(36 nodes) Coated vesicle membrane network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_033467	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (891 aa)
	APZ42_015608	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (943 aa)
	APZ42_024201	AP-1 complex subunit gamma. (912 aa)
	APZ42_017873	F-box/WD repeat-containing protein 1A. (775 aa)
	APZ42_023544	Vesicular acetylcholine transporter-A. (637 aa)
	APZ42_015724	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1060 aa)
	APZ42_019396	Transport protein Sec31A. (1244 aa)
	APZ42_028742	General vesicular transport factor p115. (894 aa)
	APZ42_015039	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (964 aa)
	APZ42_014592	Telomere length regulation protein TEL2. (1387 aa)
	APZ42_013796	Uncharacterized protein. (1206 aa)
	APZ42_013695	SREBP cleavage activating protein. (1312 aa)
	APZ42_012422	Putative Niemann-Pick C1 protein. (437 aa)
	APZ42_011609	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (515 aa)
	APZ42_002399	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (349 aa)
	APZ42_033286	Protein transport protein Sec24C. (1058 aa)
	APZ42_033197	NADH-cytochrome b5 reductase 1. (292 aa)
	APZ42_031428	Programmed cell death protein 6. (184 aa)
	EOG090X01FO	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (954 aa)
	APZ42_028262	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (95 aa)
	APZ42_027008	Epsin-1. (598 aa)
	APZ42_025210	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (141 aa)
	APZ42_023767	Deleted in autism protein 1. (497 aa)
	APZ42_023261	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family. (192 aa)
	APZ42_021533	Transport protein Sec24B protein. (210 aa)
	APZ42_021392	NECAP-like protein. (276 aa)
	APZ42_016099	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
	APZ42_019750	Transport Sec24B,-like protein. (400 aa)
	APZ42_017107	F-box/WD repeat-containing protein 1A. (523 aa)
	APZ42_020216	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (228 aa)
	APZ42_023120	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1224 aa)
	APZ42_020788	AP complex subunit beta. (927 aa)
	APZ42_021778	Patched domain-containing. (983 aa)
	EOG090X0A8E	Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family. (300 aa)
	APZ42_030563	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (803 aa)
	APZ42_029114	Vesicle transport through interaction with t-SNAREsA. (218 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_002399	APZ42_014592	A0A164IAD9	A0A162PRB3	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	Telomere length regulation protein TEL2.	0.431
APZ42_002399	APZ42_015608	A0A164IAD9	A0A0P5KQ01	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.925
APZ42_002399	APZ42_015724	A0A164IAD9	A0A162NQ33	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.833
APZ42_002399	APZ42_016099	A0A164IAD9	A0A162NMK5	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.659
APZ42_002399	APZ42_020216	A0A164IAD9	A0A162CEI2	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.873
APZ42_002399	APZ42_020788	A0A164IAD9	A0A0P6DXK2	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP complex subunit beta.	0.995
APZ42_002399	APZ42_021392	A0A164IAD9	A0A164WP81	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	NECAP-like protein.	0.665
APZ42_002399	APZ42_024201	A0A164IAD9	A0A0P5LLS2	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-1 complex subunit gamma.	0.996
APZ42_002399	APZ42_028262	A0A164IAD9	A0A164QM97	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	AP-1 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.485
APZ42_011609	APZ42_015039	A0A162SUV1	A0A162P536	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.999
APZ42_011609	APZ42_019396	A0A162SUV1	A0A0P5ZWL8	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	Transport protein Sec31A.	0.633
APZ42_011609	APZ42_020788	A0A162SUV1	A0A0P6DXK2	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	AP complex subunit beta.	0.598
APZ42_011609	APZ42_023120	A0A162SUV1	A0A0P6F5Z0	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.	0.998
APZ42_011609	APZ42_024201	A0A162SUV1	A0A0P5LLS2	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	AP-1 complex subunit gamma.	0.434
APZ42_011609	APZ42_025210	A0A162SUV1	A0A164TCA9	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	0.999
APZ42_011609	APZ42_028742	A0A162SUV1	A0A0P5YTG8	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	General vesicular transport factor p115.	0.760
APZ42_011609	APZ42_030563	A0A162SUV1	A0A0P5E3T1	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.639
APZ42_011609	APZ42_033467	A0A162SUV1	A0A0P6AG54	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.999
APZ42_011609	EOG090X01FO	A0A162SUV1	A0A164NM58	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.998
APZ42_011609	EOG090X0A8E	A0A162SUV1	A0A0P4X703	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family.	0.994