(91 nodes) Secretory vesicle network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_032227	Septin-4; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (384 aa)
	APZ42_029568	Chromaffin granule amine transporter. (499 aa)
	APZ42_029214	Loss of heterozygosity 12 chromosomal region 1 protein. (252 aa)
	APZ42_026103	Septin-1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (368 aa)
	APZ42_019009	Plasma alpha-L-fucosidase; Belongs to the glycosyl hydrolase 29 family. (499 aa)
	APZ42_022061	Synaptotagmin-11. (517 aa)
	APZ42_017992	Secretory carrier-associated membrane protein. (346 aa)
	EOG090X04HR	Vesicular inhibitory amino acid transporter. (501 aa)
	APZ42_029903	Ras-related protein Rab-27A. (223 aa)
	EOG090X03QA	Vacuolar protein sorting-associated protein 45; Belongs to the STXBP/unc-18/SEC1 family. (578 aa)
	APZ42_022407	DOMON domain-containing protein. (188 aa)
	APZ42_016259	Putative Class A rhodopsin G-protein-coupled receptor gprdop2. (421 aa)
	APZ42_016314	DOMON domain-containing protein. (174 aa)
	APZ42_017116	BAI1-associated protein 3. (669 aa)
	APZ42_017331	Frequenin-1. (187 aa)
	APZ42_018039	MARVEL domain-containing protein. (230 aa)
	APZ42_017996	Secretory carrier-associated membrane protein. (323 aa)
	APZ42_019116	Phosphatidylinositol-binding clathrin assembly protein. (431 aa)
	APZ42_019499	Uncharacterized protein. (294 aa)
	APZ42_019901	Synaptotagmin 2 variant 2-like protein. (911 aa)
	APZ42_019864	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (174 aa)
	APZ42_020876	Putative Class A rhodopsin G-protein-coupled receptor gprdop2. (315 aa)
	APZ42_021214	Putative Multiple C2 and transmembrane domain-containing protein 1. (988 aa)
	APZ42_021256	Sec1 family domain-containing protein; Belongs to the STXBP/unc-18/SEC1 family. (474 aa)
	APZ42_022192	Putative Phorbol ester/diacylglycerol-binding protein unc-13. (1074 aa)
	APZ42_022183	Protein unc-13 A. (3026 aa)
	APZ42_022874	DBH monooxygenase 1-like protein. (636 aa)
	APZ42_022369	MAP kinase-activating death domain protein. (1753 aa)
	APZ42_022951	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (207 aa)
	APZ42_025198	Neuronal calcium sensor 2. (66 aa)
	APZ42_025712	Putative BAI1-associated protein 3. (712 aa)
	APZ42_026733	Synaptogyrin-3. (246 aa)
	APZ42_027004	RAB3GAP2_N domain-containing protein. (400 aa)
	APZ42_027103	PRKCA-binding protein. (441 aa)
	APZ42_027223	Putative Synaptic vesicular amine transporter. (158 aa)
	APZ42_028074	Calcium-dependent secretion activator 1. (1367 aa)
	APZ42_028837	RAB3GAP2_C domain-containing protein. (903 aa)
	APZ42_029896	Protein unc-13 D. (1262 aa)
	APZ42_030081	Cysteine string protein. (85 aa)
	APZ42_030823	DOMON domain-containing protein. (172 aa)
	EOG090X04X8	Vesicular glutamate transporter 2. (609 aa)
	APZ42_032582	FYVE-type domain-containing protein. (115 aa)
	APZ42_032544	Uncharacterized protein. (3708 aa)
	APZ42_032515	Synaptotagmin 1 protein, variant 2. (445 aa)
	APZ42_033023	Putative TGF-beta ligand glass bottom boat protein. (459 aa)
	APZ42_001854	Dihydrolipoamide dehydrogenase-like protein. (117 aa)
	APZ42_001966	Class A rhodopsin G-protein-coupled receptor gprdop2. (104 aa)
	APZ42_007372	Putative MAP kinase-activating death domain protein. (148 aa)
	APZ42_010960	Uncharacterized protein. (695 aa)
	APZ42_011075	Proton-associated sugar transporter A. (626 aa)
	APZ42_011307	Synaptotagmin-15. (464 aa)
	APZ42_011281	Zinc transporter ZIP13. (441 aa)
	APZ42_012149	Plasma alpha-L-fucosidase; Belongs to the glycosyl hydrolase 29 family. (467 aa)
	APZ42_012853	Putative Synaptotagmin 7. (659 aa)
	APZ42_012929	Vesicle-associated membrane protein 8. (122 aa)
	APZ42_013174	Ras-related protein Rab-10. (201 aa)
	APZ42_013485	Sec1 family domain-containing protein. (216 aa)
	APZ42_013700	Synaptotagmin-17. (549 aa)
	APZ42_013830	Putative Stonin-1. (1840 aa)
	APZ42_015385	Synapsin. (568 aa)
	APZ42_025179	Guanylyl cyclase-activating protein 2. (228 aa)
	APZ42_032784	Putative Synaptotagmin beta. (897 aa)
	APZ42_002221	Dihydrolipoamide dehydrogenase-like protein. (160 aa)
	APZ42_012229	Ras-related protein Rab-11A. (215 aa)
	APZ42_018558	Uncharacterized protein. (317 aa)
	APZ42_018911	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1663 aa)
