(68 nodes) SH3 domain network (Daphnia magna)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_019812	ArfGAP with SH3 domain, ankyrin repeat and PH domain. (1103 aa)
	APZ42_019230	Putative Guanine nucleotide exchange factor DBS. (1637 aa)
	APZ42_010847	Endophilin-A. (389 aa)
	APZ42_032511	Syndapin. (495 aa)
	APZ42_027298	Osteoclast-stimulating factor. (214 aa)
	APZ42_016105	Tyrosine-protein kinase. (515 aa)
	APZ42_015074	Microtubule-actin cross-linking factor 1. (5007 aa)
	APZ42_011222	Uncharacterized protein. (1085 aa)
	APZ42_004793	Uncharacterized protein. (299 aa)
	APZ42_002499	Putative Rho/Cdc42/Rac GTPase-activating protein RICS. (106 aa)
	APZ42_034304	Breast cancer anti-estrogen resistance protein 1. (868 aa)
	EOG090X03KK	Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. (584 aa)
	APZ42_032701	Uncharacterized protein. (966 aa)
	APZ42_031213	SH3 domain-containing protein. (417 aa)
	APZ42_029510	Putative SH3 and cysteine-rich domain-containing protein. (1282 aa)
	APZ42_029208	Signal transducing adapter molecule 1. (481 aa)
	APZ42_027807	SH3 domain-containing protein. (181 aa)
	APZ42_027627	Uncharacterized protein. (10574 aa)
	APZ42_027474	Voltage-dependent L-type calcium channel subunit beta-2. (850 aa)
	APZ42_027032	Putative LIM and SH3 domain protein Lasp. (461 aa)
	APZ42_026765	MAGUK p55 subfamily member 6; Belongs to the MAGUK family. (1302 aa)
	APZ42_026816	Peripheral plasma membrane protein CASK. (318 aa)
	APZ42_025631	Putative Amphiphysin. (139 aa)
	APZ42_025382	Vav protein. (172 aa)
	APZ42_025128	Dedicator of cytokinesis protein 5; Belongs to the DOCK family. (2017 aa)
	APZ42_024498	Spermatogenesis-associated 13-like protein. (1403 aa)
	APZ42_023814	SH3 domain-containing protein. (113 aa)
	APZ42_023495	Putative SH3 domain-containing kinase-binding protein. (650 aa)
	APZ42_022323	Myosin 10A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (3016 aa)
	APZ42_021640	Ubiquitin-associated and SH3 domain-containing protein B. (680 aa)
	APZ42_019725	Putative Sorbin and SH3 domain-containing protein. (969 aa)
	APZ42_019823	Putative Peripheral-type benzodiazepine receptor-associated protein. (681 aa)
	APZ42_019443	Enhancer of sevenless 2B protein. (211 aa)
	APZ42_019490	MAGUK p55 subfamily member 6; Belongs to the MAGUK family. (1368 aa)
	APZ42_019574	Uncharacterized protein. (704 aa)
	APZ42_019316	Tyrosine-protein kinase PR2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1215 aa)
	APZ42_017724	Putative cTAGE family member 5. (1716 aa)
	APZ42_016707	Dynamin-binding protein. (1362 aa)
	APZ42_010901	Abl interactor. (458 aa)
	APZ42_030077	Epidermal growth factor receptor kinase substrate 8 2-like protein. (829 aa)
	APZ42_034171	Cdc42-interacting protein 4. (632 aa)
	APZ42_023748	Tyrosine-protein kinase. (537 aa)
	APZ42_022004	Putative Tyrosine-protein kinase Btk29A. (1513 aa)
	APZ42_025752	SH3 and multiple ankyrin repeat domains protein. (1688 aa)
	APZ42_019019	Cytoplasmic protein NCK1. (474 aa)
	APZ42_020981	Disks large 1 tumor suppressor protein; Belongs to the MAGUK family. (912 aa)
	APZ42_033256	Putative Rho guanine nucleotide exchange factor 7. (611 aa)
	APZ42_012238	Lethal (3). (400 aa)
	APZ42_012106	C-Jun-amino-terminal kinase-interacting protein. (430 aa)
	APZ42_033988	Cytoplasmic protein NCK2. (407 aa)
	APZ42_011419	Peroxisomal membrane protein PEX13. (361 aa)
	APZ42_033186	Endophilin-B1. (335 aa)
	APZ42_011760	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide. (952 aa)
	APZ42_027285	Unconventional myosin-X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2172 aa)
