(35 nodes) Defense response to Gram-negative bacterium network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_025305	HBS1-like protein. (691 aa)
	APZ42_015155	E3 SUMO-protein ligase PIAS1. (674 aa)
	APZ42_018629	Beadex/dlmo protein. (540 aa)
	APZ42_023485	Putative Ankyrin repeat domain-containing protein 19. (1016 aa)
	APZ42_028583	Myotubularin-related protein 10-B. (923 aa)
	APZ42_018630	Spaetzle. (410 aa)
	APZ42_015983	Programmed cell death protein 5. (127 aa)
	EOG090X06NC	Histone acetyltransferase type B catalytic subunit. (408 aa)
	APZ42_023484	S-adenosylmethionine decarboxylase proenzyme. (423 aa)
	APZ42_019396	Transport protein Sec31A. (1244 aa)
	APZ42_011300	Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (632 aa)
	APZ42_029681	WD repeat-containing protein 55. (519 aa)
	APZ42_026294	Putative 28S rRNA (Cytosine-C(5))-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (447 aa)
	APZ42_018538	Nuclear receptor subfamily 0 group B member 2. (590 aa)
	APZ42_011136	NTF2-related export protein 1. (137 aa)
	APZ42_023707	Transmembrane protein 120A. (409 aa)
	APZ42_025596	Ubiquitin carboxyl-terminal hydrolase FAF-X; Belongs to the peptidase C19 family. (2353 aa)
	APZ42_016016	Receptor-interacting serine/threonine-protein kinase. (216 aa)
	APZ42_014774	Threonine aspartase 1. (337 aa)
	APZ42_014550	Protein sickie-like protein. (1933 aa)
	APZ42_010849	Akirin. (252 aa)
	EOG090X048D	Beclin-1-like protein. (441 aa)
	APZ42_033777	TNF receptor-associated factor 4. (359 aa)
	APZ42_032152	Protein eiger-like protein; Belongs to the tumor necrosis factor family. (652 aa)
	APZ42_029493	c-Myc promoter-binding protein. (1859 aa)
	APZ42_028279	Laminin subunit beta-1. (1611 aa)
	APZ42_025677	Fat cadherin-related tumor suppressor-like protein. (4893 aa)
	APZ42_025177	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (487 aa)
	APZ42_022190	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (207 aa)
	APZ42_021802	Tumor suppressor candidate 2. (95 aa)
	APZ42_020436	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (845 aa)
	APZ42_017870	LysM domain-containing protein. (1111 aa)
	APZ42_017109	Protein NUCB1. (544 aa)
	APZ42_016797	Putative E3 ubiquitin-protein ligase RNF31. (2277 aa)
	APZ42_016486	Mitochondrial thiamine pyrophosphate carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (352 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_014550	APZ42_023485	A0A162PPX1	A0A0P5E9N4	Protein sickie-like protein.	Putative Ankyrin repeat domain-containing protein 19.	0.564
APZ42_015155	APZ42_025177	A0A0N8DA50	A0A164TCX9	E3 SUMO-protein ligase PIAS1.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.521
APZ42_015983	EOG090X048D	A0A0P5TI46	A0A164I960	Programmed cell death protein 5.	Beclin-1-like protein.	0.502
APZ42_016016	APZ42_018630	A0A162NIB1	A0A0P5T7D7	Receptor-interacting serine/threonine-protein kinase.	Spaetzle.	0.497
APZ42_016016	APZ42_023485	A0A162NIB1	A0A0P5E9N4	Receptor-interacting serine/threonine-protein kinase.	Putative Ankyrin repeat domain-containing protein 19.	0.832
APZ42_016797	APZ42_033777	A0A165A6A1	A0A164KVP4	Putative E3 ubiquitin-protein ligase RNF31.	TNF receptor-associated factor 4.	0.578
APZ42_018630	APZ42_016016	A0A0P5T7D7	A0A162NIB1	Spaetzle.	Receptor-interacting serine/threonine-protein kinase.	0.497
APZ42_018630	APZ42_023485	A0A0P5T7D7	A0A0P5E9N4	Spaetzle.	Putative Ankyrin repeat domain-containing protein 19.	0.481
APZ42_020436	APZ42_023485	A0A164XHS0	A0A0P5E9N4	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	Putative Ankyrin repeat domain-containing protein 19.	0.525
APZ42_020436	APZ42_025177	A0A164XHS0	A0A164TCX9	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.552
APZ42_023485	APZ42_014550	A0A0P5E9N4	A0A162PPX1	Putative Ankyrin repeat domain-containing protein 19.	Protein sickie-like protein.	0.564
APZ42_023485	APZ42_016016	A0A0P5E9N4	A0A162NIB1	Putative Ankyrin repeat domain-containing protein 19.	Receptor-interacting serine/threonine-protein kinase.	0.832
APZ42_023485	APZ42_018630	A0A0P5E9N4	A0A0P5T7D7	Putative Ankyrin repeat domain-containing protein 19.	Spaetzle.	0.481
APZ42_023485	APZ42_020436	A0A0P5E9N4	A0A164XHS0	Putative Ankyrin repeat domain-containing protein 19.	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.525
APZ42_023485	APZ42_028279	A0A0P5E9N4	A0A164QNN0	Putative Ankyrin repeat domain-containing protein 19.	Laminin subunit beta-1.	0.454
APZ42_023485	APZ42_028583	A0A0P5E9N4	A0A0P5PPZ0	Putative Ankyrin repeat domain-containing protein 19.	Myotubularin-related protein 10-B.	0.417
APZ42_023485	APZ42_033777	A0A0P5E9N4	A0A164KVP4	Putative Ankyrin repeat domain-containing protein 19.	TNF receptor-associated factor 4.	0.524
APZ42_025177	APZ42_015155	A0A164TCX9	A0A0N8DA50	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	E3 SUMO-protein ligase PIAS1.	0.521
APZ42_025177	APZ42_020436	A0A164TCX9	A0A164XHS0	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.552
APZ42_028279	APZ42_023485	A0A164QNN0	A0A0P5E9N4	Laminin subunit beta-1.	Putative Ankyrin repeat domain-containing protein 19.	0.454