(22 nodes) Neurotransmitter clearance network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_013874	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (550 aa)
	APZ42_012095	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (566 aa)
	APZ42_030442	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (635 aa)
	APZ42_031301	MFS domain-containing protein. (991 aa)
	APZ42_023966	Organic cation transporter protein. (620 aa)
	APZ42_015500	Organic cation transporter-like protein. (585 aa)
	APZ42_033263	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (696 aa)
	APZ42_012134	Para-nitrobenzyl esterase. (640 aa)
	APZ42_028521	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa)
	APZ42_033092	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (601 aa)
	APZ42_030891	Solute carrier family 22 member 8. (603 aa)
	APZ42_017931	Organic cation transporter-like protein. (616 aa)
	APZ42_018916	COesterase domain-containing protein. (596 aa)
	APZ42_019266	Carboxylesterase 5A; Belongs to the type-B carboxylesterase/lipase family. (759 aa)
	APZ42_031297	Solute carrier family 22 member 7. (715 aa)
	APZ42_020607	Solute carrier family 22 member 15. (825 aa)
	APZ42_028518	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (507 aa)
	APZ42_029465	Solute carrier family 22 member 7. (545 aa)
	APZ42_030297	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (667 aa)
	APZ42_030311	Uncharacterized protein. (90 aa)
	APZ42_018612	Carboxylic ester hydrolase. (575 aa)
	APZ42_022380	Sodium-dependent serotonin transporter. (506 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_012095	APZ42_018916	A0A162S448	A0A164YY41	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	COesterase domain-containing protein.	0.565
APZ42_012095	APZ42_019266	A0A162S448	A0A164YFM2	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Carboxylesterase 5A; Belongs to the type-B carboxylesterase/lipase family.	0.598
APZ42_012095	APZ42_033263	A0A162S448	A0A164L9D6	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.599
APZ42_012134	APZ42_018916	A0A0P5X902	A0A164YY41	Para-nitrobenzyl esterase.	COesterase domain-containing protein.	0.606
APZ42_012134	APZ42_019266	A0A0P5X902	A0A164YFM2	Para-nitrobenzyl esterase.	Carboxylesterase 5A; Belongs to the type-B carboxylesterase/lipase family.	0.607
APZ42_012134	APZ42_033263	A0A0P5X902	A0A164L9D6	Para-nitrobenzyl esterase.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.607
APZ42_013874	APZ42_018916	A0A162QF36	A0A164YY41	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	COesterase domain-containing protein.	0.568
APZ42_013874	APZ42_019266	A0A162QF36	A0A164YFM2	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Carboxylesterase 5A; Belongs to the type-B carboxylesterase/lipase family.	0.589
APZ42_013874	APZ42_033263	A0A162QF36	A0A164L9D6	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.598
APZ42_015500	APZ42_018916	A0A0P6ABH7	A0A164YY41	Organic cation transporter-like protein.	COesterase domain-containing protein.	0.502
APZ42_015500	APZ42_019266	A0A0P6ABH7	A0A164YFM2	Organic cation transporter-like protein.	Carboxylesterase 5A; Belongs to the type-B carboxylesterase/lipase family.	0.505
APZ42_015500	APZ42_033263	A0A0P6ABH7	A0A164L9D6	Organic cation transporter-like protein.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.505
APZ42_017931	APZ42_018916	A0A164ZFD6	A0A164YY41	Organic cation transporter-like protein.	COesterase domain-containing protein.	0.502
APZ42_017931	APZ42_019266	A0A164ZFD6	A0A164YFM2	Organic cation transporter-like protein.	Carboxylesterase 5A; Belongs to the type-B carboxylesterase/lipase family.	0.505
APZ42_017931	APZ42_033263	A0A164ZFD6	A0A164L9D6	Organic cation transporter-like protein.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.505
APZ42_018612	APZ42_018916	A0A0P5E2A6	A0A164YY41	Carboxylic ester hydrolase.	COesterase domain-containing protein.	0.571
APZ42_018612	APZ42_019266	A0A0P5E2A6	A0A164YFM2	Carboxylic ester hydrolase.	Carboxylesterase 5A; Belongs to the type-B carboxylesterase/lipase family.	0.604
APZ42_018612	APZ42_033263	A0A0P5E2A6	A0A164L9D6	Carboxylic ester hydrolase.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.600
APZ42_018916	APZ42_012095	A0A164YY41	A0A162S448	COesterase domain-containing protein.	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.	0.565
APZ42_018916	APZ42_012134	A0A164YY41	A0A0P5X902	COesterase domain-containing protein.	Para-nitrobenzyl esterase.	0.606