(45 nodes) Embryonic hemopoiesis network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_020054	Putative Vascular endothelial growth factor receptor 3. (1011 aa)
	APZ42_020123	Protein kinase domain-containing protein. (468 aa)
	APZ42_020116	Putative Receptor-type tyrosine-protein kinase FLT3. (791 aa)
	APZ42_020161	Putative Vascular endothelial growth factor receptor 1. (994 aa)
	APZ42_020156	Protein kinase domain-containing protein. (1515 aa)
	APZ42_020225	Receptor protein-tyrosine kinase. (1213 aa)
	APZ42_018949	Integrin beta; Belongs to the integrin beta chain family. (786 aa)
	APZ42_029542	Mast/stem cell growth factor receptor Kit. (903 aa)
	APZ42_030789	Ras-related protein Rap-1B. (131 aa)
	APZ42_032465	PDGF-and VEGF-related factor-like protein; Belongs to the PDGF/VEGF growth factor family. (517 aa)
	APZ42_034410	Rho family small gtp binding protein cdc42. (214 aa)
	APZ42_000652	Uncharacterized protein. (215 aa)
	APZ42_003266	Rap guanine nucleotide exchange factor 6. (42 aa)
	APZ42_004669	Ras GTP-binding protein Rho1. (41 aa)
	APZ42_010944	CLIP-associating protein. (805 aa)
	APZ42_011171	Spastin; Belongs to the AAA ATPase family. (674 aa)
	APZ42_029560	Rac GTP-binding protein ARAC9. (191 aa)
	APZ42_011432	Coiled-coil domain-containing protein 134. (233 aa)
	APZ42_013130	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family. (1116 aa)
	APZ42_013134	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit Delta; Belongs to the PI3/PI4-kinase family. (658 aa)
	APZ42_014491	Ras GTP-binding protein RhoL. (187 aa)
	APZ42_014495	Ras GTP-binding protein RhoL. (184 aa)
	APZ42_026236	Ras-related C3 botulinum toxin substrate. (192 aa)
	APZ42_018359	Putative Rho-related GTP-binding protein RhoU. (308 aa)
	APZ42_012615	Rho-related GTP-binding protein RhoF. (223 aa)
	APZ42_032865	Integrin beta; Belongs to the integrin beta chain family. (810 aa)
	APZ42_030255	Integrin beta; Belongs to the integrin beta chain family. (791 aa)
	APZ42_028239	Fascin. (508 aa)
	APZ42_016764	Uncharacterized protein. (560 aa)
	APZ42_013628	Fidgetin protein 1; Belongs to the AAA ATPase family. (618 aa)
	APZ42_032372	Receptor protein-tyrosine kinase. (1457 aa)
	APZ42_013520	Sptzle 1B. (218 aa)
	APZ42_019921	Protein kinase domain-containing protein. (749 aa)
	APZ42_017290	PDGF-and VEGF-related factor-like protein. (159 aa)
	APZ42_019958	Uncharacterized protein. (933 aa)
	APZ42_030530	GCM domain-containing protein. (498 aa)
	APZ42_025710	OCIA domain-containing protein 1. (260 aa)
	APZ42_014594	Rap guanine nucleotide exchange factor 6. (1581 aa)
	APZ42_014363	Integrin beta; Belongs to the integrin beta chain family. (614 aa)
	APZ42_024303	Putative Inactive tyrosine-protein kinase 7. (1141 aa)
	APZ42_022193	Zinc finger protein RP-8. (368 aa)
	APZ42_021685	Tyrosine-protein kinase JAK1. (1217 aa)
	APZ42_025666	Transcription factor glial cells missing. (110 aa)
	APZ42_025854	Uncharacterized protein. (884 aa)
	APZ42_024503	Ras-related C3 botulinum toxin substrate. (195 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_000652	APZ42_004669	A0A164JH90	A0A164GWT3	Uncharacterized protein.	Ras GTP-binding protein Rho1.	0.466
APZ42_000652	APZ42_012615	A0A164JH90	A0A0P5KP21	Uncharacterized protein.	Rho-related GTP-binding protein RhoF.	0.466
APZ42_000652	APZ42_013130	A0A164JH90	A0A162R1L1	Uncharacterized protein.	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family.	0.607
APZ42_000652	APZ42_013134	A0A164JH90	A0A162R1M2	Uncharacterized protein.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit Delta; Belongs to the PI3/PI4-kinase family.	0.607
APZ42_000652	APZ42_013520	A0A164JH90	A0A0P6FSD2	Uncharacterized protein.	Sptzle 1B.	0.509
APZ42_000652	APZ42_014491	A0A164JH90	A0A0P4XH59	Uncharacterized protein.	Ras GTP-binding protein RhoL.	0.506
APZ42_000652	APZ42_014495	A0A164JH90	A0A0P5EG34	Uncharacterized protein.	Ras GTP-binding protein RhoL.	0.506
APZ42_000652	APZ42_017290	A0A164JH90	A0A162CJW3	Uncharacterized protein.	PDGF-and VEGF-related factor-like protein.	0.622
APZ42_000652	APZ42_018359	A0A164JH90	A0A0P5J9Z3	Uncharacterized protein.	Putative Rho-related GTP-binding protein RhoU.	0.506
APZ42_000652	APZ42_024503	A0A164JH90	A0A164TX58	Uncharacterized protein.	Ras-related C3 botulinum toxin substrate.	0.506
APZ42_000652	APZ42_026236	A0A164JH90	A0A0P5IN29	Uncharacterized protein.	Ras-related C3 botulinum toxin substrate.	0.506
APZ42_000652	APZ42_029560	A0A164JH90	A0A164PPI4	Uncharacterized protein.	Rac GTP-binding protein ARAC9.	0.506
APZ42_000652	APZ42_030789	A0A164JH90	A0A164NC55	Uncharacterized protein.	Ras-related protein Rap-1B.	0.509
APZ42_000652	APZ42_032465	A0A164JH90	A0A164LKL1	Uncharacterized protein.	PDGF-and VEGF-related factor-like protein; Belongs to the PDGF/VEGF growth factor family.	0.625
APZ42_000652	APZ42_034410	A0A164JH90	A0A164K509	Uncharacterized protein.	Rho family small gtp binding protein cdc42.	0.506
APZ42_003266	APZ42_004669	A0A164HNS0	A0A164GWT3	Rap guanine nucleotide exchange factor 6.	Ras GTP-binding protein Rho1.	0.559
APZ42_003266	APZ42_012615	A0A164HNS0	A0A0P5KP21	Rap guanine nucleotide exchange factor 6.	Rho-related GTP-binding protein RhoF.	0.559
APZ42_003266	APZ42_013520	A0A164HNS0	A0A0P6FSD2	Rap guanine nucleotide exchange factor 6.	Sptzle 1B.	0.837
APZ42_003266	APZ42_014491	A0A164HNS0	A0A0P4XH59	Rap guanine nucleotide exchange factor 6.	Ras GTP-binding protein RhoL.	0.570
APZ42_003266	APZ42_014495	A0A164HNS0	A0A0P5EG34	Rap guanine nucleotide exchange factor 6.	Ras GTP-binding protein RhoL.	0.570