(16 nodes) Clathrin-coated pit network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_023544	Vesicular acetylcholine transporter-A. (637 aa)
	APZ42_017917	Epidermal growth factor receptor substrate 15 1-like protein. (1834 aa)
	APZ42_015608	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (943 aa)
	APZ42_026055	RalBP1-associated Eps domain-containing protein. (592 aa)
	APZ42_034126	Very Low-density lipoprotein receptor. (887 aa)
	APZ42_019116	Phosphatidylinositol-binding clathrin assembly protein. (431 aa)
	APZ42_021443	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (415 aa)
	APZ42_024105	Low-density lipoprotein receptor-related protein 2. (4941 aa)
	APZ42_021745	Protein TBRG4. (602 aa)
	APZ42_028067	FCH domain only protein 2. (995 aa)
	APZ42_028941	Low-density lipoprotein receptor-related protein 2. (4788 aa)
	APZ42_001817	Low-density lipoprotein receptor-related protein 2. (214 aa)
	APZ42_013654	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (145 aa)
	APZ42_016099	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
	APZ42_020788	AP complex subunit beta. (927 aa)
	APZ42_015545	Dynamin-1 protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (737 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_001817	APZ42_016099	A0A164IQA7	A0A162NMK5	Low-density lipoprotein receptor-related protein 2.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.559
APZ42_001817	APZ42_017917	A0A164IQA7	A0A0P5T7E4	Low-density lipoprotein receptor-related protein 2.	Epidermal growth factor receptor substrate 15 1-like protein.	0.619
APZ42_001817	APZ42_021443	A0A164IQA7	A0A164WPI1	Low-density lipoprotein receptor-related protein 2.	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.571
APZ42_001817	APZ42_024105	A0A164IQA7	A0A164UH83	Low-density lipoprotein receptor-related protein 2.	Low-density lipoprotein receptor-related protein 2.	0.903
APZ42_013654	APZ42_015545	A0A162QPP9	A0A0P6B973	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Dynamin-1 protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.589
APZ42_013654	APZ42_015608	A0A162QPP9	A0A0P5KQ01	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.933
APZ42_013654	APZ42_016099	A0A162QPP9	A0A162NMK5	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.415
APZ42_013654	APZ42_020788	A0A162QPP9	A0A0P6DXK2	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP complex subunit beta.	0.989
APZ42_013654	APZ42_021443	A0A162QPP9	A0A164WPI1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.617
APZ42_015545	APZ42_013654	A0A0P6B973	A0A162QPP9	Dynamin-1 protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.589
APZ42_015545	APZ42_015608	A0A0P6B973	A0A0P5KQ01	Dynamin-1 protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.769
APZ42_015545	APZ42_016099	A0A0P6B973	A0A162NMK5	Dynamin-1 protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.667
APZ42_015545	APZ42_017917	A0A0P6B973	A0A0P5T7E4	Dynamin-1 protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Epidermal growth factor receptor substrate 15 1-like protein.	0.975
APZ42_015545	APZ42_019116	A0A0P6B973	A0A164YKC7	Dynamin-1 protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Phosphatidylinositol-binding clathrin assembly protein.	0.653
APZ42_015545	APZ42_020788	A0A0P6B973	A0A0P6DXK2	Dynamin-1 protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	AP complex subunit beta.	0.849
APZ42_015545	APZ42_021443	A0A0P6B973	A0A164WPI1	Dynamin-1 protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.752
APZ42_015545	APZ42_021745	A0A0P6B973	A0A164WHT6	Dynamin-1 protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Protein TBRG4.	0.589
APZ42_015545	APZ42_028067	A0A0P6B973	A0A164QUI1	Dynamin-1 protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	FCH domain only protein 2.	0.421
APZ42_015608	APZ42_013654	A0A0P5KQ01	A0A162QPP9	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.933
APZ42_015608	APZ42_015545	A0A0P5KQ01	A0A0P6B973	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Dynamin-1 protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.769