(101 nodes) Digestive tract development network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_011069	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (553 aa)
	APZ42_034553	Lines protein. (673 aa)
	APZ42_023386	Putative Daughterless protein. (68 aa)
	APZ42_024116	Jouberin. (817 aa)
	APZ42_023127	Mitogen-activated protein kinase. (401 aa)
	APZ42_022813	Methyltransf_21 domain-containing protein. (334 aa)
	APZ42_021910	Steroid receptor seven-up. (262 aa)
	APZ42_021639	Chitin synthase 2. (876 aa)
	APZ42_021685	Tyrosine-protein kinase JAK1. (1217 aa)
	APZ42_017615	Cytochrome P450 315a1, mitochondrial; Belongs to the cytochrome P450 family. (491 aa)
	EOG090X0511	Putative Neurogenin-3. (297 aa)
	APZ42_020167	Methyltransf_21 domain-containing protein. (330 aa)
	APZ42_015224	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (717 aa)
	APZ42_012615	Rho-related GTP-binding protein RhoF. (223 aa)
	APZ42_011718	Cellular tumor antigen p53. (413 aa)
	APZ42_028914	Putative Receptor-type tyrosine-protein phosphatase N2. (940 aa)
	APZ42_028399	Chitin synthase variant. (1594 aa)
	EOG090X06V5	E3 ubiquitin-protein ligase Hakai. (351 aa)
	APZ42_032865	Integrin beta; Belongs to the integrin beta chain family. (810 aa)
	EOG090X01R1	Crooked neck protein 1. (743 aa)
	APZ42_030255	Integrin beta; Belongs to the integrin beta chain family. (791 aa)
	APZ42_033221	Putative Homeotic Antennapedia protein. (627 aa)
	APZ42_019011	ECT2 protein. (898 aa)
	APZ42_019355	Heat shock protein HSP 90-alpha. (788 aa)
	APZ42_032372	Receptor protein-tyrosine kinase. (1457 aa)
	APZ42_014947	Pre-mRNA-splicing factor SYF1. (851 aa)
	APZ42_011109	Putative Homeotic abdominal-B protein. (479 aa)
	APZ42_014678	DNA-binding protein SATB. (924 aa)
	APZ42_013806	Putative GA-binding protein alpha chain. (380 aa)
	APZ42_012646	Methyltransf_21 domain-containing protein. (262 aa)
	APZ42_012541	Putative Forkhead box protein K2. (157 aa)
	APZ42_012394	Palmitoleoyl-protein carboxylesterase NOTUM. (746 aa)
	APZ42_012361	Forkhead box protein K2. (306 aa)
	APZ42_012048	Mothers against decapentaplegic homolog. (536 aa)
	APZ42_011273	Laminin subunit gamma-3. (1735 aa)
	APZ42_011002	Putative T-box transcription factor TBX5-A. (631 aa)
	APZ42_004669	Ras GTP-binding protein Rho1. (41 aa)
	APZ42_002871	Uncharacterized protein. (135 aa)
	APZ42_002734	Pro-neuregulin-2, membrane-bound. (63 aa)
	APZ42_002304	Trachealess protein. (105 aa)
	APZ42_000652	Uncharacterized protein. (215 aa)
	APZ42_033226	Putative Buttonless. (187 aa)
	APZ42_033229	Putative Homeotic labial protein. (145 aa)
	APZ42_033218	Segmentation protein CAP'N'collar. (780 aa)
	APZ42_033023	Putative TGF-beta ligand glass bottom boat protein. (459 aa)
	APZ42_032195	Pro-neuregulin-2, membrane-bound-like protein. (466 aa)
	APZ42_030805	Methyltransf_21 domain-containing protein. (257 aa)
	APZ42_029354	Putative DNA-binding protein SATB1. (782 aa)
	APZ42_029542	Mast/stem cell growth factor receptor Kit. (903 aa)
	APZ42_029556	Viking. (1766 aa)
	APZ42_029559	Walrus. (337 aa)
	APZ42_028625	Uncharacterized protein. (1929 aa)
	APZ42_016653	Protein ecdysoneless. (639 aa)
	APZ42_018366	Uncharacterized protein. (625 aa)
	APZ42_018316	Tyrosine-protein kinase receptor. (1330 aa)
	APZ42_018949	Integrin beta; Belongs to the integrin beta chain family. (786 aa)
	APZ42_018678	Putative Myocyte-specific enhancer factor 2A. (384 aa)
	APZ42_020225	Receptor protein-tyrosine kinase. (1213 aa)
	APZ42_020156	Protein kinase domain-containing protein. (1515 aa)
	APZ42_020161	Putative Vascular endothelial growth factor receptor 1. (994 aa)
	APZ42_020116	Putative Receptor-type tyrosine-protein kinase FLT3. (791 aa)
	APZ42_020123	Protein kinase domain-containing protein. (468 aa)
	APZ42_020054	Putative Vascular endothelial growth factor receptor 3. (1011 aa)
	APZ42_020077	Methyltransf_21 domain-containing protein. (356 aa)
	APZ42_019844	Secreted protein acidic and rich in cysteine. (286 aa)
	APZ42_020456	UV radiation resistance-associated protein. (769 aa)
	APZ42_020568	Tyrosine-protein kinase. (587 aa)
	APZ42_022814	Methyltransf_21 domain-containing protein. (331 aa)
	APZ42_022799	Methyltransf_21 domain-containing protein. (374 aa)
	APZ42_020558	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. (416 aa)
	APZ42_019921	Protein kinase domain-containing protein. (749 aa)