	APZ42_017917	Epidermal growth factor receptor substrate 15 1-like protein. (1834 aa)
	APZ42_032066	FCH and double SH3 domains protein. (981 aa)
	APZ42_025681	Tyrosine-protein kinase. (712 aa)
	APZ42_015040	Phosphoinositide phospholipase C. (1294 aa)
	APZ42_020417	Kinase c and casein kinase substrate in neurons protein. (534 aa)
	APZ42_022107	Putative SH3 domain-containing RING finger protein 3. (805 aa)
	APZ42_031339	Spectrin alpha chain, non-erythrocytic. (2414 aa)
	APZ42_020867	Sorting nexin; Belongs to the sorting nexin family. (540 aa)
	APZ42_022452	Src substrate cortactin. (533 aa)
	APZ42_016095	Tyrosine-protein kinase. (524 aa)
	APZ42_022280	Putative Small G protein signaling modulator 3. (1368 aa)
	APZ42_020914	Spectrin beta chain. (3333 aa)
	APZ42_019695	Uncharacterized protein. (769 aa)
	APZ42_019810	Peripheral-type benzodiazepine receptor-associated 1-like protein. (1631 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_002499	APZ42_015040	A0A164I835	A0A0P5Y732	Putative Rho/Cdc42/Rac GTPase-activating protein RICS.	Phosphoinositide phospholipase C.	0.557
APZ42_002499	APZ42_017917	A0A164I835	A0A0P5T7E4	Putative Rho/Cdc42/Rac GTPase-activating protein RICS.	Epidermal growth factor receptor substrate 15 1-like protein.	0.740
APZ42_002499	APZ42_019019	A0A164I835	A0A0P4XJV0	Putative Rho/Cdc42/Rac GTPase-activating protein RICS.	Cytoplasmic protein NCK1.	0.457
APZ42_002499	APZ42_019443	A0A164I835	A0A164Y7E8	Putative Rho/Cdc42/Rac GTPase-activating protein RICS.	Enhancer of sevenless 2B protein.	0.484
APZ42_002499	APZ42_022107	A0A164I835	A0A0P5YEQ6	Putative Rho/Cdc42/Rac GTPase-activating protein RICS.	Putative SH3 domain-containing RING finger protein 3.	0.563
APZ42_002499	APZ42_034171	A0A164I835	A0A0N8D5K7	Putative Rho/Cdc42/Rac GTPase-activating protein RICS.	Cdc42-interacting protein 4.	0.439
APZ42_004793	APZ42_010847	A0A164GUB4	A0A162D0G8	Uncharacterized protein.	Endophilin-A.	0.581
APZ42_004793	APZ42_011760	A0A164GUB4	A0A0P5KQF9	Uncharacterized protein.	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide.	0.430
APZ42_004793	APZ42_012106	A0A164GUB4	A0A0P5D8G0	Uncharacterized protein.	C-Jun-amino-terminal kinase-interacting protein.	0.721
APZ42_004793	APZ42_015040	A0A164GUB4	A0A0P5Y732	Uncharacterized protein.	Phosphoinositide phospholipase C.	0.663
APZ42_004793	APZ42_015074	A0A164GUB4	A0A162P6X1	Uncharacterized protein.	Microtubule-actin cross-linking factor 1.	0.501
APZ42_004793	APZ42_016095	A0A164GUB4	A0A0P6H5F8	Uncharacterized protein.	Tyrosine-protein kinase.	0.631
APZ42_004793	APZ42_016105	A0A164GUB4	A0A162NLR5	Uncharacterized protein.	Tyrosine-protein kinase.	0.631
APZ42_004793	APZ42_017917	A0A164GUB4	A0A0P5T7E4	Uncharacterized protein.	Epidermal growth factor receptor substrate 15 1-like protein.	0.525
APZ42_004793	APZ42_019019	A0A164GUB4	A0A0P4XJV0	Uncharacterized protein.	Cytoplasmic protein NCK1.	0.599
APZ42_004793	APZ42_019443	A0A164GUB4	A0A164Y7E8	Uncharacterized protein.	Enhancer of sevenless 2B protein.	0.644
APZ42_004793	APZ42_019574	A0A164GUB4	A0A164YA42	Uncharacterized protein.	Uncharacterized protein.	0.578
APZ42_004793	APZ42_020981	A0A164GUB4	A0A0P4ZGY7	Uncharacterized protein.	Disks large 1 tumor suppressor protein; Belongs to the MAGUK family.	0.689
APZ42_004793	APZ42_021640	A0A164GUB4	A0A164WED7	Uncharacterized protein.	Ubiquitin-associated and SH3 domain-containing protein B.	0.438
APZ42_004793	APZ42_022107	A0A164GUB4	A0A0P5YEQ6	Uncharacterized protein.	Putative SH3 domain-containing RING finger protein 3.	0.539