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APZ42_014767 APZ42_014767 EOG090X09LQ EOG090X09LQ APZ42_029459 APZ42_029459 APZ42_018756 APZ42_018756 APZ42_027416 APZ42_027416 APZ42_014562 APZ42_014562 APZ42_013319 APZ42_013319 APZ42_033484 APZ42_033484 APZ42_017923 APZ42_017923 APZ42_022004 APZ42_022004 APZ42_016878 APZ42_016878 APZ42_023819 APZ42_023819 APZ42_011418 APZ42_011418 APZ42_016295 APZ42_016295 APZ42_031728 APZ42_031728 APZ42_030562 APZ42_030562 APZ42_021386 APZ42_021386 EOG090X0BPM EOG090X0BPM APZ42_028069 APZ42_028069 APZ42_019724 APZ42_019724 APZ42_027423 APZ42_027423 APZ42_032613 APZ42_032613 APZ42_026085 APZ42_026085 EOG090X0CE5 EOG090X0CE5 APZ42_031506 APZ42_031506 APZ42_015890 APZ42_015890 APZ42_028172 APZ42_028172 APZ42_022198 APZ42_022198 APZ42_017650 APZ42_017650 APZ42_021635 APZ42_021635 APZ42_012709 APZ42_012709 APZ42_025595 APZ42_025595 APZ42_034381 APZ42_034381 APZ42_028709 APZ42_028709 APZ42_014874 APZ42_014874 APZ42_015342 APZ42_015342 EOG090X05V9 EOG090X05V9 APZ42_015424 APZ42_015424 APZ42_021862 APZ42_021862 APZ42_028388 APZ42_028388 APZ42_013589 APZ42_013589 APZ42_021327 APZ42_021327 APZ42_026380 APZ42_026380 APZ42_020152 APZ42_020152 APZ42_031545 APZ42_031545 APZ42_028289 APZ42_028289 APZ42_028327 APZ42_028327 APZ42_022784 APZ42_022784 APZ42_010923 APZ42_010923 APZ42_019436 APZ42_019436 APZ42_031391 APZ42_031391 APZ42_024450 APZ42_024450 APZ42_009263 APZ42_009263 APZ42_020558 APZ42_020558 APZ42_017921 APZ42_017921 APZ42_017932 APZ42_017932 APZ42_017969 APZ42_017969 APZ42_005840 APZ42_005840 APZ42_030042 APZ42_030042 APZ42_014841 APZ42_014841 EOG090X080D EOG090X080D EOG090X04PU EOG090X04PU APZ42_015256 APZ42_015256 APZ42_015341 APZ42_015341 APZ42_014756 APZ42_014756 APZ42_014663 APZ42_014663 APZ42_013831 APZ42_013831 APZ42_013332 APZ42_013332 APZ42_013012 APZ42_013012 APZ42_012388 APZ42_012388 APZ42_012063 APZ42_012063 APZ42_011549 APZ42_011549 APZ42_011559 APZ42_011559 APZ42_011762 APZ42_011762 APZ42_010980 APZ42_010980 APZ42_005620 APZ42_005620 APZ42_004672 APZ42_004672 APZ42_004212 APZ42_004212 APZ42_002058 APZ42_002058 APZ42_034379 APZ42_034379 APZ42_034375 APZ42_034375 APZ42_034445 APZ42_034445 APZ42_033997 APZ42_033997 APZ42_033270 APZ42_033270 APZ42_032247 APZ42_032247 APZ42_031866 APZ42_031866 APZ42_031574 APZ42_031574 APZ42_031186 APZ42_031186 APZ42_031040 APZ42_031040 APZ42_030508 APZ42_030508 APZ42_030620 APZ42_030620 APZ42_030168 APZ42_030168 APZ42_029320 APZ42_029320 APZ42_028630 APZ42_028630 EOG090X08NC EOG090X08NC APZ42_028305 APZ42_028305 APZ42_028351 APZ42_028351 APZ42_028141 APZ42_028141 APZ42_027128 APZ42_027128 APZ42_027291 APZ42_027291 APZ42_025541 APZ42_025541 APZ42_025209 APZ42_025209 APZ42_023587 APZ42_023587 APZ42_023256 APZ42_023256 APZ42_022879 APZ42_022879 APZ42_022148 APZ42_022148 APZ42_021873 APZ42_021873 APZ42_021729 APZ42_021729 MCM7 MCM7 EOG090X0B66 EOG090X0B66 APZ42_020568 APZ42_020568 APZ42_019954 APZ42_019954 APZ42_018599 APZ42_018599 APZ42_017914 APZ42_017914 EOG090X04UV EOG090X04UV APZ42_017595 APZ42_017595 APZ42_016769 APZ42_016769 APZ42_016194 APZ42_016194
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APZ42_014767Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma. (433 aa)
EOG090X09LQProteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (257 aa)
APZ42_029459Transcription factor E2F4. (283 aa)
APZ42_018756DNA primase; Belongs to the eukaryotic-type primase small subunit family. (405 aa)
APZ42_02741626S proteasome non-ATPase regulatory subunit 14. (311 aa)
APZ42_01456226S proteasome non-ATPase regulatory subunit 9. (203 aa)
APZ42_013319DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (520 aa)
