_022979	A0A165A3R1	A0A0P5ZVV5	Putative Histone-lysine N-methyltransferase.	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.453
APZ42_016994	APZ42_015255	A0A165AAA8	A0A162PCA2	PIH1 domain-containing protein 1.	Lysine-specific demethylase 6A.	0.484
APZ42_016994	APZ42_034215	A0A165AAA8	A0A164KC51	PIH1 domain-containing protein 1.	Uncharacterized protein.	0.484
APZ42_017723	APZ42_014111	A0A162CJF2	A0A162Q010	E3 ubiquitin-protein ligase TRIP12.	E3 ubiquitin-protein ligase hyd.	0.674
APZ42_022979	APZ42_012709	A0A0P5ZVV5	A0A0P5V584	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.810
APZ42_022979	APZ42_016706	A0A0P5ZVV5	A0A165A3R1	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Putative Histone-lysine N-methyltransferase.	0.453
APZ42_022979	APZ42_030693	A0A0P5ZVV5	A0A164NHN9	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.730
APZ42_022979	APZ42_031507	A0A0P5ZVV5	A0A0N8DAA0	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Breast and ovarian cancer sususceptibility protein.	0.456
APZ42_022979	EOG090X0BB3	A0A0P5ZVV5	A0A0P5EE77	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.730
APZ42_028349	APZ42_012709	A0A0N8ATZ6	A0A0P5V584	REST corepressor 3.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.933
APZ42_030693	APZ42_022979	A0A164NHN9	A0A0P5ZVV5	Autophagy protein 5; Involved in autophagic vesicle formation.	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.730
APZ42_031507	APZ42_022979	A0A0N8DAA0	A0A0P5ZVV5	Breast and ovarian cancer sususceptibility protein.	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.456