(28 nodes) Canonical Wnt signaling pathway network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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Predicted Interactions

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Your Input:
	wg	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (379 aa)
	APZ42_020297	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (323 aa)
	APZ42_020404	Wnt-receptor frizzled variant 1-like protein; Belongs to the G-protein coupled receptor Fz/Smo family. (636 aa)
	APZ42_014989	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (414 aa)
	APZ42_025753	Low-density lipoprotein receptor-related protein 6. (1758 aa)
	APZ42_013673	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (397 aa)
	APZ42_016802	Secreted frizzled-related protein 2. (394 aa)
	APZ42_014987	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (558 aa)
	APZ42_026322	Putative Segment polarity protein dishevelled. (699 aa)
	APZ42_002723	Putative Transcription coactivator armadillo. (248 aa)
	APZ42_014994	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (272 aa)
	APZ42_004666	CTNNB1_binding domain-containing protein. (94 aa)
	APZ42_004512	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (124 aa)
	APZ42_034413	NTR domain-containing protein. (170 aa)
	APZ42_030850	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (942 aa)
	APZ42_024581	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (427 aa)
	APZ42_024159	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
	APZ42_023676	Putative Transcription coactivator armadillo. (548 aa)
	APZ42_022951	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (207 aa)
	APZ42_022110	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (344 aa)
	APZ42_021749	PHD-type domain-containing protein. (301 aa)
	APZ42_021477	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (185 aa)
	APZ42_020570	Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (713 aa)
	APZ42_018318	DIX domain-containing protein. (339 aa)
	APZ42_018325	Dixin. (459 aa)
	APZ42_018371	HMG box domain-containing protein. (145 aa)
	APZ42_018366	Uncharacterized protein. (625 aa)
	APZ42_016562	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (319 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_002723	APZ42_004512	A0A162CY37	A0A164H0C2	Putative Transcription coactivator armadillo.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.474
APZ42_002723	APZ42_004666	A0A162CY37	A0A164GWW0	Putative Transcription coactivator armadillo.	CTNNB1_binding domain-containing protein.	0.905
APZ42_002723	APZ42_013673	A0A162CY37	A0A0P4ZIZ1	Putative Transcription coactivator armadillo.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.474
APZ42_002723	APZ42_014994	A0A162CY37	A0A162P3P8	Putative Transcription coactivator armadillo.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.474
APZ42_002723	APZ42_016562	A0A162CY37	A0A165AHN1	Putative Transcription coactivator armadillo.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.474
APZ42_002723	APZ42_016802	A0A162CY37	A0A0P5AXX5	Putative Transcription coactivator armadillo.	Secreted frizzled-related protein 2.	0.613
APZ42_002723	APZ42_018366	A0A162CY37	A0A164Z5Q8	Putative Transcription coactivator armadillo.	Uncharacterized protein.	0.928
APZ42_002723	APZ42_018371	A0A162CY37	A0A164Z5P2	Putative Transcription coactivator armadillo.	HMG box domain-containing protein.	0.905
APZ42_002723	APZ42_020297	A0A162CY37	A0A0N7ZKS5	Putative Transcription coactivator armadillo.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.474
APZ42_002723	APZ42_020404	A0A162CY37	A0A0N8BXH8	Putative Transcription coactivator armadillo.	Wnt-receptor frizzled variant 1-like protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.613
APZ42_002723	APZ42_020570	A0A162CY37	A0A164X7T0	Putative Transcription coactivator armadillo.	Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family.	0.613
APZ42_002723	APZ42_021477	A0A162CY37	A0A164WMH6	Putative Transcription coactivator armadillo.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.474
APZ42_002723	APZ42_021749	A0A162CY37	A0A164WHM8	Putative Transcription coactivator armadillo.	PHD-type domain-containing protein.	0.872
APZ42_002723	APZ42_022110	A0A162CY37	A0A164W1Y6	Putative Transcription coactivator armadillo.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.474
APZ42_002723	APZ42_022951	A0A162CY37	A0A164VB60	Putative Transcription coactivator armadillo.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.682
APZ42_002723	APZ42_023676	A0A162CY37	A0A164UP18	Putative Transcription coactivator armadillo.	Putative Transcription coactivator armadillo.	0.925
APZ42_002723	APZ42_024159	A0A162CY37	A0A164UHN6	Putative Transcription coactivator armadillo.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.474
APZ42_002723	APZ42_024581	A0A162CY37	A0A164TZY3	Putative Transcription coactivator armadillo.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.474
APZ42_002723	APZ42_025753	A0A162CY37	A0A0P4YGB1	Putative Transcription coactivator armadillo.	Low-density lipoprotein receptor-related protein 6.	0.538
APZ42_002723	APZ42_026322	A0A162CY37	A0A0P5YKA8	Putative Transcription coactivator armadillo.	Putative Segment polarity protein dishevelled.	0.874