(9 nodes) Retromer complex network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_008838	Putative Sorting nexin-6. (85 aa)
	EOG090X05H4	Vacuolar protein sorting-associated protein 26. (370 aa)
	APZ42_021180	Down Syndrome critical region protein 3 protein. (234 aa)
	APZ42_022618	Sorting nexin; Involved in several stages of intracellular trafficking. (408 aa)
	EOG090X0GN3	Sorting nexin-12. (161 aa)
	APZ42_017011	Sorting nexin-2. (527 aa)
	EOG090X00QE	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (811 aa)
	APZ42_009082	Down Syndrome critical region protein 3 protein. (49 aa)
	APZ42_025807	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (183 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_008838	APZ42_017011	A0A164EDW6	A0A0P5ME33	Putative Sorting nexin-6.	Sorting nexin-2.	0.978
APZ42_008838	APZ42_025807	A0A164EDW6	A0A162EEN0	Putative Sorting nexin-6.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.586
APZ42_008838	EOG090X00QE	A0A164EDW6	A0A0P5P8Q8	Putative Sorting nexin-6.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.601
APZ42_008838	EOG090X05H4	A0A164EDW6	A0A164UXL5	Putative Sorting nexin-6.	Vacuolar protein sorting-associated protein 26.	0.583
APZ42_008838	EOG090X0GN3	A0A164EDW6	A0A0P5FHN5	Putative Sorting nexin-6.	Sorting nexin-12.	0.564
APZ42_009082	APZ42_025807	A0A162BRE4	A0A162EEN0	Down Syndrome critical region protein 3 protein.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.801
APZ42_009082	EOG090X00QE	A0A162BRE4	A0A0P5P8Q8	Down Syndrome critical region protein 3 protein.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.421
APZ42_017011	APZ42_008838	A0A0P5ME33	A0A164EDW6	Sorting nexin-2.	Putative Sorting nexin-6.	0.978
APZ42_017011	APZ42_022618	A0A0P5ME33	A0A164VN48	Sorting nexin-2.	Sorting nexin; Involved in several stages of intracellular trafficking.	0.978
APZ42_017011	APZ42_025807	A0A0P5ME33	A0A162EEN0	Sorting nexin-2.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.989
APZ42_017011	EOG090X00QE	A0A0P5ME33	A0A0P5P8Q8	Sorting nexin-2.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.990
APZ42_017011	EOG090X05H4	A0A0P5ME33	A0A164UXL5	Sorting nexin-2.	Vacuolar protein sorting-associated protein 26.	0.984
APZ42_017011	EOG090X0GN3	A0A0P5ME33	A0A0P5FHN5	Sorting nexin-2.	Sorting nexin-12.	0.656
APZ42_021180	APZ42_025807	A0A164X1T0	A0A162EEN0	Down Syndrome critical region protein 3 protein.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.801
APZ42_021180	EOG090X00QE	A0A164X1T0	A0A0P5P8Q8	Down Syndrome critical region protein 3 protein.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.421
APZ42_022618	APZ42_017011	A0A164VN48	A0A0P5ME33	Sorting nexin; Involved in several stages of intracellular trafficking.	Sorting nexin-2.	0.978
APZ42_022618	APZ42_025807	A0A164VN48	A0A162EEN0	Sorting nexin; Involved in several stages of intracellular trafficking.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.586
APZ42_022618	EOG090X00QE	A0A164VN48	A0A0P5P8Q8	Sorting nexin; Involved in several stages of intracellular trafficking.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.601
APZ42_022618	EOG090X05H4	A0A164VN48	A0A164UXL5	Sorting nexin; Involved in several stages of intracellular trafficking.	Vacuolar protein sorting-associated protein 26.	0.583
APZ42_022618	EOG090X0GN3	A0A164VN48	A0A0P5FHN5	Sorting nexin; Involved in several stages of intracellular trafficking.	Sorting nexin-12.	0.564