(104 nodes) Positive regulation of cell differentiation network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_016204	Uncharacterized protein. (913 aa)
	APZ42_016508	Uncharacterized protein. (426 aa)
	APZ42_016320	Putative Biogenesis of lysosome-related organelles complex 1 subunit 5. (122 aa)
	APZ42_016881	RWD domain-containing protein. (286 aa)
	APZ42_016821	HMG box domain-containing protein. (544 aa)
	APZ42_017454	Cytokine-inducible SH2-containing protein. (483 aa)
	APZ42_017263	Programmed cell death protein 4. (464 aa)
	APZ42_018475	X-ray repair cross-complementing protein 5. (122 aa)
	APZ42_019106	Putative Basement membrane-specific heparan sulfate proteoglycan core protein. (575 aa)
	APZ42_019324	Putative NF-kappa-B inhibitor zeta. (908 aa)
	APZ42_019405	Histone-lysine N-methyltransferase EHMT1. (1097 aa)
	APZ42_020194	Putative Osteoclast-stimulating factor 1. (187 aa)
	APZ42_019772	Putative T-lymphoma invasion and metastasis-inducing protein 2. (1988 aa)
	APZ42_020324	Putative Transcription factor HES-2. (590 aa)
	APZ42_020359	Homeobox domain-containing protein. (275 aa)
	APZ42_020849	Plexin-A4. (140 aa)
	APZ42_020835	Plexin-A4. (1213 aa)
	APZ42_020539	Protocadherin wing polarity protein stan; Belongs to the G-protein coupled receptor 2 family. (1930 aa)
	APZ42_020519	Putative Protocadherin wing polarity protein stan. (102 aa)
	APZ42_021220	Spichthyin. (331 aa)
	APZ42_021855	Photoreceptor-specific nuclear receptor. (734 aa)
	APZ42_022148	Putative Serine/threonine-protein kinase minibrain. (694 aa)
	APZ42_022001	Uncharacterized protein. (1211 aa)
	APZ42_022865	Putative Bruno-3. (377 aa)
	APZ42_022275	Dynein heavy chain, cytoplasmic. (4656 aa)
	APZ42_022990	Chromatin accessibility complex 14kD protein. (209 aa)
	APZ42_023127	Mitogen-activated protein kinase. (401 aa)
	APZ42_023261	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family. (192 aa)
	APZ42_023326	Hsp90 co-chaperone Cdc37. (340 aa)
	APZ42_023394	Plexin-A4. (462 aa)
	APZ42_023508	Vang 1-like protein. (474 aa)
	APZ42_024199	DUF1279 domain-containing protein. (231 aa)
	APZ42_024747	Fragile X mental retardation Syndrome-related protein. (637 aa)
	APZ42_024874	HMG box domain-containing protein. (431 aa)
	APZ42_025310	Uncharacterized protein. (661 aa)
	APZ42_026107	Raf serine/threonine-protein kinase phl. (913 aa)
	APZ42_026502	GTP-binding protein Rheb. (185 aa)
	APZ42_026542	RIO kinase 2. (515 aa)
	APZ42_028403	Plexin-A4. (1539 aa)
	APZ42_028571	Activating molecule in BECN1-regulated autophagy 1-like protein. (1394 aa)
	APZ42_029475	Putative Insulinoma-associated protein. (796 aa)
	APZ42_029781	F-box domain-containing protein. (442 aa)
	APZ42_031535	PITH domain-containing protein 1. (207 aa)
	APZ42_031690	Proliferation-associated protein 2G4. (387 aa)
	APZ42_032079	F-box domain-containing protein. (447 aa)
	APZ42_034306	Uncharacterized protein. (668 aa)
	APZ42_034413	NTR domain-containing protein. (170 aa)
	APZ42_034408	Bone morphogenetic protein 8A. (419 aa)
	APZ42_002599	Plexin-A4. (425 aa)
	APZ42_010932	Transcription factor runt-like protein. (501 aa)
	APZ42_010863	Zinc finger C4H2 domain-containing protein. (264 aa)
	APZ42_011171	Spastin; Belongs to the AAA ATPase family. (674 aa)
	APZ42_011470	Putative Transcription factor prospero. (962 aa)
	APZ42_012209	Putative Myogenic factor 6. (316 aa)
	EOG090X0BA8	Mps one binder kinase activator 4 mob as tumor suppressor protein 4 dmob4. (227 aa)
	APZ42_020419	TSC22 domain family, member. (819 aa)
	APZ42_029764	F-box/WD repeat-containing protein 1A. (510 aa)
	APZ42_013638	Kinase domain-containing protein, cytoplasmic. (323 aa)
	APZ42_015396	Reversed polarity homeodomain-like protein. (354 aa)
	APZ42_020441	Caprin-1. (617 aa)
	APZ42_030563	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (803 aa)
	APZ42_012127	Integrator complex subunit 5. (1052 aa)
	APZ42_017329	Nuclear distribution protein nudE 1-B. (307 aa)
	APZ42_023819	G2/mitotic-specific cyclin-A; Belongs to the cyclin family. (451 aa)
	APZ42_015145	Striatin-3. (780 aa)
	APZ42_029568	Chromaffin granule amine transporter. (499 aa)
	APZ42_032636	Seipin. (404 aa)
	APZ42_014019	Transcriptional coactivator YAP1. (461 aa)
	APZ42_018598	LIM domain-containing protein. (342 aa)
	APZ42_024863	Uncharacterized protein. (468 aa)
	APZ42_011718	Cellular tumor antigen p53. (413 aa)
	APZ42_011771	WD_REPEATS_REGION domain-containing protein. (493 aa)
	APZ42_022070	Zinc finger and SCAN domain-containing protein. (776 aa)
