(68 nodes) Proton transmembrane transport network (Daphnia magna)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

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Your Input:
	APZ42_019435	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (479 aa)
	APZ42_003214	Putative Cytochrome b. (161 aa)
	APZ42_030256	Otopetrin-3. (902 aa)
	APZ42_030022	Uncharacterized protein. (494 aa)
	APZ42_028551	Sodium/hydrogen exchanger. (545 aa)
	APZ42_027189	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (694 aa)
	APZ42_025709	Uncharacterized protein. (1365 aa)
	APZ42_015083	Anion exchange protein. (1204 aa)
	APZ42_015150	Otopetrin-2. (813 aa)
	APZ42_015196	Otopetrin-2. (772 aa)
	APZ42_014595	Sodium/hydrogen exchanger; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (1011 aa)
	APZ42_014599	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (783 aa)
	APZ42_013832	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (1135 aa)
	APZ42_013834	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (903 aa)
	APZ42_013391	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (348 aa)
	APZ42_013260	Sodium/potassium-transporting ATPase subunit alpha; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1168 aa)
	APZ42_013266	Uncharacterized protein. (279 aa)
	APZ42_013264	Otopetrin-2. (422 aa)
	EOG090X0JDB	ATP synthase, delta subunit. (160 aa)
	APZ42_011644	Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (273 aa)
	APZ42_011075	Proton-associated sugar transporter A. (626 aa)
	APZ42_004276	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (128 aa)
	APZ42_003292	Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (80 aa)
	APZ42_001548	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (55 aa)
	APZ42_034432	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (836 aa)
	APZ42_033782	Glyco_trans_2-like domain-containing protein. (131 aa)
	APZ42_033391	V-type proton ATPase subunit B. (361 aa)
	APZ42_027374	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (84 aa)
	APZ42_034376	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family. (209 aa)
	APZ42_019657	Alkylated DNA repair protein alkB. (288 aa)
	APZ42_030709	LETM1 and EF-hand domain-containing protein 1, mitochondrial. (715 aa)
	APZ42_032076	Ion_trans domain-containing protein. (289 aa)
	APZ42_032065	Uncharacterized protein. (1097 aa)
	APZ42_032077	Uncharacterized protein. (393 aa)
	APZ42_030714	LETM1 and EF-hand domain-containing protein anon-60Da. (427 aa)
	APZ42_030246	ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (549 aa)
	APZ42_029455	Acetyl-Coenzyme A transporter 1. (495 aa)
	APZ42_029278	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (385 aa)
	APZ42_028323	NADH dehydrogenase iron-sulfur protein 7; Belongs to the complex I 20 kDa subunit family. (269 aa)
	APZ42_027708	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (160 aa)
	EOG090X0JXG	Putative ATP synthase subunit f, mitochondrial. (108 aa)
	APZ42_016306	LETM1 domain-containing protein 1. (351 aa)
	APZ42_025226	Mt:coi. (48 aa)
	APZ42_025225	Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (123 aa)
	APZ42_022451	Sodium/potassium-transporting ATPase subunit alpha. (856 aa)
	APZ42_022611	Sodium/potassium-transporting ATPase subunit alpha; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1058 aa)
	APZ42_022631	Putative Sodium/potassium-transporting ATPase subunit alpha; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (603 aa)
	APZ42_020909	NAD(P) transhydrogenase, mitochondrial. (1064 aa)
	APZ42_019720	ATP synthase subunit epsilon. (58 aa)
	APZ42_020153	V-type proton ATPase subunit D 1. (202 aa)
	APZ42_020164	V-type proton ATPase subunit D. (244 aa)
	APZ42_020220	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (122 aa)
	APZ42_018744	ATP synthase subunit e, mitochondrial. (84 aa)
	APZ42_017129	Sodium bicarbonate transporter protein 11. (864 aa)
	EOG090X0F8Y	V-type proton ATPase subunit E 1. (226 aa)
	APZ42_015075	Anion exchange protein. (1071 aa)
	APZ42_027183	Cytochrome c1, heme protein, mitochondrial. (306 aa)
	APZ42_017384	Sodium/potassium-transporting ATPase subunit alpha. (675 aa)
	APZ42_016944	Renin receptor. (308 aa)
	APZ42_029275	V-type proton ATPase catalytic subunit A. (621 aa)
	EOG090X04HR	Vesicular inhibitory amino acid transporter. (501 aa)
	APZ42_024778	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (117 aa)
	APZ42_022518	Sodium/hydrogen exchanger. (589 aa)
	APZ42_019811	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (699 aa)
	APZ42_019517	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (499 aa)
	APZ42_007003	Sodium/potassium-transporting ATPase subunit alpha. (232 aa)
	APZ42_017392	Sodium/potassium-transporting ATPase subunit alpha; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (239 aa)
	APZ42_020006	Sodium bicarbonate transporter 11-like protein. (810 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_001548	APZ42_007003	A0A164IWM1	A0A162BV61	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Sodium/potassium-transporting ATPase subunit alpha.	0.574
APZ42_001548	APZ42_013260	A0A164IWM1	A0A162R568	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Sodium/potassium-transporting ATPase subunit alpha; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.574
APZ42_001548	APZ42_013391	A0A164IWM1	A0A162QZL3	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	0.996
APZ42_001548	APZ42_016944	A0A164IWM1	A0A165A9N8	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Renin receptor.	0.879
APZ42_001548	APZ42_017384	A0A164IWM1	A0A164ZV32	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Sodium/potassium-transporting ATPase subunit alpha.	0.574
APZ42_001548	APZ42_017392	A0A164IWM1	A0A162CK86	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Sodium/potassium-transporting ATPase subunit alpha; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.574
APZ42_001548	APZ42_019435	A0A164IWM1	A0A162CNC8	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	0.983
APZ42_001548	APZ42_019517	A0A164IWM1	A0A0P6IW21	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.959
APZ42_001548	APZ42_019657	A0A164IWM1	A0A0P5ZDB6	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Alkylated DNA repair protein alkB.	0.895
APZ42_001548	APZ42_020153	A0A164IWM1	A0A164Y1P1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit D 1.	0.895
APZ42_001548	APZ42_020164	A0A164IWM1	A0A164Y1Q7	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit D.	0.895
APZ42_001548	APZ42_020220	A0A164IWM1	A0A164Y3M2	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.989
APZ42_001548	APZ42_022451	A0A164IWM1	A0A164VIW5	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Sodium/potassium-transporting ATPase subunit alpha.	0.574
APZ42_001548	APZ42_022611	A0A164IWM1	A0A164VN38	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Sodium/potassium-transporting ATPase subunit alpha; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.574
APZ42_001548	APZ42_022631	A0A164IWM1	A0A164VNA3	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Putative Sodium/potassium-transporting ATPase subunit alpha; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.574
APZ42_001548	APZ42_024778	A0A164IWM1	A0A0N8D104	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.972
APZ42_001548	APZ42_027374	A0A164IWM1	A0A0P6AZU9	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.970
APZ42_001548	APZ42_027708	A0A164IWM1	A0A164R4R3	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.995
APZ42_001548	APZ42_029275	A0A164IWM1	A0A0P5EA36	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase catalytic subunit A.	0.995
APZ42_001548	APZ42_029278	A0A164IWM1	A0A164PT35	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.974