(75 nodes) Negative regulation of proteolysis network (Daphnia magna)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_009866	BPTI/Kunitz inhibitor domain-containing protein. (112 aa)
	APZ42_007860	Antistasin-like domain-containing protein. (76 aa)
	APZ42_004538	Uncharacterized protein. (306 aa)
	APZ42_002653	Uncharacterized protein. (161 aa)
	APZ42_001900	Uncharacterized protein. (266 aa)
	APZ42_001737	Thyroglobulin type-1 domain-containing protein. (266 aa)
	APZ42_034554	Protein Z-dependent protease inhibitor; Belongs to the serpin family. (724 aa)
	APZ42_034436	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2457 aa)
	APZ42_033737	Reversion-inducing cysteine-rich protein with Kazal motifs. (845 aa)
	APZ42_033575	Uncharacterized protein. (428 aa)
	APZ42_033062	Uncharacterized protein. (417 aa)
	APZ42_033026	Uncharacterized protein. (418 aa)
	APZ42_032943	Serpin 28B; Belongs to the serpin family. (408 aa)
	APZ42_032431	Uncharacterized protein. (1612 aa)
	APZ42_031875	Spondin-1. (53 aa)
	APZ42_031870	Spondin-1. (671 aa)
	APZ42_030798	Serpin B13; Belongs to the serpin family. (785 aa)
	APZ42_030649	Sortilin-related receptor. (2218 aa)
	APZ42_026978	CD109 antigen. (703 aa)
	APZ42_026971	Putative CD109 antigen. (2614 aa)
	APZ42_026988	Uncharacterized protein. (295 aa)
	APZ42_026670	Cystatin-like protein. (502 aa)
	APZ42_025755	Putative Notch. (199 aa)
	APZ42_025075	Uncharacterized protein. (1175 aa)
	APZ42_022927	Baculoviral IAP repeat-containing protein 6. (4631 aa)
	APZ42_022756	Uncharacterized protein. (359 aa)
	APZ42_022765	Uncharacterized protein. (361 aa)
	APZ42_021040	Uncharacterized protein. (1073 aa)
	APZ42_019849	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (365 aa)
	APZ42_020051	Death-associated inhibitor of apoptosis 1. (405 aa)
	APZ42_020094	BPTI/Kunitz inhibitor domain-containing protein. (80 aa)
	APZ42_018391	Papilin. (2817 aa)
	APZ42_016994	PIH1 domain-containing protein 1. (208 aa)
	APZ42_020067	Putative Lactosylceramide. (203 aa)
	APZ42_013754	COP9 signalosome complex subunit 5. (341 aa)
	APZ42_030627	Ragulator complex protein LAMTOR5. (90 aa)
	APZ42_031306	Lactosylceramide. (357 aa)
	APZ42_022635	Uncharacterized protein. (322 aa)
	APZ42_020070	Lactosylceramide. (325 aa)
	APZ42_027202	Transmembrane protein 98. (242 aa)
	APZ42_016229	Putative Growth arrest-specific protein 1. (390 aa)
	APZ42_030562	Proteasome activator complex subunit 3. (242 aa)
	APZ42_021706	Serine/threonine/tyrosine-interacting protein. (205 aa)
	APZ42_017804	COP9 signalosome complex subunit 4. (407 aa)
	APZ42_014874	Proteasome inhibitor PI31 subunit. (265 aa)
	APZ42_025291	Lactosylceramide. (323 aa)
	APZ42_015622	Serine protease inhibitor serpin; Belongs to the serpin family. (461 aa)
	APZ42_031794	Delta(24)-sterol reductase. (537 aa)
	APZ42_023089	Delta(24)-sterol reductase. (519 aa)
	APZ42_013335	Putative Cathepsin o; Belongs to the cystatin family. (252 aa)
	APZ42_023581	FAS-associated factor 1. (665 aa)
	APZ42_016494	UBX domain-containing protein 1. (317 aa)
	APZ42_032932	Protein Z-dependent protease inhibitor; Belongs to the serpin family. (446 aa)
	APZ42_018917	Serine/threonine-protein kinase hippo. (576 aa)
	APZ42_004537	VWFA domain-containing protein. (177 aa)
	APZ42_034500	Serpin B13; Belongs to the serpin family. (461 aa)
	APZ42_018461	C3 and PZP alpha-2-macroglobulin domain-containing protein 8. (710 aa)
	APZ42_017418	Uncharacterized protein. (323 aa)
	APZ42_011380	Ubiquitin carboxyl-terminal hydrolase 47; Belongs to the peptidase C19 family. (1402 aa)
	APZ42_001899	Uncharacterized protein. (177 aa)
