(84 nodes) Membrane lipid biosynthetic process network (Daphnia magna)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	APZ42_034089	Beta-1,4-galactosyltransferase 6. (368 aa)
	APZ42_011815	GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. (476 aa)
	APZ42_021848	Sphingomyelin phosphodiesterase 3. (467 aa)
	APZ42_028595	Mannosyltransferase. (613 aa)
	APZ42_027256	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (590 aa)
	APZ42_030445	Longevity assurance factor 1 lag1. (295 aa)
	APZ42_012622	Ceramide glucosyltransferase. (399 aa)
	APZ42_012883	GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. (416 aa)
	APZ42_022825	Lactosylceramide. (332 aa)
	APZ42_027246	Saccharopine dehydrogenase oxidoreductase-like protein. (425 aa)
	EOG090X0B9X	Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. (240 aa)
	APZ42_016713	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (384 aa)
	APZ42_025828	Sphingomyelin synthase-related protein 1. (485 aa)
	APZ42_030439	Longevity assurance factor 1 lag1. (371 aa)
	APZ42_016108	Neutral sphingomyelinase. (390 aa)
	EOG090X0702	Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family. (320 aa)
	APZ42_030523	3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (336 aa)
	APZ42_033138	Post-GPI attachment to proteins factor 2. (283 aa)
	APZ42_021979	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (364 aa)
	APZ42_022878	Elongation of very long chain fatty acids protein. (283 aa)
	APZ42_029601	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (587 aa)
	APZ42_013209	Serine palmitoyltransferase subunit I. (468 aa)
	APZ42_022801	Lactosylceramide. (369 aa)
	APZ42_017206	Phosphatidylinositol glycan anchor biosynthesis class U protein. (426 aa)
	APZ42_011616	Mannosyltransferase. (480 aa)
	APZ42_027295	Saccharopine dehydrogenase oxidoreductase-like protein. (422 aa)
	APZ42_020555	Phosphatidylcholine:ceramide cholinephosphotransferase. (443 aa)
	APZ42_031375	Lactosylceramide. (369 aa)
	APZ42_022106	Putative Glycosylphosphatidylinositol anchor attachment 1 protein. (621 aa)
	APZ42_011360	Elongation of very long chain fatty acids protein. (276 aa)
	APZ42_014895	Putative Galactose-3-O-sulfotransferase 2. (413 aa)
	APZ42_024026	Lactosylceramide 4-alpha-galactosyltransferase. (405 aa)
	APZ42_017405	Putative Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q. (488 aa)
	APZ42_023462	Beta-1,4-galactosyltransferase. (341 aa)
	APZ42_018961	Galactose-3-o-sulfotransferase. (391 aa)
	APZ42_029775	Beta-1,4-mannosyltransferase egh. (519 aa)
	APZ42_011725	Sphingosine kinase 1. (485 aa)
	APZ42_026528	Longevity assurance protein. (393 aa)
	APZ42_012249	Cell division control protein/dna repair exonuclease. (343 aa)
	APZ42_014835	GPI ethanolamine phosphate transferase 1. (888 aa)
	APZ42_033027	Lactosylceramide 4-alpha-galactosyltransferase. (396 aa)
	APZ42_019998	Putative Galactose-3-O-sulfotransferase 2. (1399 aa)
	APZ42_020186	Alpha-1,4-N-acetylglucosaminyltransferase. (403 aa)
	APZ42_004124	Putative Lactosylceramide 4-alpha-galactosyltransferase. (94 aa)
	APZ42_002320	Elongation of very long chain fatty acids protein. (104 aa)
	APZ42_011362	Elongation of very long chain fatty acids protein. (496 aa)
	APZ42_031916	Des-1 protein; Belongs to the fatty acid desaturase type 1 family. DEGS subfamily. (324 aa)
	APZ42_025860	Torsin-like protein. (351 aa)
	APZ42_015797	Sphingomyelin phosphodiesterase 4. (798 aa)
	APZ42_014680	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (579 aa)
	APZ42_014681	Metallophos domain-containing protein. (333 aa)
	APZ42_011431	Post-GPI attachment to proteins factor 2. (257 aa)
	APZ42_011427	Acylglycerol kinase. (368 aa)
	APZ42_011806	GPI ethanolamine phosphate transferase 3. (865 aa)
	APZ42_002319	Elongation of very long chain fatty acids protein. (104 aa)
	APZ42_000379	Alpha4GT1. (370 aa)
	APZ42_034582	Beta4GalNAcTB. (384 aa)
	APZ42_034142	N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase. (304 aa)
	APZ42_033704	GPI ethanolamine phosphate transferase 2. (854 aa)
	APZ42_033555	N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein. (360 aa)
	APZ42_033290	Alpha4GT1. (397 aa)
	APZ42_033084	Mitochondrial pyruvate carrier 1. (570 aa)
	APZ42_031651	Putative Phosphatidylinositol-glycan biosynthesis class F protein. (220 aa)
