(44 nodes) Intracellular protein transmembrane transport network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_030851	Ubiquitin-protein e3 ligase. (394 aa)
	APZ42_017064	RING-type domain-containing protein. (252 aa)
	APZ42_017079	Mitochondrial import receptor subunit TOM40B. (306 aa)
	APZ42_017849	HEAT shock 70 kDa protein cognate 5; Belongs to the heat shock protein 70 family. (613 aa)
	APZ42_020059	Peroxisome biogenesis factor 10. (229 aa)
	APZ42_021693	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (421 aa)
	APZ42_022619	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (219 aa)
	APZ42_022658	RING-type domain-containing protein. (165 aa)
	APZ42_026298	WD_REPEATS_REGION domain-containing protein. (317 aa)
	APZ42_026237	Peroxisome biogenesis factor 1. (998 aa)
	APZ42_027255	Peroxin 6. (815 aa)
	APZ42_030558	Mitochondrial import receptor subunit TOM7. (55 aa)
	APZ42_030525	Peroxin 2. (377 aa)
	APZ42_030856	RING-type domain-containing protein. (240 aa)
	APZ42_033049	Putative Reactive oxygen species modulator 1. (46 aa)
	APZ42_033479	Mitochondrial import receptor subunit TOM22. (178 aa)
	APZ42_033751	RING-type domain-containing protein. (234 aa)
	APZ42_002135	HEAT shock 70 kDa protein cognate 5. (129 aa)
	APZ42_004988	Mitochondrial import inner membrane translocase subunit Tim16. (104 aa)
	APZ42_008330	Translocation protein SEC62. (111 aa)
	APZ42_012465	Mitochondrial import receptor subunit TOM70. (593 aa)
	EOG090X0RAK	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (100 aa)
	APZ42_014457	Putative Translocation protein SEC62. (182 aa)
	EOG090X0I05	TIM21 protein. (211 aa)
	APZ42_016068	RING finger 141-like protein. (333 aa)
	EOG090X03AJ	DnaJ subfamily C member 11. (550 aa)
	APZ42_024125	Ubiquitin-protein e3 ligase. (238 aa)
	APZ42_021448	Peroxisomal membrane protein PEX14. (313 aa)
	EOG090X03VW	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (506 aa)
	APZ42_034295	60 kDa heat shock protein, mitochondrial; Belongs to the chaperonin (HSP60) family. (576 aa)
	APZ42_023953	Translocation protein SEC63. (751 aa)
	APZ42_022336	Nucleotide exchange factor SIL1. (482 aa)
	APZ42_017872	Mitochondrial import inner membrane translocase subunit Tim17-A. (163 aa)
	EOG090X03O4	Transport protein Sec61 subunit alpha 1. (476 aa)
	APZ42_011419	Peroxisomal membrane protein PEX13. (361 aa)
	APZ42_032867	C2 domain-containing protein 5. (1021 aa)
	APZ42_034168	Mitochondrial import receptor subunit TOM20. (153 aa)
	APZ42_022849	Apoptosis-inducing factor 1, mitochondrial. (693 aa)
	APZ42_026823	Protein FAM185A. (381 aa)
	APZ42_033070	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (431 aa)
	APZ42_028073	Peroxisomal targeting Signal 1 receptor. (623 aa)
	APZ42_030848	Putative E3 ubiquitin-protein ligase Topors. (539 aa)
	EOG090X0MNL	Mitochondrial import inner membrane translocase subunit TIM14. (117 aa)
	EOG090X0AIN	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family. (301 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_002135	APZ42_004988	A0A164IHF4	A0A164GQJ6	HEAT shock 70 kDa protein cognate 5.	Mitochondrial import inner membrane translocase subunit Tim16.	0.744
APZ42_002135	APZ42_012465	A0A164IHF4	A0A162RV77	HEAT shock 70 kDa protein cognate 5.	Mitochondrial import receptor subunit TOM70.	0.607
APZ42_002135	APZ42_017079	A0A164IHF4	A0A165A1G4	HEAT shock 70 kDa protein cognate 5.	Mitochondrial import receptor subunit TOM40B.	0.523
APZ42_002135	APZ42_017872	A0A164IHF4	A0A0P5R5N0	HEAT shock 70 kDa protein cognate 5.	Mitochondrial import inner membrane translocase subunit Tim17-A.	0.915
APZ42_002135	APZ42_021693	A0A164IHF4	A0A164WFU6	HEAT shock 70 kDa protein cognate 5.	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.577
APZ42_002135	APZ42_022336	A0A164IHF4	A0A0P5TFK5	HEAT shock 70 kDa protein cognate 5.	Nucleotide exchange factor SIL1.	0.790
APZ42_002135	APZ42_022619	A0A164IHF4	A0A164VPI4	HEAT shock 70 kDa protein cognate 5.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.988
APZ42_002135	APZ42_023953	A0A164IHF4	A0A0P5VMU2	HEAT shock 70 kDa protein cognate 5.	Translocation protein SEC63.	0.718
APZ42_002135	APZ42_033070	A0A164IHF4	A0A0N8DF35	HEAT shock 70 kDa protein cognate 5.	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.	0.972
APZ42_002135	APZ42_033479	A0A164IHF4	A0A164L1U4	HEAT shock 70 kDa protein cognate 5.	Mitochondrial import receptor subunit TOM22.	0.496
APZ42_002135	APZ42_034168	A0A164IHF4	A0A0P5E8L1	HEAT shock 70 kDa protein cognate 5.	Mitochondrial import receptor subunit TOM20.	0.439
APZ42_002135	APZ42_034295	A0A164IHF4	A0A0P5WDI2	HEAT shock 70 kDa protein cognate 5.	60 kDa heat shock protein, mitochondrial; Belongs to the chaperonin (HSP60) family.	0.984
APZ42_002135	EOG090X03AJ	A0A164IHF4	A0A0P6I1W9	HEAT shock 70 kDa protein cognate 5.	DnaJ subfamily C member 11.	0.826
APZ42_002135	EOG090X0I05	A0A164IHF4	A0A162P6A6	HEAT shock 70 kDa protein cognate 5.	TIM21 protein.	0.424
APZ42_002135	EOG090X0MNL	A0A164IHF4	A0A0N8BWH6	HEAT shock 70 kDa protein cognate 5.	Mitochondrial import inner membrane translocase subunit TIM14.	0.953
APZ42_004988	APZ42_002135	A0A164GQJ6	A0A164IHF4	Mitochondrial import inner membrane translocase subunit Tim16.	HEAT shock 70 kDa protein cognate 5.	0.744
APZ42_004988	APZ42_012465	A0A164GQJ6	A0A162RV77	Mitochondrial import inner membrane translocase subunit Tim16.	Mitochondrial import receptor subunit TOM70.	0.553
APZ42_004988	APZ42_017079	A0A164GQJ6	A0A165A1G4	Mitochondrial import inner membrane translocase subunit Tim16.	Mitochondrial import receptor subunit TOM40B.	0.622
APZ42_004988	APZ42_017849	A0A164GQJ6	A0A164ZJ03	Mitochondrial import inner membrane translocase subunit Tim16.	HEAT shock 70 kDa protein cognate 5; Belongs to the heat shock protein 70 family.	0.744
APZ42_004988	APZ42_017872	A0A164GQJ6	A0A0P5R5N0	Mitochondrial import inner membrane translocase subunit Tim16.	Mitochondrial import inner membrane translocase subunit Tim17-A.	0.982