(22 nodes) Actin nucleation network (Daphnia magna)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	APZ42_033361	Uncharacterized protein. (216 aa)
	APZ42_009912	Wiskott-Aldrich Syndrome protein. (178 aa)
	APZ42_034100	Wiskott-Aldrich Syndrome family protein member. (143 aa)
	APZ42_030183	Uncharacterized protein. (332 aa)
	APZ42_029028	TE: Transposable element Tcb1 Transposase. (348 aa)
	APZ42_022758	WAS family protein. (456 aa)
	EOG090X05RK	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (374 aa)
	APZ42_011508	Actin-related protein 3; Belongs to the actin family. (420 aa)
	APZ42_014982	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (393 aa)
	APZ42_026401	Putative Spire protein. (561 aa)
	APZ42_023248	Spire. (122 aa)
	APZ42_023179	Uncharacterized protein. (298 aa)
	APZ42_022704	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (136 aa)
	APZ42_018049	Putative Wiskott-Aldrich Syndrome protein. (264 aa)
	APZ42_018048	Putative Pleckstrin domain-containing family J member 1. (673 aa)
	APZ42_016357	Actin-related protein 2/3 complex subunit 3. (253 aa)
	EOG090X0FA0	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
	APZ42_012710	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (301 aa)
	APZ42_019000	Putative Wiskott-Aldrich syndrome family protein member 3. (748 aa)
	APZ42_025707	Uncharacterized protein. (1156 aa)
	APZ42_008116	HTH_Tnp_Tc3_2 domain-containing protein. (79 aa)
	APZ42_007733	HTH_Tnp_Tc3_2 domain-containing protein. (80 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_007733	APZ42_009912	A0A164F4E6	A0A162BQ17	HTH_Tnp_Tc3_2 domain-containing protein.	Wiskott-Aldrich Syndrome protein.	0.534
APZ42_007733	APZ42_011508	A0A164F4E6	A0A0P5CCT3	HTH_Tnp_Tc3_2 domain-containing protein.	Actin-related protein 3; Belongs to the actin family.	0.570
APZ42_007733	APZ42_014982	A0A164F4E6	A0A0N8B5N1	HTH_Tnp_Tc3_2 domain-containing protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.597
APZ42_007733	APZ42_018048	A0A164F4E6	A0A164ZIH3	HTH_Tnp_Tc3_2 domain-containing protein.	Putative Pleckstrin domain-containing family J member 1.	0.534
APZ42_007733	APZ42_018049	A0A164F4E6	A0A164ZIE2	HTH_Tnp_Tc3_2 domain-containing protein.	Putative Wiskott-Aldrich Syndrome protein.	0.534
APZ42_007733	APZ42_033361	A0A164F4E6	A0A0P6CBW2	HTH_Tnp_Tc3_2 domain-containing protein.	Uncharacterized protein.	0.472
APZ42_008116	APZ42_009912	A0A164EV39	A0A162BQ17	HTH_Tnp_Tc3_2 domain-containing protein.	Wiskott-Aldrich Syndrome protein.	0.534
APZ42_008116	APZ42_011508	A0A164EV39	A0A0P5CCT3	HTH_Tnp_Tc3_2 domain-containing protein.	Actin-related protein 3; Belongs to the actin family.	0.570
APZ42_008116	APZ42_014982	A0A164EV39	A0A0N8B5N1	HTH_Tnp_Tc3_2 domain-containing protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.597
APZ42_008116	APZ42_018048	A0A164EV39	A0A164ZIH3	HTH_Tnp_Tc3_2 domain-containing protein.	Putative Pleckstrin domain-containing family J member 1.	0.534
APZ42_008116	APZ42_018049	A0A164EV39	A0A164ZIE2	HTH_Tnp_Tc3_2 domain-containing protein.	Putative Wiskott-Aldrich Syndrome protein.	0.534
APZ42_008116	APZ42_033361	A0A164EV39	A0A0P6CBW2	HTH_Tnp_Tc3_2 domain-containing protein.	Uncharacterized protein.	0.458
APZ42_009912	APZ42_007733	A0A162BQ17	A0A164F4E6	Wiskott-Aldrich Syndrome protein.	HTH_Tnp_Tc3_2 domain-containing protein.	0.534
APZ42_009912	APZ42_008116	A0A162BQ17	A0A164EV39	Wiskott-Aldrich Syndrome protein.	HTH_Tnp_Tc3_2 domain-containing protein.	0.534
APZ42_009912	APZ42_011508	A0A162BQ17	A0A0P5CCT3	Wiskott-Aldrich Syndrome protein.	Actin-related protein 3; Belongs to the actin family.	0.963
APZ42_009912	APZ42_012710	A0A162BQ17	A0A0P5TEQ6	Wiskott-Aldrich Syndrome protein.	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.960
APZ42_009912	APZ42_014982	A0A162BQ17	A0A0N8B5N1	Wiskott-Aldrich Syndrome protein.	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.	0.965
APZ42_009912	APZ42_016357	A0A162BQ17	A0A165AD95	Wiskott-Aldrich Syndrome protein.	Actin-related protein 2/3 complex subunit 3.	0.962
APZ42_009912	APZ42_019000	A0A162BQ17	A0A162CG32	Wiskott-Aldrich Syndrome protein.	Putative Wiskott-Aldrich syndrome family protein member 3.	0.701
APZ42_009912	APZ42_022704	A0A162BQ17	A0A164VQF8	Wiskott-Aldrich Syndrome protein.	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.	0.921