(47 nodes) Regulation of ERK1 and ERK2 cascade network (Daphnia magna)

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	APZ42_020123	Protein kinase domain-containing protein. (468 aa)
	APZ42_019333	Sprouty. (464 aa)
	APZ42_022330	Guanine nucleotide exchange factor VAV3. (805 aa)
	APZ42_023063	SH2B adapter protein 3. (577 aa)
	APZ42_024303	Putative Inactive tyrosine-protein kinase 7. (1141 aa)
	APZ42_025128	Dedicator of cytokinesis protein 5; Belongs to the DOCK family. (2017 aa)
	APZ42_025275	Putative Connector enhancer of kinase suppressor of ras 1. (1857 aa)
	APZ42_025382	Vav protein. (172 aa)
	APZ42_025689	Protein tyrosine phosphatase ERK-like protein. (650 aa)
	APZ42_025854	Uncharacterized protein. (884 aa)
	APZ42_026107	Raf serine/threonine-protein kinase phl. (913 aa)
	APZ42_029542	Mast/stem cell growth factor receptor Kit. (903 aa)
	APZ42_030789	Ras-related protein Rap-1B. (131 aa)
	APZ42_032195	Pro-neuregulin-2, membrane-bound-like protein. (466 aa)
	APZ42_000652	Uncharacterized protein. (215 aa)
	APZ42_021685	Tyrosine-protein kinase JAK1. (1217 aa)
	APZ42_001617	Purity of essence protein. (235 aa)
	APZ42_002734	Pro-neuregulin-2, membrane-bound. (63 aa)
	APZ42_008209	Purity of essence protein. (228 aa)
	APZ42_011711	Purity of essence protein. (4218 aa)
	APZ42_011221	cAMP-specific 3',5'-cyclic phosphodiesterase 7B; Belongs to the cyclic nucleotide phosphodiesterase family. (995 aa)
	APZ42_012300	Ubiquitin-conjugating enzyme E2-17 kDa; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
	APZ42_012425	Kinase suppressor of Ras 1. (978 aa)
	APZ42_014832	E3 ubiquitin-protein ligase HECTD1. (3106 aa)
	APZ42_024651	Putative Tyrosine-protein phosphatase non-receptor type 1. (512 aa)
	APZ42_011380	Ubiquitin carboxyl-terminal hydrolase 47; Belongs to the peptidase C19 family. (1402 aa)
	APZ42_025380	Guanine nucleotide exchange factor VAV2. (546 aa)
	APZ42_019958	Uncharacterized protein. (933 aa)
	APZ42_019024	Putative Dual specificity protein phosphatase Mpk3. (435 aa)
	APZ42_019921	Protein kinase domain-containing protein. (749 aa)
	APZ42_013520	Sptzle 1B. (218 aa)
	APZ42_032372	Receptor protein-tyrosine kinase. (1457 aa)
	APZ42_011043	Rho GTPase activating protein at 5A. (444 aa)
	APZ42_018666	Putative Cytohesin-1. (589 aa)
	APZ42_015040	Phosphoinositide phospholipase C. (1294 aa)
	APZ42_011343	Rho GTPase-activating protein 68F. (483 aa)
	APZ42_021706	Serine/threonine/tyrosine-interacting protein. (205 aa)
	APZ42_015618	Putative E3 ubiquitin-protein ligase CBL-B. (544 aa)
	APZ42_020054	Putative Vascular endothelial growth factor receptor 3. (1011 aa)
	APZ42_020116	Putative Receptor-type tyrosine-protein kinase FLT3. (791 aa)
	APZ42_020161	Putative Vascular endothelial growth factor receptor 1. (994 aa)
	APZ42_020156	Protein kinase domain-containing protein. (1515 aa)
	APZ42_020225	Receptor protein-tyrosine kinase. (1213 aa)
	APZ42_019443	Enhancer of sevenless 2B protein. (211 aa)
	APZ42_018320	Sprouty-related protein with EVH-1 domain. (599 aa)
	APZ42_018316	Tyrosine-protein kinase receptor. (1330 aa)
	APZ42_018131	Non-specific serine/threonine protein kinase. (649 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_000652	APZ42_013520	A0A164JH90	A0A0P6FSD2	Uncharacterized protein.	Sptzle 1B.	0.509
APZ42_000652	APZ42_015040	A0A164JH90	A0A0P5Y732	Uncharacterized protein.	Phosphoinositide phospholipase C.	0.653
APZ42_000652	APZ42_015618	A0A164JH90	A0A0P5CJL7	Uncharacterized protein.	Putative E3 ubiquitin-protein ligase CBL-B.	0.596
APZ42_000652	APZ42_018316	A0A164JH90	A0A164Z3T8	Uncharacterized protein.	Tyrosine-protein kinase receptor.	0.546
APZ42_000652	APZ42_019443	A0A164JH90	A0A164Y7E8	Uncharacterized protein.	Enhancer of sevenless 2B protein.	0.701
APZ42_000652	APZ42_030789	A0A164JH90	A0A164NC55	Uncharacterized protein.	Ras-related protein Rap-1B.	0.509
APZ42_001617	APZ42_011711	A0A164IV48	A0A162SYB9	Purity of essence protein.	Purity of essence protein.	0.459
APZ42_002734	APZ42_013520	A0A164I2R4	A0A0P6FSD2	Pro-neuregulin-2, membrane-bound.	Sptzle 1B.	0.522
APZ42_002734	APZ42_019443	A0A164I2R4	A0A164Y7E8	Pro-neuregulin-2, membrane-bound.	Enhancer of sevenless 2B protein.	0.627
APZ42_002734	APZ42_030789	A0A164I2R4	A0A164NC55	Pro-neuregulin-2, membrane-bound.	Ras-related protein Rap-1B.	0.522
APZ42_008209	APZ42_011711	A0A164ESY4	A0A162SYB9	Purity of essence protein.	Purity of essence protein.	0.841
APZ42_011043	APZ42_013520	A0A0P5ZI83	A0A0P6FSD2	Rho GTPase activating protein at 5A.	Sptzle 1B.	0.585
APZ42_011043	APZ42_015040	A0A0P5ZI83	A0A0P5Y732	Rho GTPase activating protein at 5A.	Phosphoinositide phospholipase C.	0.526
APZ42_011043	APZ42_015618	A0A0P5ZI83	A0A0P5CJL7	Rho GTPase activating protein at 5A.	Putative E3 ubiquitin-protein ligase CBL-B.	0.548
APZ42_011043	APZ42_019443	A0A0P5ZI83	A0A164Y7E8	Rho GTPase activating protein at 5A.	Enhancer of sevenless 2B protein.	0.541
APZ42_011043	APZ42_030789	A0A0P5ZI83	A0A164NC55	Rho GTPase activating protein at 5A.	Ras-related protein Rap-1B.	0.585
APZ42_011343	APZ42_013520	A0A0P5T3B5	A0A0P6FSD2	Rho GTPase-activating protein 68F.	Sptzle 1B.	0.549
APZ42_011343	APZ42_030789	A0A0P5T3B5	A0A164NC55	Rho GTPase-activating protein 68F.	Ras-related protein Rap-1B.	0.549
APZ42_011711	APZ42_001617	A0A162SYB9	A0A164IV48	Purity of essence protein.	Purity of essence protein.	0.459
APZ42_011711	APZ42_008209	A0A162SYB9	A0A164ESY4	Purity of essence protein.	Purity of essence protein.	0.841