(36 nodes) SH2 domain superfamily network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_011760	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide. (952 aa)
	APZ42_022197	Putative Cytokine-inducible SH2-containing protein. (528 aa)
	APZ42_025681	Tyrosine-protein kinase. (712 aa)
	APZ42_015040	Phosphoinositide phospholipase C. (1294 aa)
	APZ42_011043	Rho GTPase activating protein at 5A. (444 aa)
	APZ42_016954	SH2 domain-containing protein. (372 aa)
	APZ42_017454	Cytokine-inducible SH2-containing protein. (483 aa)
	APZ42_024029	Phosphatidylinositol 3-kinase regulatory subunit gamma. (409 aa)
	APZ42_023798	Pi3K21B. (782 aa)
	APZ42_025382	Vav protein. (172 aa)
	APZ42_027469	Putative Blistery. (645 aa)
	APZ42_018752	SH2 domain-containing protein. (530 aa)
	APZ42_019319	SHC-transforming protein 3. (1189 aa)
	APZ42_019443	Enhancer of sevenless 2B protein. (211 aa)
	APZ42_020171	Phosphoinositide phospholipase C. (748 aa)
	APZ42_020585	Uncharacterized protein. (79 aa)
	APZ42_020568	Tyrosine-protein kinase. (587 aa)
	APZ42_022330	Guanine nucleotide exchange factor VAV3. (805 aa)
	APZ42_023063	SH2B adapter protein 3. (577 aa)
	APZ42_028748	SH2 domain-containing protein. (939 aa)
	APZ42_030527	Uncharacterized protein. (399 aa)
	APZ42_031732	Tyrosine-protein kinase. (733 aa)
	APZ42_001425	Signal transducer and activator of transcription. (305 aa)
	APZ42_011282	Putative SH2 domain-containing protein 3C. (794 aa)
	APZ42_011191	Putative Tyrosine-protein kinase Fps85D. (917 aa)
	APZ42_012032	Putative Transcription elongation factor SPT6. (2295 aa)
	APZ42_016105	Tyrosine-protein kinase. (515 aa)
	APZ42_016993	Tyrosine-protein kinase. (393 aa)
	APZ42_014452	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (645 aa)
	APZ42_017933	Cytokine-inducible SH2-containing protein. (465 aa)
	APZ42_023748	Tyrosine-protein kinase. (537 aa)
	APZ42_022004	Putative Tyrosine-protein kinase Btk29A. (1513 aa)
	APZ42_019019	Cytoplasmic protein NCK1. (474 aa)
	APZ42_015618	Putative E3 ubiquitin-protein ligase CBL-B. (544 aa)
	APZ42_022454	Putative Ras and Rab interactor 2. (1320 aa)
	APZ42_016095	Tyrosine-protein kinase. (524 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_001425	APZ42_011191	A0A164IZW0	A0A162SGW7	Signal transducer and activator of transcription.	Putative Tyrosine-protein kinase Fps85D.	0.546
APZ42_001425	APZ42_014452	A0A164IZW0	A0A0N8D2H5	Signal transducer and activator of transcription.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.730
APZ42_001425	APZ42_016095	A0A164IZW0	A0A0P6H5F8	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.790
APZ42_001425	APZ42_016105	A0A164IZW0	A0A162NLR5	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.790
APZ42_001425	APZ42_016993	A0A164IZW0	A0A0P6HX98	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.775
APZ42_001425	APZ42_017454	A0A164IZW0	A0A164ZVY8	Signal transducer and activator of transcription.	Cytokine-inducible SH2-containing protein.	0.824
APZ42_001425	APZ42_017933	A0A164IZW0	A0A0N8DDN6	Signal transducer and activator of transcription.	Cytokine-inducible SH2-containing protein.	0.910
APZ42_001425	APZ42_020568	A0A164IZW0	A0A164X7E9	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.912
APZ42_001425	APZ42_022004	A0A164IZW0	A0A0P4WMC5	Signal transducer and activator of transcription.	Putative Tyrosine-protein kinase Btk29A.	0.771
APZ42_001425	APZ42_022197	A0A164IZW0	A0A0P5WQJ9	Signal transducer and activator of transcription.	Putative Cytokine-inducible SH2-containing protein.	0.793
APZ42_001425	APZ42_023748	A0A164IZW0	A0A0N8DE06	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.790
APZ42_001425	APZ42_025681	A0A164IZW0	A0A0P5XZT7	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.569
APZ42_001425	APZ42_030527	A0A164IZW0	A0A164NKL0	Signal transducer and activator of transcription.	Uncharacterized protein.	0.793
APZ42_001425	APZ42_031732	A0A164IZW0	A0A164MLE4	Signal transducer and activator of transcription.	Tyrosine-protein kinase.	0.747
APZ42_011043	APZ42_015040	A0A0P5ZI83	A0A0P5Y732	Rho GTPase activating protein at 5A.	Phosphoinositide phospholipase C.	0.526
APZ42_011043	APZ42_015618	A0A0P5ZI83	A0A0P5CJL7	Rho GTPase activating protein at 5A.	Putative E3 ubiquitin-protein ligase CBL-B.	0.548
APZ42_011043	APZ42_019019	A0A0P5ZI83	A0A0P4XJV0	Rho GTPase activating protein at 5A.	Cytoplasmic protein NCK1.	0.680
APZ42_011043	APZ42_019443	A0A0P5ZI83	A0A164Y7E8	Rho GTPase activating protein at 5A.	Enhancer of sevenless 2B protein.	0.541
APZ42_011043	APZ42_020171	A0A0P5ZI83	A0A164Y277	Rho GTPase activating protein at 5A.	Phosphoinositide phospholipase C.	0.526
APZ42_011191	APZ42_001425	A0A162SGW7	A0A164IZW0	Putative Tyrosine-protein kinase Fps85D.	Signal transducer and activator of transcription.	0.546