	APZ42_027371	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (624 aa)
	APZ42_031954	Integrator complex subunit 8. (1010 aa)
	APZ42_024809	Non-specific serine/threonine protein kinase. (829 aa)
	APZ42_012329	Uncharacterized protein. (729 aa)
	APZ42_024808	Disheveled-associated activator of morphogenesis 2. (1204 aa)
	APZ42_032822	Atlastin-3. (536 aa)
	APZ42_020417	Kinase c and casein kinase substrate in neurons protein. (534 aa)
	APZ42_026322	Putative Segment polarity protein dishevelled. (699 aa)
	APZ42_016764	Uncharacterized protein. (560 aa)
	APZ42_013628	Fidgetin protein 1; Belongs to the AAA ATPase family. (618 aa)
	APZ42_028289	Sensitized chromosome inheritance modifier. (747 aa)
	APZ42_033658	Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (529 aa)
	APZ42_013618	Brefeldin A-inhibited guanine nucleotide-exchange protein 1. (1708 aa)
	APZ42_020506	Protocadherin wing polarity protein stan. (1301 aa)
	APZ42_003083	BMP and activin membrane-bound inhibitor. (204 aa)
	APZ42_032689	Integrator 1. (2131 aa)
	APZ42_026385	ALG-2 interacting protein X. (1756 aa)
	APZ42_015739	Integrator 2. (1242 aa)
	APZ42_015601	Plexin-A4. (271 aa)
	APZ42_015540	Putative Still life type 1. (718 aa)
	APZ42_015074	Microtubule-actin cross-linking factor 1. (5007 aa)
	APZ42_014785	Myc, dMyc-like protein. (178 aa)
	APZ42_013806	Putative GA-binding protein alpha chain. (380 aa)
	APZ42_013388	Putative Basement membrane-specific heparan sulfate proteoglycan core protein. (1513 aa)
	APZ42_013130	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family. (1116 aa)
	APZ42_013134	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit Delta; Belongs to the PI3/PI4-kinase family. (658 aa)
	EOG090X0AH4	Nuclear migration protein nudC. (320 aa)
	APZ42_012055	Putative Transcriptional factor Ocelliless/Orthodenticle protein. (494 aa)
	APZ42_032885	F-box domain-containing protein. (183 aa)
	APZ42_024116	Jouberin. (817 aa)
	APZ42_014767	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma. (433 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_002599	APZ42_015601	A0A164I614	A0A162NU14	Plexin-A4.	Plexin-A4.	0.920
APZ42_002599	APZ42_020835	A0A164I614	A0A164XFJ3	Plexin-A4.	Plexin-A4.	0.932
APZ42_002599	APZ42_024809	A0A164I614	A0A0P5WNT8	Plexin-A4.	Non-specific serine/threonine protein kinase.	0.485
APZ42_002599	APZ42_026385	A0A164I614	A0A162DAZ1	Plexin-A4.	ALG-2 interacting protein X.	0.513
APZ42_002599	APZ42_026502	A0A164I614	A0A164S9X2	Plexin-A4.	GTP-binding protein Rheb.	0.573
APZ42_002599	APZ42_028403	A0A164I614	A0A164QIQ8	Plexin-A4.	Plexin-A4.	0.932
APZ42_003083	APZ42_026322	A0A162CXH5	A0A0P5YKA8	BMP and activin membrane-bound inhibitor.	Putative Segment polarity protein dishevelled.	0.785
APZ42_003083	APZ42_031954	A0A162CXH5	A0A0P5WNF3	BMP and activin membrane-bound inhibitor.	Integrator complex subunit 8.	0.656
APZ42_003083	APZ42_034408	A0A162CXH5	A0A164K5C9	BMP and activin membrane-bound inhibitor.	Bone morphogenetic protein 8A.	0.561
APZ42_003083	APZ42_034413	A0A162CXH5	A0A164K605	BMP and activin membrane-bound inhibitor.	NTR domain-containing protein.	0.603
APZ42_010932	APZ42_011718	A0A162TAT4	A0A0P5UBN4	Transcription factor runt-like protein.	Cellular tumor antigen p53.	0.619
APZ42_010932	APZ42_013806	A0A162TAT4	A0A162QG25	Transcription factor runt-like protein.	Putative GA-binding protein alpha chain.	0.907
APZ42_010932	APZ42_014019	A0A162TAT4	A0A0P5H4F2	Transcription factor runt-like protein.	Transcriptional coactivator YAP1.	0.792
APZ42_010932	APZ42_016764	A0A162TAT4	A0A0P5YY01	Transcription factor runt-like protein.	Uncharacterized protein.	0.698
APZ42_010932	APZ42_016821	A0A162TAT4	A0A165A7D1	Transcription factor runt-like protein.	HMG box domain-containing protein.	0.602
APZ42_010932	APZ42_017454	A0A162TAT4	A0A164ZVY8	Transcription factor runt-like protein.	Cytokine-inducible SH2-containing protein.	0.483
APZ42_010932	APZ42_022148	A0A162TAT4	A0A164W2J5	Transcription factor runt-like protein.	Putative Serine/threonine-protein kinase minibrain.	0.529
APZ42_010932	APZ42_024874	A0A162TAT4	A0A164TMW6	Transcription factor runt-like protein.	HMG box domain-containing protein.	0.602
APZ42_010932	APZ42_031954	A0A162TAT4	A0A0P5WNF3	Transcription factor runt-like protein.	Integrator complex subunit 8.	0.623
APZ42_010932	APZ42_034408	A0A162TAT4	A0A164K5C9	Transcription factor runt-like protein.	Bone morphogenetic protein 8A.	0.525