(48 nodes) Response to ethanol network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_020472	Apoptosis regulator BAX. (210 aa)
	APZ42_014162	Putative Histone deacetylase silent information regulator protein Sir2. (600 aa)
	APZ42_017495	Dopamine/Ecdysteroid receptor. (387 aa)
	APZ42_033994	Methyltransf_21 domain-containing protein. (316 aa)
	APZ42_020981	Disks large 1 tumor suppressor protein; Belongs to the MAGUK family. (912 aa)
	APZ42_022814	Methyltransf_21 domain-containing protein. (331 aa)
	APZ42_012137	Glutamate receptor ionotropic, NMDA. (989 aa)
	APZ42_020167	Methyltransf_21 domain-containing protein. (330 aa)
	APZ42_022105	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (770 aa)
	APZ42_015422	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (486 aa)
	APZ42_011760	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide. (952 aa)
	APZ42_010942	Uncharacterized protein. (290 aa)
	APZ42_033483	Phosphoserine phosphatase. (224 aa)
	APZ42_013562	Arfaptin-2. (361 aa)
	APZ42_023061	Serine/threonine protein kinase TAO1 alpha. (942 aa)
	EOG090X0AKT	Leucine zipper containing transcription factor. (268 aa)
	APZ42_022906	Inositol 1,4,5-trisphosphate receptor type. (2851 aa)
	APZ42_018401	Acetyl-coenzyme A synthetase. (652 aa)
	APZ42_028089	Glutamate--cysteine ligase regulatory subunit. (236 aa)
	APZ42_022799	Methyltransf_21 domain-containing protein. (374 aa)
	APZ42_014948	Putative Pumilio. (1214 aa)
	APZ42_015225	Putative E3 ubiquitin-protein ligase RNF181. (823 aa)
	APZ42_015385	Synapsin. (568 aa)
	APZ42_013661	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (468 aa)
	APZ42_012646	Methyltransf_21 domain-containing protein. (262 aa)
	APZ42_011684	cAMP-dependent protein kinase type II regulatory subunit. (305 aa)
	APZ42_004793	Uncharacterized protein. (299 aa)
	APZ42_002400	Putative Acetyl-Coenzyme A synthetase. (210 aa)
	APZ42_001748	Putative cAMP-dependent protein kinase type I regulatory subunit. (99 aa)
	APZ42_032730	PKS_ER domain-containing protein. (372 aa)
	APZ42_031488	Extra bases protein. (418 aa)
	APZ42_030805	Methyltransf_21 domain-containing protein. (257 aa)
	APZ42_030650	Fascilin 2-like protein. (771 aa)
	APZ42_028700	Mitogen-activated protein kinase kinase kinase kinase. (382 aa)
	APZ42_026816	Peripheral plasma membrane protein CASK. (318 aa)
	APZ42_023808	Gonadotropin-releasing hormone II receptor. (424 aa)
	APZ42_022288	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (227 aa)
	APZ42_022813	Methyltransf_21 domain-containing protein. (334 aa)
	APZ42_022874	DBH monooxygenase 1-like protein. (636 aa)
	APZ42_022112	Phorbol-ester/DAG-type domain-containing protein. (159 aa)
	APZ42_022156	G-protein coupled receptor 26; Belongs to the G-protein coupled receptor 1 family. (412 aa)
	APZ42_021539	cAMP-dependent protein kinase type I regulatory subunit. (331 aa)
	APZ42_021036	Uncharacterized protein. (103 aa)
	APZ42_020077	Methyltransf_21 domain-containing protein. (356 aa)
	APZ42_018044	Uncharacterized protein. (170 aa)
	APZ42_016906	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (205 aa)
	APZ42_016294	Acetyl-coenzyme A synthetase. (630 aa)
	APZ42_016548	Protein kinase domain-containing protein. (927 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_001748	APZ42_002400	A0A164IRW4	A0A164IAC2	Putative cAMP-dependent protein kinase type I regulatory subunit.	Putative Acetyl-Coenzyme A synthetase.	0.529
APZ42_001748	APZ42_016294	A0A164IRW4	A0A165ACK3	Putative cAMP-dependent protein kinase type I regulatory subunit.	Acetyl-coenzyme A synthetase.	0.529
APZ42_001748	APZ42_018401	A0A164IRW4	A0A0P6GZT6	Putative cAMP-dependent protein kinase type I regulatory subunit.	Acetyl-coenzyme A synthetase.	0.529
APZ42_001748	APZ42_022906	A0A164IRW4	A0A0P5ZUN0	Putative cAMP-dependent protein kinase type I regulatory subunit.	Inositol 1,4,5-trisphosphate receptor type.	0.522
APZ42_002400	APZ42_001748	A0A164IAC2	A0A164IRW4	Putative Acetyl-Coenzyme A synthetase.	Putative cAMP-dependent protein kinase type I regulatory subunit.	0.529
APZ42_002400	APZ42_011684	A0A164IAC2	A0A162SX03	Putative Acetyl-Coenzyme A synthetase.	cAMP-dependent protein kinase type II regulatory subunit.	0.529
APZ42_002400	APZ42_014162	A0A164IAC2	A0A162Q0V9	Putative Acetyl-Coenzyme A synthetase.	Putative Histone deacetylase silent information regulator protein Sir2.	0.510
APZ42_002400	APZ42_021539	A0A164IAC2	A0A164WKP3	Putative Acetyl-Coenzyme A synthetase.	cAMP-dependent protein kinase type I regulatory subunit.	0.529
APZ42_002400	APZ42_032730	A0A164IAC2	A0A164LUV6	Putative Acetyl-Coenzyme A synthetase.	PKS_ER domain-containing protein.	0.539
APZ42_004793	APZ42_011760	A0A164GUB4	A0A0P5KQF9	Uncharacterized protein.	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide.	0.430
APZ42_004793	APZ42_016548	A0A164GUB4	A0A165AHT4	Uncharacterized protein.	Protein kinase domain-containing protein.	0.900
APZ42_004793	APZ42_020472	A0A164GUB4	A0A0P4XHJ8	Uncharacterized protein.	Apoptosis regulator BAX.	0.508
APZ42_004793	APZ42_020981	A0A164GUB4	A0A0P4ZGY7	Uncharacterized protein.	Disks large 1 tumor suppressor protein; Belongs to the MAGUK family.	0.689
APZ42_004793	APZ42_022105	A0A164GUB4	A0A0P5F335	Uncharacterized protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.595
APZ42_004793	APZ42_022112	A0A164GUB4	A0A164W2E4	Uncharacterized protein.	Phorbol-ester/DAG-type domain-containing protein.	0.595
APZ42_004793	APZ42_026816	A0A164GUB4	A0A164RYF7	Uncharacterized protein.	Peripheral plasma membrane protein CASK.	0.665
APZ42_004793	APZ42_028700	A0A164GUB4	A0A164QBP4	Uncharacterized protein.	Mitogen-activated protein kinase kinase kinase kinase.	0.709
APZ42_004793	APZ42_032730	A0A164GUB4	A0A164LUV6	Uncharacterized protein.	PKS_ER domain-containing protein.	0.481
APZ42_011684	APZ42_002400	A0A162SX03	A0A164IAC2	cAMP-dependent protein kinase type II regulatory subunit.	Putative Acetyl-Coenzyme A synthetase.	0.529
APZ42_011684	APZ42_016294	A0A162SX03	A0A165ACK3	cAMP-dependent protein kinase type II regulatory subunit.	Acetyl-coenzyme A synthetase.	0.529