	APZ42_028438	CD109 antigen-like protein. (188 aa)
	APZ42_025536	TEP1 protein. (1772 aa)
	APZ42_026442	Protein crumbs. (2334 aa)
	APZ42_015544	C3 and PZP alpha-2-macroglobulin domain-containing protein 8. (897 aa)
	APZ42_015533	CD109 antigen. (1550 aa)
	APZ42_015395	Tissue inhibitor of metalloproteases. (244 aa)
	APZ42_014816	Tumor necrosis factor alpha-induced 8 protein 2-like protein. (187 aa)
	APZ42_014427	Uncharacterized protein. (648 aa)
	APZ42_013599	Ubiquitin carboxyl-terminal hydrolase. (968 aa)
	APZ42_013327	Uncharacterized protein. (1139 aa)
	APZ42_012707	Contactin associated protein-like 5-1. (2090 aa)
	APZ42_012711	Protein FAM192A. (233 aa)
	APZ42_012138	Baculoviral IAP repeat-containing protein 8. (505 aa)
	APZ42_012213	Vasopressin neuropeptide preprohormone-like protein. (150 aa)
	APZ42_011333	TEP1 protein. (2459 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_001737	APZ42_019849	A0A164IS78	A0A164XSG1	Thyroglobulin type-1 domain-containing protein.	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily.	0.447
APZ42_001899	APZ42_019849	A0A162CZN7	A0A164XSG1	Uncharacterized protein.	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily.	0.447
APZ42_001899	APZ42_025075	A0A162CZN7	A0A164THD7	Uncharacterized protein.	Uncharacterized protein.	0.452
APZ42_001900	APZ42_019849	A0A164INE1	A0A164XSG1	Uncharacterized protein.	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily.	0.447
APZ42_004537	APZ42_004538	A0A162C0B4	A0A164GZW7	VWFA domain-containing protein.	Uncharacterized protein.	0.586
APZ42_004537	APZ42_033062	A0A162C0B4	A0A164LFP8	VWFA domain-containing protein.	Uncharacterized protein.	0.573
APZ42_004538	APZ42_004537	A0A164GZW7	A0A162C0B4	Uncharacterized protein.	VWFA domain-containing protein.	0.586
APZ42_007860	APZ42_019849	A0A164F1H5	A0A164XSG1	Antistasin-like domain-containing protein.	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily.	0.447
APZ42_012138	APZ42_018917	A0A162S4Z3	A0A0P6EU47	Baculoviral IAP repeat-containing protein 8.	Serine/threonine-protein kinase hippo.	0.404
APZ42_012138	APZ42_022927	A0A162S4Z3	A0A164VB86	Baculoviral IAP repeat-containing protein 8.	Baculoviral IAP repeat-containing protein 6.	0.718
APZ42_012138	APZ42_030649	A0A162S4Z3	A0A164NQH8	Baculoviral IAP repeat-containing protein 8.	Sortilin-related receptor.	0.545
APZ42_012711	APZ42_030562	A0A162RJN6	A0A0P5H4J1	Protein FAM192A.	Proteasome activator complex subunit 3.	0.887
APZ42_013335	APZ42_022927	A0A0P5Z870	A0A164VB86	Putative Cathepsin o; Belongs to the cystatin family.	Baculoviral IAP repeat-containing protein 6.	0.487
APZ42_013754	APZ42_017804	A0A0N8D7N5	A0A0P5SRQ1	COP9 signalosome complex subunit 5.	COP9 signalosome complex subunit 4.	0.999
APZ42_013754	APZ42_022927	A0A0N8D7N5	A0A164VB86	COP9 signalosome complex subunit 5.	Baculoviral IAP repeat-containing protein 6.	0.647
APZ42_014874	APZ42_022927	A0A0P5X5X2	A0A164VB86	Proteasome inhibitor PI31 subunit.	Baculoviral IAP repeat-containing protein 6.	0.688
APZ42_014874	APZ42_030562	A0A0P5X5X2	A0A0P5H4J1	Proteasome inhibitor PI31 subunit.	Proteasome activator complex subunit 3.	0.719
APZ42_015395	APZ42_033737	A0A162PG48	A0A164KUE8	Tissue inhibitor of metalloproteases.	Reversion-inducing cysteine-rich protein with Kazal motifs.	0.534
APZ42_015544	APZ42_018461	A0A162NUN4	A0A162CHE4	C3 and PZP alpha-2-macroglobulin domain-containing protein 8.	C3 and PZP alpha-2-macroglobulin domain-containing protein 8.	0.943
APZ42_015622	APZ42_030649	A0A0P5YGC7	A0A164NQH8	Serine protease inhibitor serpin; Belongs to the serpin family.	Sortilin-related receptor.	0.489