	APZ42_020162	Putative Dual specificity protein phosphatase 10. (1162 aa)
	APZ42_021644	Uncharacterized protein. (1223 aa)
	APZ42_019958	Uncharacterized protein. (933 aa)
	APZ42_029557	Putative Collagen alpha-1(XXV) chain. (1782 aa)
	APZ42_032520	Uncharacterized protein. (1125 aa)
	APZ42_031074	Putative Shn zinc finger protein. (1642 aa)
	APZ42_024020	Uncharacterized protein. (943 aa)
	APZ42_026442	Protein crumbs. (2334 aa)
	APZ42_014363	Integrin beta; Belongs to the integrin beta chain family. (614 aa)
	APZ42_016151	E3 ubiquitin-protein ligase SMURF2. (690 aa)
	APZ42_014768	Dual specificity protein phosphatase 10. (552 aa)
	APZ42_016247	Uncharacterized protein. (789 aa)
	APZ42_033101	Homeobox Nkx-3.1-like protein. (436 aa)
	APZ42_028753	Putative Transcription factor odd-paired. (414 aa)
	APZ42_028159	SLIT protein. (1404 aa)
	APZ42_028343	Collagen alpha-2 chain. (1020 aa)
	APZ42_027909	EF-hand domain-containing protein. (527 aa)
	APZ42_026234	Integrin alpha-PS1; Belongs to the integrin alpha chain family. (999 aa)
	APZ42_025854	Uncharacterized protein. (884 aa)
	APZ42_025677	Fat cadherin-related tumor suppressor-like protein. (4893 aa)
	APZ42_019397	Unconventional myosin-Ih; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1017 aa)
	APZ42_024794	E3 ubiquitin-protein ligase SMURF2. (161 aa)
	APZ42_024747	Fragile X mental retardation Syndrome-related protein. (637 aa)
	EOG090X06HD	Peptide-N-asparagine amidase. (492 aa)
	APZ42_024351	Putative Homeotic Sex combs reduced protein. (345 aa)
	APZ42_024024	Bric-a-brac. (562 aa)
	APZ42_024303	Putative Inactive tyrosine-protein kinase 7. (1141 aa)
	APZ42_033994	Methyltransf_21 domain-containing protein. (316 aa)
	APZ42_023526	Laminin subunit gamma-3. (3391 aa)
	APZ42_013638	Kinase domain-containing protein, cytoplasmic. (323 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_000652	APZ42_004669	A0A164JH90	A0A164GWT3	Uncharacterized protein.	Ras GTP-binding protein Rho1.	0.466
APZ42_000652	APZ42_012615	A0A164JH90	A0A0P5KP21	Uncharacterized protein.	Rho-related GTP-binding protein RhoF.	0.466
APZ42_000652	APZ42_016151	A0A164JH90	A0A162NP38	Uncharacterized protein.	E3 ubiquitin-protein ligase SMURF2.	0.537
APZ42_000652	APZ42_018316	A0A164JH90	A0A164Z3T8	Uncharacterized protein.	Tyrosine-protein kinase receptor.	0.546
APZ42_000652	APZ42_020558	A0A164JH90	A0A162CBY6	Uncharacterized protein.	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.578
APZ42_000652	APZ42_020568	A0A164JH90	A0A164X7E9	Uncharacterized protein.	Tyrosine-protein kinase.	0.578
APZ42_000652	APZ42_024794	A0A164JH90	A0A164TRF7	Uncharacterized protein.	E3 ubiquitin-protein ligase SMURF2.	0.537
APZ42_002304	APZ42_019355	A0A164ICX5	A0A0P5Z7H7	Trachealess protein.	Heat shock protein HSP 90-alpha.	0.401
APZ42_002734	APZ42_004669	A0A164I2R4	A0A164GWT3	Pro-neuregulin-2, membrane-bound.	Ras GTP-binding protein Rho1.	0.581
APZ42_002734	APZ42_012615	A0A164I2R4	A0A0P5KP21	Pro-neuregulin-2, membrane-bound.	Rho-related GTP-binding protein RhoF.	0.581
APZ42_002734	APZ42_013638	A0A164I2R4	A0A0P4XA98	Pro-neuregulin-2, membrane-bound.	Kinase domain-containing protein, cytoplasmic.	0.462
APZ42_002734	APZ42_014363	A0A164I2R4	A0A162EJD3	Pro-neuregulin-2, membrane-bound.	Integrin beta; Belongs to the integrin beta chain family.	0.547
APZ42_002734	APZ42_018949	A0A164I2R4	A0A164YYE1	Pro-neuregulin-2, membrane-bound.	Integrin beta; Belongs to the integrin beta chain family.	0.547
APZ42_002734	APZ42_026234	A0A164I2R4	A0A164SB27	Pro-neuregulin-2, membrane-bound.	Integrin alpha-PS1; Belongs to the integrin alpha chain family.	0.543
APZ42_002734	APZ42_030255	A0A164I2R4	A0A0P5XYV6	Pro-neuregulin-2, membrane-bound.	Integrin beta; Belongs to the integrin beta chain family.	0.547
APZ42_002734	APZ42_032865	A0A164I2R4	A0A0P5XKW0	Pro-neuregulin-2, membrane-bound.	Integrin beta; Belongs to the integrin beta chain family.	0.547
APZ42_002871	APZ42_018678	A0A164HZG8	A0A164YRC6	Uncharacterized protein.	Putative Myocyte-specific enhancer factor 2A.	0.622
APZ42_002871	EOG090X0511	A0A164HZG8	A0A0P5EJ98	Uncharacterized protein.	Putative Neurogenin-3.	0.823
APZ42_004669	APZ42_000652	A0A164GWT3	A0A164JH90	Ras GTP-binding protein Rho1.	Uncharacterized protein.	0.466
APZ42_004669	APZ42_002734	A0A164GWT3	A0A164I2R4	Ras GTP-binding protein Rho1.	Pro-neuregulin-2, membrane-bound.	0.581