(34 nodes) Neuron cellular homeostasis network (Daphnia magna)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	APZ42_013662	Glucosylceramidase. (538 aa)
	APZ42_010947	5'-AMP-activated protein kinase subunit beta-1. (274 aa)
	APZ42_034380	F-box/WD repeat-containing protein TBL1XR1. (492 aa)
	APZ42_014233	Long-chain-fatty-acid--CoA ligase 5. (696 aa)
	APZ42_015851	Wd-repeat protein. (392 aa)
	APZ42_011645	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1220 aa)
	APZ42_027637	Glucosylceramidase. (519 aa)
	APZ42_015097	Glucose-dependent insulinotropic receptor; Belongs to the G-protein coupled receptor 1 family. (589 aa)
	APZ42_031956	F-box/WD repeat-containing TBL1XR1-like protein. (735 aa)
	APZ42_015782	Long-chain-fatty-acid--CoA ligase bubblegum-like protein. (895 aa)
	APZ42_011838	Monocarboxylate transporter 9. (536 aa)
	APZ42_032336	Ankyrin repeat and SOCS box protein 3. (2634 aa)
	APZ42_025860	Torsin-like protein. (351 aa)
	APZ42_018957	F-box/WD repeat-containing TBL1XR1-like protein. (373 aa)
	EOG090X0F26	Mesencephalic astrocyte-derived neurotrophic factor. (172 aa)
	APZ42_003663	Uncharacterized protein. (76 aa)
	APZ42_016259	Putative Class A rhodopsin G-protein-coupled receptor gprdop2. (421 aa)
	APZ42_016678	Calbindin-32. (119 aa)
	APZ42_020876	Putative Class A rhodopsin G-protein-coupled receptor gprdop2. (315 aa)
	APZ42_023975	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (409 aa)
	APZ42_026543	Peroxisome proliferator-activated receptor gamma coactivator-related-like protein. (511 aa)
	APZ42_029725	Calbindin-32. (228 aa)
	APZ42_030081	Cysteine string protein. (85 aa)
	APZ42_031212	PERQ amino acid-rich with GYF domain-containing protein. (275 aa)
	APZ42_032152	Protein eiger-like protein; Belongs to the tumor necrosis factor family. (652 aa)
	APZ42_032338	Uncharacterized protein. (1812 aa)
	APZ42_001519	Long-chain-fatty-acid--CoA ligase. (156 aa)
	APZ42_001966	Class A rhodopsin G-protein-coupled receptor gprdop2. (104 aa)
	APZ42_011596	Syntaxin-17. (298 aa)
	APZ42_013663	Glucosylceramidase. (516 aa)
	APZ42_014234	Long-chain-fatty-acid--CoA ligase 5. (696 aa)
	APZ42_014229	Long-chain-fatty-acid--CoA ligase. (321 aa)
	APZ42_016062	Putative wd-repeat protein. (376 aa)
	APZ42_015896	WD repeat-containing protein 53. (396 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_001519	APZ42_014229	A0A164IXF7	A0A162Q5U9	Long-chain-fatty-acid--CoA ligase.	Long-chain-fatty-acid--CoA ligase.	0.941
APZ42_001519	APZ42_015782	A0A164IXF7	A0A0P6DJ83	Long-chain-fatty-acid--CoA ligase.	Long-chain-fatty-acid--CoA ligase bubblegum-like protein.	0.760
APZ42_001966	APZ42_011645	A0A164ILW2	A0A0P5TMV7	Class A rhodopsin G-protein-coupled receptor gprdop2.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.516
APZ42_001966	APZ42_015097	A0A164ILW2	A0A0P5YZI9	Class A rhodopsin G-protein-coupled receptor gprdop2.	Glucose-dependent insulinotropic receptor; Belongs to the G-protein coupled receptor 1 family.	0.835
APZ42_001966	APZ42_016259	A0A164ILW2	A0A165AIN5	Class A rhodopsin G-protein-coupled receptor gprdop2.	Putative Class A rhodopsin G-protein-coupled receptor gprdop2.	0.475
APZ42_001966	APZ42_020876	A0A164ILW2	A0A164X5L5	Class A rhodopsin G-protein-coupled receptor gprdop2.	Putative Class A rhodopsin G-protein-coupled receptor gprdop2.	0.482
APZ42_001966	APZ42_023975	A0A164ILW2	A0A164UB81	Class A rhodopsin G-protein-coupled receptor gprdop2.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.	0.543
APZ42_010947	APZ42_026543	A0A0P5PKK7	A0A164S5H9	5'-AMP-activated protein kinase subunit beta-1.	Peroxisome proliferator-activated receptor gamma coactivator-related-like protein.	0.713
APZ42_011645	APZ42_001966	A0A0P5TMV7	A0A164ILW2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	Class A rhodopsin G-protein-coupled receptor gprdop2.	0.516
APZ42_011645	APZ42_015097	A0A0P5TMV7	A0A0P5YZI9	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	Glucose-dependent insulinotropic receptor; Belongs to the G-protein coupled receptor 1 family.	0.446
APZ42_011645	APZ42_016259	A0A0P5TMV7	A0A165AIN5	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	Putative Class A rhodopsin G-protein-coupled receptor gprdop2.	0.516
APZ42_011645	APZ42_020876	A0A0P5TMV7	A0A164X5L5	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	Putative Class A rhodopsin G-protein-coupled receptor gprdop2.	0.516
APZ42_014229	APZ42_001519	A0A162Q5U9	A0A164IXF7	Long-chain-fatty-acid--CoA ligase.	Long-chain-fatty-acid--CoA ligase.	0.941
APZ42_014229	APZ42_015782	A0A162Q5U9	A0A0P6DJ83	Long-chain-fatty-acid--CoA ligase.	Long-chain-fatty-acid--CoA ligase bubblegum-like protein.	0.776
APZ42_014233	APZ42_015782	A0A0P5RQL3	A0A0P6DJ83	Long-chain-fatty-acid--CoA ligase 5.	Long-chain-fatty-acid--CoA ligase bubblegum-like protein.	0.778
APZ42_014234	APZ42_015782	A0A162Q5Z8	A0A0P6DJ83	Long-chain-fatty-acid--CoA ligase 5.	Long-chain-fatty-acid--CoA ligase bubblegum-like protein.	0.777
APZ42_015097	APZ42_001966	A0A0P5YZI9	A0A164ILW2	Glucose-dependent insulinotropic receptor; Belongs to the G-protein coupled receptor 1 family.	Class A rhodopsin G-protein-coupled receptor gprdop2.	0.835
APZ42_015097	APZ42_011645	A0A0P5YZI9	A0A0P5TMV7	Glucose-dependent insulinotropic receptor; Belongs to the G-protein coupled receptor 1 family.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.446
APZ42_015097	APZ42_016259	A0A0P5YZI9	A0A165AIN5	Glucose-dependent insulinotropic receptor; Belongs to the G-protein coupled receptor 1 family.	Putative Class A rhodopsin G-protein-coupled receptor gprdop2.	0.846
APZ42_015097	APZ42_020876	A0A0P5YZI9	A0A164X5L5	Glucose-dependent insulinotropic receptor; Belongs to the G-protein coupled receptor 1 family.	Putative Class A rhodopsin G-protein-coupled receptor gprdop2.	0.841