	APZ42_018682	C2 domain-containing protein. (244 aa)
	APZ42_020216	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (228 aa)
	APZ42_020803	DBH monooxygenase 1-like protein. (799 aa)
	APZ42_021219	Rab proteins geranylgeranyltransferase component A. (494 aa)
	APZ42_026207	7,8-dihydro-8-oxoguanine triphosphatase. (157 aa)
	APZ42_022906	Inositol 1,4,5-trisphosphate receptor type. (2851 aa)
	APZ42_014248	Ras-related protein Rab-35. (201 aa)
	APZ42_023498	Putative Jelly Belly. (477 aa)
	APZ42_012144	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (621 aa)
	APZ42_014537	Vesicle-associated membrane protein 4. (135 aa)
	APZ42_030799	Xylose isomerase. (438 aa)
	APZ42_019868	Syntaxin-12; Belongs to the syntaxin family. (270 aa)
	APZ42_028251	GTP-binding protein 2. (605 aa)
	APZ42_028914	Putative Receptor-type tyrosine-protein phosphatase N2. (940 aa)
	APZ42_011460	Calcineurin subunit B type 2. (170 aa)
	APZ42_027289	Chloride channel protein. (802 aa)
	APZ42_015192	Chloride channel protein. (853 aa)
	APZ42_018524	60S ribosomal export protein NMD3. (541 aa)
	APZ42_023165	Syntaxin-binding protein; Belongs to the STXBP/unc-18/SEC1 family. (588 aa)
	APZ42_012420	Ras-related protein Rab-8A. (211 aa)
	APZ42_026719	Guanine nucleotide exchange factor for Rab-3A. (330 aa)
	APZ42_024157	IQ and ubiquitin domain-containing protein. (479 aa)
	APZ42_016928	Vesicle transport through interaction with t-SNAREsB. (227 aa)
	APZ42_024201	AP-1 complex subunit gamma. (912 aa)
	APZ42_014065	Syntaxin-6; Belongs to the syntaxin family. (258 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_001854	APZ42_002221	A0A164IPI5	A0A162CZ45	Dihydrolipoamide dehydrogenase-like protein.	Dihydrolipoamide dehydrogenase-like protein.	0.946
APZ42_001854	APZ42_024157	A0A164IPI5	A0A0P5M1L6	Dihydrolipoamide dehydrogenase-like protein.	IQ and ubiquitin domain-containing protein.	0.455
APZ42_001966	APZ42_016259	A0A164ILW2	A0A165AIN5	Class A rhodopsin G-protein-coupled receptor gprdop2.	Putative Class A rhodopsin G-protein-coupled receptor gprdop2.	0.475
APZ42_001966	APZ42_020876	A0A164ILW2	A0A164X5L5	Class A rhodopsin G-protein-coupled receptor gprdop2.	Putative Class A rhodopsin G-protein-coupled receptor gprdop2.	0.482
APZ42_002221	APZ42_001854	A0A162CZ45	A0A164IPI5	Dihydrolipoamide dehydrogenase-like protein.	Dihydrolipoamide dehydrogenase-like protein.	0.946
APZ42_002221	APZ42_024157	A0A162CZ45	A0A0P5M1L6	Dihydrolipoamide dehydrogenase-like protein.	IQ and ubiquitin domain-containing protein.	0.455
APZ42_007372	APZ42_014248	A0A164FBY1	A0A0P5ZIH4	Putative MAP kinase-activating death domain protein.	Ras-related protein Rab-35.	0.412
APZ42_007372	APZ42_029903	A0A164FBY1	A0A0N8E224	Putative MAP kinase-activating death domain protein.	Ras-related protein Rab-27A.	0.744
APZ42_010960	APZ42_012229	A0A162TCE3	A0A162CY40	Uncharacterized protein.	Ras-related protein Rab-11A.	0.713
APZ42_010960	APZ42_012420	A0A162TCE3	A0A0P5R8P7	Uncharacterized protein.	Ras-related protein Rab-8A.	0.615
APZ42_010960	APZ42_012929	A0A162TCE3	A0A162RBY0	Uncharacterized protein.	Vesicle-associated membrane protein 8.	0.521
APZ42_010960	APZ42_013174	A0A162TCE3	A0A162R329	Uncharacterized protein.	Ras-related protein Rab-10.	0.615
APZ42_010960	APZ42_014065	A0A162TCE3	A0A0P5K8X5	Uncharacterized protein.	Syntaxin-6; Belongs to the syntaxin family.	0.498
APZ42_010960	APZ42_014537	A0A162TCE3	A0A0P5WNA0	Uncharacterized protein.	Vesicle-associated membrane protein 4.	0.620
APZ42_010960	APZ42_018911	A0A162TCE3	A0A162CQ61	Uncharacterized protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.564
APZ42_010960	APZ42_019901	A0A162TCE3	A0A164XUP4	Uncharacterized protein.	Synaptotagmin 2 variant 2-like protein.	0.488
APZ42_010960	APZ42_020216	A0A162TCE3	A0A162CEI2	Uncharacterized protein.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.473
APZ42_010960	APZ42_022906	A0A162TCE3	A0A0P5ZUN0	Uncharacterized protein.	Inositol 1,4,5-trisphosphate receptor type.	0.518
APZ42_010960	APZ42_026103	A0A162TCE3	A0A0P5FMS9	Uncharacterized protein.	Septin-1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	0.577
APZ42_010960	APZ42_026719	A0A162TCE3	A0A0P5PU75	Uncharacterized protein.	Guanine nucleotide exchange factor for Rab-3A.	0.655