(42 nodes) Regulation of protein secretion network (Daphnia magna)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	APZ42_029501	Adiponectin receptor protein. (464 aa)
	APZ42_020747	CDV3 B protein. (270 aa)
	APZ42_016463	TBC1 domain family member. (353 aa)
	APZ42_011518	Mitogen-activated protein kinase. (654 aa)
	APZ42_033994	Methyltransf_21 domain-containing protein. (316 aa)
	APZ42_022814	Methyltransf_21 domain-containing protein. (331 aa)
	APZ42_020167	Methyltransf_21 domain-containing protein. (330 aa)
	EOG090X0GN3	Sorting nexin-12. (161 aa)
	APZ42_011302	Ras-related protein Rab-23. (251 aa)
	EOG090X00QE	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (811 aa)
	APZ42_018524	60S ribosomal export protein NMD3. (541 aa)
	APZ42_020989	Transmembrane 7 superfamily member 3. (555 aa)
	APZ42_016710	Serine/threonine-protein kinase pim-2; Belongs to the protein kinase superfamily. (404 aa)
	APZ42_012144	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (621 aa)
	APZ42_017443	Rhomboid 5 (RHBDF2), mRNA protein. (1665 aa)
	APZ42_030785	Progestin and adipoQ receptor family member 4. (383 aa)
	APZ42_032653	Protein FAM92A1. (319 aa)
	APZ42_022799	Methyltransf_21 domain-containing protein. (374 aa)
	APZ42_018480	Ubiquinol-cytochrome-c reductase complex assembly factor 2. (172 aa)
	APZ42_026385	ALG-2 interacting protein X. (1756 aa)
	APZ42_014095	Protein canopy. (215 aa)
	APZ42_013357	Gamma-aminobutyric acid type B receptor subunit 1. (1581 aa)
	APZ42_012646	Methyltransf_21 domain-containing protein. (262 aa)
	APZ42_030805	Methyltransf_21 domain-containing protein. (257 aa)
	APZ42_030520	Syntaxin-binding 5-like protein. (1349 aa)
	APZ42_030635	Secretion-regulating guanine nucleotide exchange factor. (301 aa)
	APZ42_028575	Flotillin-2; Belongs to the band 7/mec-2 family. Flotillin subfamily. (424 aa)
	APZ42_027103	PRKCA-binding protein. (441 aa)
	APZ42_026329	DnaJ subfamily C member 1. (491 aa)
	APZ42_022288	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (227 aa)
	APZ42_022510	Hepatocyte growth factor-regulated tyrosine kinase substrate. (706 aa)
	APZ42_022759	Uncharacterized protein. (259 aa)
	APZ42_022813	Methyltransf_21 domain-containing protein. (334 aa)
	APZ42_021596	Vacuolar protein sorting-associated protein 18. (921 aa)
	APZ42_020077	Methyltransf_21 domain-containing protein. (356 aa)
	APZ42_019193	Putative A disintegrin and metalloproteinase with thrombospondin motifs 3. (702 aa)
	APZ42_017788	Syntaxin-binding 5-like protein. (276 aa)
	APZ42_017521	Rho GTPase-activating protein 92B. (867 aa)
	APZ42_016715	Serine/threonine-protein kinase pim-2; Belongs to the protein kinase superfamily. (497 aa)
	APZ42_016906	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (205 aa)
	APZ42_016348	Uncharacterized protein; Belongs to the peptidase S1 family. (1511 aa)
	APZ42_016378	Peptidase S1 domain-containing protein. (217 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_011518	APZ42_016710	A0A0P4XMK0	A0A0P5UC66	Mitogen-activated protein kinase.	Serine/threonine-protein kinase pim-2; Belongs to the protein kinase superfamily.	0.679
APZ42_011518	APZ42_016715	A0A0P4XMK0	A0A165A3W6	Mitogen-activated protein kinase.	Serine/threonine-protein kinase pim-2; Belongs to the protein kinase superfamily.	0.679
APZ42_011518	APZ42_026385	A0A0P4XMK0	A0A162DAZ1	Mitogen-activated protein kinase.	ALG-2 interacting protein X.	0.856
APZ42_016710	APZ42_011518	A0A0P5UC66	A0A0P4XMK0	Serine/threonine-protein kinase pim-2; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.679
APZ42_016710	EOG090X00QE	A0A0P5UC66	A0A0P5P8Q8	Serine/threonine-protein kinase pim-2; Belongs to the protein kinase superfamily.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.422
APZ42_016715	APZ42_011518	A0A165A3W6	A0A0P4XMK0	Serine/threonine-protein kinase pim-2; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.679
APZ42_016715	EOG090X00QE	A0A165A3W6	A0A0P5P8Q8	Serine/threonine-protein kinase pim-2; Belongs to the protein kinase superfamily.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.422
APZ42_018524	EOG090X00QE	A0A0P5T322	A0A0P5P8Q8	60S ribosomal export protein NMD3.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.856
APZ42_018524	EOG090X0GN3	A0A0P5T322	A0A0P5FHN5	60S ribosomal export protein NMD3.	Sorting nexin-12.	0.987
APZ42_021596	EOG090X00QE	A0A164WJA5	A0A0P5P8Q8	Vacuolar protein sorting-associated protein 18.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.557
APZ42_022510	APZ42_026385	A0A164VLJ1	A0A162DAZ1	Hepatocyte growth factor-regulated tyrosine kinase substrate.	ALG-2 interacting protein X.	0.830
APZ42_022510	EOG090X00QE	A0A164VLJ1	A0A0P5P8Q8	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.657
APZ42_022510	EOG090X0GN3	A0A164VLJ1	A0A0P5FHN5	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Sorting nexin-12.	0.657
APZ42_026385	APZ42_011518	A0A162DAZ1	A0A0P4XMK0	ALG-2 interacting protein X.	Mitogen-activated protein kinase.	0.856
APZ42_026385	APZ42_022510	A0A162DAZ1	A0A164VLJ1	ALG-2 interacting protein X.	Hepatocyte growth factor-regulated tyrosine kinase substrate.	0.830
EOG090X00QE	APZ42_016710	A0A0P5P8Q8	A0A0P5UC66	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	Serine/threonine-protein kinase pim-2; Belongs to the protein kinase superfamily.	0.422
EOG090X00QE	APZ42_016715	A0A0P5P8Q8	A0A165A3W6	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	Serine/threonine-protein kinase pim-2; Belongs to the protein kinase superfamily.	0.422
EOG090X00QE	APZ42_018524	A0A0P5P8Q8	A0A0P5T322	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	60S ribosomal export protein NMD3.	0.856
EOG090X00QE	APZ42_021596	A0A0P5P8Q8	A0A164WJA5	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	Vacuolar protein sorting-associated protein 18.	0.557
EOG090X00QE	APZ42_022510	A0A0P5P8Q8	A0A164VLJ1	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	Hepatocyte growth factor-regulated tyrosine kinase substrate.	0.657