(39 nodes) Histone deacetylase complex network (Daphnia magna)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	APZ42_022286	Actin-related protein; Belongs to the actin family. (394 aa)
	APZ42_002198	Craniofacial development protein 1. (234 aa)
	EOG090X0IS7	Breast cancer metastasis-suppressor 1 protein-A. (260 aa)
	APZ42_012709	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (540 aa)
	APZ42_017650	Histone-binding protein RBBP4. (428 aa)
	APZ42_028242	Putative Metastasis-associated protein MTA1. (872 aa)
	EOG090X0GXS	Putative Zinc finger HIT domain-containing protein. (156 aa)
	EOG090X0BDJ	Methyl-CpG-binding domain protein 3. (249 aa)
	APZ42_021069	Hdac6. (57 aa)
	APZ42_020467	Protein FAM60A. (265 aa)
	APZ42_026807	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (434 aa)
	APZ42_019264	Mortality factor 4 1-like protein. (356 aa)
	APZ42_024060	Sin3 Histone deacetylase corepressor complex component SDS3. (388 aa)
	APZ42_020282	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1140 aa)
	APZ42_015226	Bromodomain-containing protein. (849 aa)
	APZ42_020180	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (392 aa)
	APZ42_022907	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. (438 aa)
	APZ42_028349	REST corepressor 3. (474 aa)
	EOG090X076S	DNA methyltransferase 1-associated protein. (479 aa)
	APZ42_016293	Lysine-specific demethylase lid. (1579 aa)
	APZ42_018393	AT-rich interactive domain-containing 4B-like protein. (1711 aa)
	APZ42_018671	PHD finger protein 12. (766 aa)
	APZ42_019918	ENT domain-containing protein. (625 aa)
	APZ42_021349	Paired amphipathic helix protein Sin3b. (1315 aa)
	APZ42_024657	SAP130_C domain-containing protein. (176 aa)
	APZ42_025183	Integrase_H2C2 domain-containing protein. (1504 aa)
	APZ42_026195	Putative Transcriptional repressor p66-beta. (960 aa)
	APZ42_028561	Putative Histone deacetylase HDAC6 protein. (1041 aa)
	APZ42_030032	Putative Hdac6. (446 aa)
	APZ42_030955	Uncharacterized protein. (1451 aa)
	APZ42_031872	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. (433 aa)
	APZ42_034207	Integrase_H2C2 domain-containing protein. (186 aa)
	APZ42_003891	Integrase_H2C2 domain-containing protein. (109 aa)
	APZ42_007265	Integrase catalytic domain-containing protein. (183 aa)
	APZ42_009376	Integrase_H2C2 domain-containing protein. (99 aa)
	APZ42_009597	Integrase_H2C2 domain-containing protein. (191 aa)
	APZ42_011793	Uncharacterized protein. (2828 aa)
	APZ42_014559	Histone deacetylase 6-like protein. (313 aa)
	APZ42_015253	JmjC domain-containing histone demethylase 2. (2420 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_002198	APZ42_022286	A0A162C5Q9	A0A0N8D2A5	Craniofacial development protein 1.	Actin-related protein; Belongs to the actin family.	0.735
APZ42_002198	APZ42_022907	A0A162C5Q9	A0A162C8G0	Craniofacial development protein 1.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.	0.966
APZ42_002198	APZ42_031872	A0A162C5Q9	A0A164MDA0	Craniofacial development protein 1.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.	0.936
APZ42_002198	EOG090X076S	A0A162C5Q9	A0A0N7ZTW8	Craniofacial development protein 1.	DNA methyltransferase 1-associated protein.	0.966
APZ42_002198	EOG090X0GXS	A0A162C5Q9	A0A0P5T8V4	Craniofacial development protein 1.	Putative Zinc finger HIT domain-containing protein.	0.860
APZ42_003891	APZ42_011793	A0A164HDE4	A0A162T115	Integrase_H2C2 domain-containing protein.	Uncharacterized protein.	0.501
APZ42_003891	APZ42_012709	A0A164HDE4	A0A0P5V584	Integrase_H2C2 domain-containing protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.790
APZ42_003891	APZ42_014559	A0A164HDE4	A0A162PQP9	Integrase_H2C2 domain-containing protein.	Histone deacetylase 6-like protein.	0.668
APZ42_003891	APZ42_017650	A0A164HDE4	A0A0P5V197	Integrase_H2C2 domain-containing protein.	Histone-binding protein RBBP4.	0.915
APZ42_003891	APZ42_019264	A0A164HDE4	A0A0P5ETC0	Integrase_H2C2 domain-containing protein.	Mortality factor 4 1-like protein.	0.479
APZ42_003891	APZ42_020180	A0A164HDE4	A0A0P4XN91	Integrase_H2C2 domain-containing protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.790
APZ42_003891	APZ42_020282	A0A164HDE4	A0A0P5BZJ2	Integrase_H2C2 domain-containing protein.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.668
APZ42_003891	APZ42_021069	A0A164HDE4	A0A0P5J723	Integrase_H2C2 domain-containing protein.	Hdac6.	0.668
APZ42_003891	APZ42_026807	A0A164HDE4	A0A0P5EVU3	Integrase_H2C2 domain-containing protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.790
APZ42_003891	APZ42_028242	A0A164HDE4	A0A0P5UUK1	Integrase_H2C2 domain-containing protein.	Putative Metastasis-associated protein MTA1.	0.790
APZ42_003891	APZ42_028561	A0A164HDE4	A0A164Q769	Integrase_H2C2 domain-containing protein.	Putative Histone deacetylase HDAC6 protein.	0.668
APZ42_003891	APZ42_030032	A0A164HDE4	A0A164P459	Integrase_H2C2 domain-containing protein.	Putative Hdac6.	0.668
APZ42_003891	EOG090X0BDJ	A0A164HDE4	A0A0P5JSE9	Integrase_H2C2 domain-containing protein.	Methyl-CpG-binding domain protein 3.	0.680
APZ42_007265	APZ42_011793	A0A164FE72	A0A162T115	Integrase catalytic domain-containing protein.	Uncharacterized protein.	0.501
APZ42_007265	APZ42_012709	A0A164FE72	A0A0P5V584	Integrase catalytic domain-containing protein.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.790