APZ42_033484Proteasome subunit beta. (234 aa)
APZ42_017923Proteasome subunit beta. (276 aa)
APZ42_022004Putative Tyrosine-protein kinase Btk29A. (1513 aa)
APZ42_016878DNA replication factor Cdt1. (705 aa)
APZ42_023819G2/mitotic-specific cyclin-A; Belongs to the cyclin family. (451 aa)
APZ42_011418Replication protein A 32 kDa subunit. (268 aa)
APZ42_016295Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (242 aa)
APZ42_031728Putative 26S proteasome non-ATPase regulatory subunit 3. (496 aa)
APZ42_030562Proteasome activator complex subunit 3. (242 aa)
APZ42_021386Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (255 aa)
EOG090X0BPMCDK-activating kinase assembly factor MAT1. (344 aa)
APZ42_02806926S proteasome regulatory complex subunit p48B; Belongs to the AAA ATPase family. (434 aa)
APZ42_019724Serine/threonine-protein phosphatase. (309 aa)
APZ42_027423DNA helicase; Belongs to the MCM family. (835 aa)
APZ42_032613Replication protein A 14 kDa subunit. (111 aa)
APZ42_026085Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (423 aa)
EOG090X0CE5Proteasome subunit beta. (205 aa)
APZ42_031506Lin-54. (893 aa)
APZ42_015890Origin recognition complex subunit 3. (707 aa)
APZ42_028172Putative Transcription factor E2F4. (452 aa)
APZ42_022198Protein lin-37. (250 aa)
APZ42_017650Histone-binding protein RBBP4. (428 aa)
APZ42_021635Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (234 aa)
APZ42_012709Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (540 aa)
APZ42_025595Proteasome subunit beta. (226 aa)
APZ42_03438126S proteasome non-ATPase regulatory subunit 8. (265 aa)
APZ42_028709Meiosis-specific with OB domain-containing protein. (462 aa)
APZ42_014874Proteasome inhibitor PI31 subunit. (265 aa)
APZ42_015342DNA helicase; Belongs to the MCM family. (843 aa)
EOG090X05V926S proteasome non-ATPase regulatory subunit 13. (379 aa)
APZ42_015424Origin recognition complex subunit. (801 aa)
APZ42_021862Putative DNA polymerase epsilon subunit 4. (128 aa)
APZ42_02838826S proteasome non-ATPase regulatory subunit 6. (389 aa)
APZ42_013589DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2240 aa)
APZ42_021327Fibronectin type III domain-containing protein 3B. (1146 aa)
APZ42_026380Proteasome subunit beta; Belongs to the peptidase T1B family. (262 aa)
APZ42_02015226S proteasome non-ATPase regulatory subunit 11B. (411 aa)
APZ42_03154526S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (929 aa)
APZ42_028289Sensitized chromosome inheritance modifier. (747 aa)
APZ42_028327Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (379 aa)
APZ42_022784Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (285 aa)
APZ42_010923DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (525 aa)
APZ42_01943626S Protease regulatory subunit 4; Belongs to the AAA ATPase family. (442 aa)
APZ42_031391S-phase kinase-associated protein 1; Belongs to the SKP1 family. (162 aa)
APZ42_02445026S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (430 aa)
APZ42_009263Cell division control protein 6. (141 aa)
APZ42_020558Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. (416 aa)
APZ42_017921Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta. (1402 aa)
APZ42_01793226S proteasome non-ATPase regulatory subunit 5. (480 aa)
APZ42_017969Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (83 aa)
APZ42_005840Polyubiquitin-B. (124 aa)
APZ42_030042Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha. (590 aa)
APZ42_014841Cyclin E-like protein; Belongs to the cyclin family. (458 aa)
EOG090X080DEOG090X080D; Belongs to the cyclin family. (328 aa)
EOG090X04PUSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (443 aa)
APZ42_015256Putative M-phase inducer phosphatase. (679 aa)
