(10 nodes) WNT5A-dependent internalization of FZD2, FZD5 and ROR2 network (Daphnia magna)

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Your Input:
	APZ42_020404	Wnt-receptor frizzled variant 1-like protein; Belongs to the G-protein coupled receptor Fz/Smo family. (636 aa)
	APZ42_016802	Secreted frizzled-related protein 2. (394 aa)
	APZ42_015608	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (943 aa)
	APZ42_020788	AP complex subunit beta. (927 aa)
	APZ42_020216	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (228 aa)
	APZ42_018911	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1663 aa)
	APZ42_016099	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
	APZ42_011614	Tyrosine-protein kinase STYK1. (1055 aa)
	APZ42_021443	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (415 aa)
	APZ42_020570	Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (713 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_011614	APZ42_015608	A0A162SVB6	A0A0P5KQ01	Tyrosine-protein kinase STYK1.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.624
APZ42_011614	APZ42_016099	A0A162SVB6	A0A162NMK5	Tyrosine-protein kinase STYK1.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.638
APZ42_011614	APZ42_016802	A0A162SVB6	A0A0P5AXX5	Tyrosine-protein kinase STYK1.	Secreted frizzled-related protein 2.	0.779
APZ42_011614	APZ42_018911	A0A162SVB6	A0A162CQ61	Tyrosine-protein kinase STYK1.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.659
APZ42_011614	APZ42_020216	A0A162SVB6	A0A162CEI2	Tyrosine-protein kinase STYK1.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.639
APZ42_011614	APZ42_020404	A0A162SVB6	A0A0N8BXH8	Tyrosine-protein kinase STYK1.	Wnt-receptor frizzled variant 1-like protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.905
APZ42_011614	APZ42_020570	A0A162SVB6	A0A164X7T0	Tyrosine-protein kinase STYK1.	Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family.	0.905
APZ42_011614	APZ42_021443	A0A162SVB6	A0A164WPI1	Tyrosine-protein kinase STYK1.	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.672
APZ42_015608	APZ42_011614	A0A0P5KQ01	A0A162SVB6	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Tyrosine-protein kinase STYK1.	0.624
APZ42_015608	APZ42_016099	A0A0P5KQ01	A0A162NMK5	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.999
APZ42_015608	APZ42_018911	A0A0P5KQ01	A0A162CQ61	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.969
APZ42_015608	APZ42_020216	A0A0P5KQ01	A0A162CEI2	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.957
APZ42_015608	APZ42_020788	A0A0P5KQ01	A0A0P6DXK2	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	AP complex subunit beta.	0.999
APZ42_015608	APZ42_021443	A0A0P5KQ01	A0A164WPI1	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.999
APZ42_016099	APZ42_011614	A0A162NMK5	A0A162SVB6	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Tyrosine-protein kinase STYK1.	0.638
APZ42_016099	APZ42_015608	A0A162NMK5	A0A0P5KQ01	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.999
APZ42_016099	APZ42_018911	A0A162NMK5	A0A162CQ61	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.933
APZ42_016099	APZ42_020216	A0A162NMK5	A0A162CEI2	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.928
APZ42_016099	APZ42_020788	A0A162NMK5	A0A0P6DXK2	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP complex subunit beta.	0.999
APZ42_016099	APZ42_021443	A0A162NMK5	A0A164WPI1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.999