	APZ42_031075	Sphingomyelin phosphodiesterase. (315 aa)
	APZ42_031076	Sphingomyelin phosphodiesterase. (344 aa)
	APZ42_030678	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (229 aa)
	APZ42_030123	Uncharacterized protein. (741 aa)
	APZ42_029330	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (187 aa)
	APZ42_028299	Phosphatidylinositol-glycan biosynthesis class W protein. (360 aa)
	APZ42_027269	Saposin B-type domain-containing protein. (249 aa)
	APZ42_025861	Metallophosphoesterase. (351 aa)
	APZ42_024402	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (591 aa)
	APZ42_022764	Putative Beta-1,4-N-acetylgalactosaminyltransferase BRE-4. (333 aa)
	APZ42_022820	Lactosylceramide 4-alpha-galactosyltransferase. (363 aa)
	APZ42_019953	GPI transamidase component PIG-T. (548 aa)
	APZ42_020022	Galactosylceramide sulfotransferase. (403 aa)
	APZ42_020068	Gb3_synth domain-containing protein. (305 aa)
	APZ42_020124	Uncharacterized protein. (401 aa)
	APZ42_018610	Serine palmitoyltransferase 2. (450 aa)
	APZ42_018900	Elongation of very long chain fatty acids protein. (113 aa)
	APZ42_018283	Elongation of very long chain fatty acids protein. (313 aa)
	APZ42_018280	Putative Galactose-3-O-sulfotransferase 2. (369 aa)
	APZ42_017138	Beta-1,4-galactosyltransferase 6. (371 aa)
	APZ42_016255	ATP-dependent DNA helicase; Belongs to the helicase family. (561 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_000379	APZ42_017138	A0A164JQ10	A0A164ZNK7	Alpha4GT1.	Beta-1,4-galactosyltransferase 6.	0.519
APZ42_000379	APZ42_022764	A0A164JQ10	A0A164VSX9	Alpha4GT1.	Putative Beta-1,4-N-acetylgalactosaminyltransferase BRE-4.	0.519
APZ42_000379	APZ42_023462	A0A164JQ10	A0A0P5YWP8	Alpha4GT1.	Beta-1,4-galactosyltransferase.	0.595
APZ42_000379	APZ42_034089	A0A164JQ10	A0A0N8AFV4	Alpha4GT1.	Beta-1,4-galactosyltransferase 6.	0.593
APZ42_000379	APZ42_034582	A0A164JQ10	A0A164K0H4	Alpha4GT1.	Beta4GalNAcTB.	0.519
APZ42_002319	APZ42_011360	A0A164ICI3	A0A0P5YBM0	Elongation of very long chain fatty acids protein.	Elongation of very long chain fatty acids protein.	0.561
APZ42_002319	APZ42_011362	A0A164ICI3	A0A162CZ02	Elongation of very long chain fatty acids protein.	Elongation of very long chain fatty acids protein.	0.650
APZ42_002319	APZ42_018283	A0A164ICI3	A0A164Z7I5	Elongation of very long chain fatty acids protein.	Elongation of very long chain fatty acids protein.	0.648
APZ42_002319	APZ42_029330	A0A164ICI3	A0A164PQZ2	Elongation of very long chain fatty acids protein.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.691
APZ42_002319	APZ42_030678	A0A164ICI3	A0A164NH61	Elongation of very long chain fatty acids protein.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.709
APZ42_002320	APZ42_011360	A0A162CYY7	A0A0P5YBM0	Elongation of very long chain fatty acids protein.	Elongation of very long chain fatty acids protein.	0.558
APZ42_002320	APZ42_011362	A0A162CYY7	A0A162CZ02	Elongation of very long chain fatty acids protein.	Elongation of very long chain fatty acids protein.	0.649
APZ42_002320	APZ42_018283	A0A162CYY7	A0A164Z7I5	Elongation of very long chain fatty acids protein.	Elongation of very long chain fatty acids protein.	0.648
APZ42_002320	APZ42_029330	A0A162CYY7	A0A164PQZ2	Elongation of very long chain fatty acids protein.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.691
APZ42_002320	APZ42_030678	A0A162CYY7	A0A164NH61	Elongation of very long chain fatty acids protein.	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]	0.709
APZ42_004124	APZ42_017138	A0A162CVQ5	A0A164ZNK7	Putative Lactosylceramide 4-alpha-galactosyltransferase.	Beta-1,4-galactosyltransferase 6.	0.519
APZ42_004124	APZ42_022764	A0A162CVQ5	A0A164VSX9	Putative Lactosylceramide 4-alpha-galactosyltransferase.	Putative Beta-1,4-N-acetylgalactosaminyltransferase BRE-4.	0.519
APZ42_004124	APZ42_023462	A0A162CVQ5	A0A0P5YWP8	Putative Lactosylceramide 4-alpha-galactosyltransferase.	Beta-1,4-galactosyltransferase.	0.572
APZ42_004124	APZ42_034089	A0A162CVQ5	A0A0N8AFV4	Putative Lactosylceramide 4-alpha-galactosyltransferase.	Beta-1,4-galactosyltransferase 6.	0.518
APZ42_004124	APZ42_034582	A0A162CVQ5	A0A164K0H4	Putative Lactosylceramide 4-alpha-galactosyltransferase.	Beta4GalNAcTB.	0.519