APZ42_015341Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (250 aa)
APZ42_014756Regulatory particle triple-A ATPase 6-related protein; Belongs to the AAA ATPase family. (404 aa)
APZ42_014663Retinoblastoma family protein. (1077 aa)
APZ42_013831Non-specific serine/threonine protein kinase. (532 aa)
APZ42_013332G1/S-specific cyclin-D2-like protein; Belongs to the cyclin family. (218 aa)
APZ42_013012Proteasome subunit beta. (274 aa)
APZ42_012388DNA helicase; Belongs to the MCM family. (863 aa)
APZ42_012063Putative Cuticle protein. (1206 aa)
APZ42_011549Geminin. (202 aa)
APZ42_011559LisH domain and HEAT repeat-containing protein. (413 aa)
APZ42_011762Putative Serine/threonine-protein phosphatase 4 regulatory subunit 1. (839 aa)
APZ42_010980Protein lin-52. (123 aa)
APZ42_005620Ubiquitin-40S ribosomal protein S27a. (122 aa)
APZ42_004672Cell division control protein 6. (115 aa)
APZ42_00421226S proteasome non-ATPase regulatory subunit 7. (313 aa)
APZ42_002058Serine/threonine-protein kinase minibrain. (266 aa)
APZ42_034379DNA helicase; Belongs to the MCM family. (732 aa)
APZ42_03437526S Protease regulatory subunit 10B; Belongs to the AAA ATPase family. (389 aa)
APZ42_034445Putative MCM8, Minichromosome maintenance complex component 8; Belongs to the MCM family. (593 aa)
APZ42_033997Putative Cyclin-dependent kinase 6. (263 aa)
APZ42_033270Origin recognition complex subunit 2. (340 aa)
APZ42_03224726S Protease regulatory subunit 6B-like protein. (217 aa)
APZ42_031866Putative Serine/threonine-protein phosphatase 4 regulatory subunit 4. (646 aa)
APZ42_031574Reverse transcriptase domain-containing protein. (490 aa)
APZ42_031186CCHC-type domain-containing protein. (505 aa)
APZ42_031040Ubiquitin-60S ribosomal protein L40. (128 aa)
APZ42_03050826S Protease regulatory subunit 6B; Belongs to the AAA ATPase family. (417 aa)
APZ42_030620Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (606 aa)
APZ42_030168Putative DNA polymerase epsilon subunit 3. (141 aa)
APZ42_029320Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (246 aa)
APZ42_028630Proteasome subunit beta type-1. (230 aa)
EOG090X08NC26S proteasome non-ATPase regulatory subunit 4. (388 aa)
APZ42_028305Cyclin_C domain-containing protein. (191 aa)
APZ42_028351DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (698 aa)
APZ42_028141Cyclin D, copy B-like protein; Belongs to the cyclin family. (176 aa)
APZ42_027128Uncharacterized protein. (667 aa)
APZ42_027291DNA polymerase. (1463 aa)
APZ42_025541Protein lin-9. (720 aa)
APZ42_025209DNA helicase; Belongs to the MCM family. (738 aa)
APZ42_023587Origin recognition complex subunit. (417 aa)
APZ42_023256Putative G1/S-specific cyclin-D3; Belongs to the cyclin family. (221 aa)
APZ42_022879WW domain-containing protein. (526 aa)
APZ42_022148Putative Serine/threonine-protein kinase minibrain. (694 aa)
APZ42_021873DNA helicase; Belongs to the MCM family. (811 aa)
APZ42_021729Polyubiquitin-B. (611 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (718 aa)
EOG090X0B66Transcription factor. (447 aa)
APZ42_020568Tyrosine-protein kinase. (587 aa)
APZ42_019954Cell division control protein 45. (581 aa)
APZ42_018599Putative CDK5 and ABL1 enzyme substrate 1. (535 aa)
APZ42_017914Cullin-5; Belongs to the cullin family. (779 aa)
EOG090X04UV26S proteasome non-ATPase regulatory subunit 12. (466 aa)
APZ42_01759526S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (948 aa)
APZ42_016769S-phase kinase-associated protein. (424 aa)
APZ42_016194Uncharacterized protein. (128 aa)
Your Current Organism:
Daphnia magna
NCBI taxonomy Id: 35525
Other names: D. magna
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