(42 nodes) Homeostasis of number of cells network (Daphnia magna)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	APZ42_020225	Receptor protein-tyrosine kinase. (1213 aa)
	APZ42_014767	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma. (433 aa)
	APZ42_020419	TSC22 domain family, member. (819 aa)
	APZ42_022795	Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. (283 aa)
	APZ42_011346	Macrophage erythroblast attacher. (447 aa)
	APZ42_020472	Apoptosis regulator BAX. (210 aa)
	APZ42_022685	Tuberous sclerosis gene product-1. (1225 aa)
	APZ42_021015	Autophagy-related protein 16-1. (378 aa)
	APZ42_028293	Putative Cysteine-rich protein 2-binding protein. (517 aa)
	EOG090X03TK	E3 ubiquitin-protein ligase synoviolin. (569 aa)
	APZ42_016559	Hairless. (452 aa)
	APZ42_016764	Uncharacterized protein. (560 aa)
	APZ42_023061	Serine/threonine protein kinase TAO1 alpha. (942 aa)
	APZ42_011329	HEAT shock 70 kDa protein cognate 4; Belongs to the heat shock protein 70 family. (659 aa)
	APZ42_022687	Dual specificity mitogen-activated protein kinase kinase. (803 aa)
	APZ42_032372	Receptor protein-tyrosine kinase. (1457 aa)
	APZ42_015159	Ras-related protein Rab-19. (217 aa)
	APZ42_019921	Protein kinase domain-containing protein. (749 aa)
	APZ42_019958	Uncharacterized protein. (933 aa)
	APZ42_011613	Putative Zinc finger FYVE domain-containing protein. (929 aa)
	APZ42_025710	OCIA domain-containing protein 1. (260 aa)
	APZ42_015309	Putative X-box-binding protein. (345 aa)
	APZ42_014551	Relaxin receptor 1. (1633 aa)
	APZ42_013130	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family. (1116 aa)
	APZ42_013134	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit Delta; Belongs to the PI3/PI4-kinase family. (658 aa)
	APZ42_010920	Nuclear receptor-binding protein. (552 aa)
	APZ42_000652	Uncharacterized protein. (215 aa)
	APZ42_033218	Segmentation protein CAP'N'collar. (780 aa)
	APZ42_032632	Follistatin-related protein 1. (401 aa)
	APZ42_030076	ATP-dependent Helicase brm. (1476 aa)
	APZ42_029542	Mast/stem cell growth factor receptor Kit. (903 aa)
	APZ42_026391	Tyrosine-protein phosphatase Lar. (1106 aa)
	APZ42_025854	Uncharacterized protein. (884 aa)
	APZ42_024303	Putative Inactive tyrosine-protein kinase 7. (1141 aa)
	APZ42_023352	Tyrosine-protein phosphatase Lar. (544 aa)
	APZ42_021685	Tyrosine-protein kinase JAK1. (1217 aa)
	APZ42_020991	Autophagy-related protein 16-1. (212 aa)
	APZ42_020054	Putative Vascular endothelial growth factor receptor 3. (1011 aa)
	APZ42_020123	Protein kinase domain-containing protein. (468 aa)
	APZ42_020116	Putative Receptor-type tyrosine-protein kinase FLT3. (791 aa)
	APZ42_020161	Putative Vascular endothelial growth factor receptor 1. (994 aa)
	APZ42_020156	Protein kinase domain-containing protein. (1515 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_000652	APZ42_013130	A0A164JH90	A0A162R1L1	Uncharacterized protein.	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family.	0.607
APZ42_000652	APZ42_013134	A0A164JH90	A0A162R1M2	Uncharacterized protein.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit Delta; Belongs to the PI3/PI4-kinase family.	0.607
APZ42_010920	APZ42_020419	A0A162TAP3	A0A0N8CFX1	Nuclear receptor-binding protein.	TSC22 domain family, member.	0.771
APZ42_011329	APZ42_015309	A0A0P5ZG64	A0A162PCP8	HEAT shock 70 kDa protein cognate 4; Belongs to the heat shock protein 70 family.	Putative X-box-binding protein.	0.698
APZ42_011329	APZ42_022685	A0A0P5ZG64	A0A0P4YL26	HEAT shock 70 kDa protein cognate 4; Belongs to the heat shock protein 70 family.	Tuberous sclerosis gene product-1.	0.844
APZ42_011329	APZ42_023352	A0A0P5ZG64	A0A164V102	HEAT shock 70 kDa protein cognate 4; Belongs to the heat shock protein 70 family.	Tyrosine-protein phosphatase Lar.	0.561
APZ42_011329	APZ42_026391	A0A0P5ZG64	A0A164S6S9	HEAT shock 70 kDa protein cognate 4; Belongs to the heat shock protein 70 family.	Tyrosine-protein phosphatase Lar.	0.561
APZ42_011329	EOG090X03TK	A0A0P5ZG64	A0A0P5S985	HEAT shock 70 kDa protein cognate 4; Belongs to the heat shock protein 70 family.	E3 ubiquitin-protein ligase synoviolin.	0.826
APZ42_013130	APZ42_000652	A0A162R1L1	A0A164JH90	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.607
APZ42_013130	APZ42_014551	A0A162R1L1	A0A162PR01	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family.	Relaxin receptor 1.	0.504
APZ42_013130	APZ42_019921	A0A162R1L1	A0A162CDQ9	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family.	Protein kinase domain-containing protein.	0.607
APZ42_013130	APZ42_019958	A0A162R1L1	A0A162CMM2	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.607
APZ42_013130	APZ42_020054	A0A162R1L1	A0A164XZF9	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family.	Putative Vascular endothelial growth factor receptor 3.	0.607
APZ42_013130	APZ42_020116	A0A162R1L1	A0A164Y0N9	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family.	Putative Receptor-type tyrosine-protein kinase FLT3.	0.607
APZ42_013130	APZ42_020123	A0A162R1L1	A0A164Y074	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family.	Protein kinase domain-containing protein.	0.607
APZ42_013130	APZ42_020156	A0A162R1L1	A0A164Y2V3	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family.	Protein kinase domain-containing protein.	0.607
APZ42_013130	APZ42_020161	A0A162R1L1	A0A164Y2T4	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family.	Putative Vascular endothelial growth factor receptor 1.	0.607
APZ42_013130	APZ42_020225	A0A162R1L1	A0A164Y3U6	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family.	Receptor protein-tyrosine kinase.	0.607
APZ42_013130	APZ42_021685	A0A162R1L1	A0A164WH24	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family.	Tyrosine-protein kinase JAK1.	0.607
APZ42_013130	APZ42_023061	A0A162R1L1	A0A0P5YYD0	Phosphatidylinositol 3-kinase catalytic subunit type 3; Belongs to the PI3/PI4-kinase family.	Serine/threonine protein kinase TAO1 alpha.	0.489