(81 nodes) Mitotic Prometaphase network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_010960	Uncharacterized protein. (695 aa)
	APZ42_010977	Echinoderm microtubule-associated 4-like protein. (839 aa)
	APZ42_004784	Uncharacterized protein. (124 aa)
	APZ42_002787	Serine/threonine-protein kinase PLK1. (174 aa)
	APZ42_000338	NudC domain-containing protein. (81 aa)
	APZ42_034391	RAP domain-containing protein. (646 aa)
	APZ42_015026	HAUS augmin complex subunit 4-like protein. (328 aa)
	APZ42_033714	LisH domain-containing protein FOPNL. (229 aa)
	APZ42_033185	Centromere protein I. (680 aa)
	APZ42_032610	Gamma-tubulin complex component. (1217 aa)
	APZ42_031762	E3 SUMO-protein ligase RanBP2. (2719 aa)
	APZ42_030704	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (221 aa)
	APZ42_030202	Putative Nuclear pore complex protein Nup98-Nup96. (155 aa)
	APZ42_029033	Stromal antigen, copy A-like protein. (1167 aa)
	APZ42_026726	Structural maintenance of chromosomes protein 3. (1137 aa)
	APZ42_026856	Myosin-Ie; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (943 aa)
	APZ42_025708	Structural maintenance of chromosomes protein. (1215 aa)
	APZ42_023903	Putative Dynactin subunit 1. (1406 aa)
	APZ42_022933	Protein MAD1. (747 aa)
	APZ42_021684	Structural maintenance of chromosomes protein. (1248 aa)
	APZ42_021367	Miniature spindles-like protein. (712 aa)
	APZ42_021266	Gamma-tubulin complex component. (596 aa)
	APZ42_020982	Miniature spindles-like protein. (1145 aa)
	APZ42_020940	Protein kinase domain-containing protein. (114 aa)
	APZ42_019858	Serine/threonine-protein kinase PLK. (650 aa)
	APZ42_019849	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (365 aa)
	APZ42_019645	Cytosol aminopeptidase. (495 aa)
	APZ42_019176	Gamma-tubulin complex component. (696 aa)
	APZ42_019002	Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (462 aa)
	APZ42_018521	Dynactin subunit 1. (275 aa)
	APZ42_018091	Pds5. (1365 aa)
	APZ42_017941	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (256 aa)
	APZ42_016670	Uncharacterized protein. (624 aa)
	APZ42_016880	Grip71. (558 aa)
	APZ42_017023	Uncharacterized protein. (533 aa)
	APZ42_034438	Structural maintenance of chromosomes protein. (1311 aa)
	APZ42_014881	Condensin complex subunit 3. (1070 aa)
	APZ42_016054	Uncharacterized protein. (655 aa)
	APZ42_015847	HAUS6_N domain-containing protein. (774 aa)
	APZ42_026287	Putative Rootletin. (1415 aa)
	APZ42_023265	Serine/threonine-protein kinase PLK. (584 aa)
	APZ42_017869	Putative Aminopeptidase NPEPL1. (529 aa)
	APZ42_018314	Blastoderm-specific protein 25D. (1121 aa)
	APZ42_023451	Serine/threonine-protein kinase PLK4. (805 aa)
	APZ42_030556	G2/mitotic-specific cyclin protein, copy A; Belongs to the cyclin family. (420 aa)
	APZ42_015882	NADPH--cytochrome P450 reductase protein. (1967 aa)
	APZ42_011811	Putative Spindle assembly abnormal 4. (873 aa)
	APZ42_027204	Sodium/hydrogen exchanger. (263 aa)
	APZ42_014875	Golgin subfamily A member. (1404 aa)
	APZ42_033476	Microtubule-associated protein RP/EB family member. (291 aa)
	APZ42_019766	G2/mitotic-specific cyclin B, copy B-like protein; Belongs to the cyclin family. (410 aa)
	APZ42_013274	Zwilch. (574 aa)
	APZ42_032827	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (611 aa)
	APZ42_012386	Gamma-tubulin complex component. (869 aa)
	APZ42_011172	Putative Centrosomal protein of 78 kDa. (743 aa)
	APZ42_025764	Uncharacterized protein. (981 aa)
	APZ42_010950	Double-strand-break repair protein rad21. (753 aa)
	APZ42_015224	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (717 aa)
	APZ42_028812	Uncharacterized protein. (80 aa)
	APZ42_029322	Centrosomal protein of 41 kDa. (248 aa)
	APZ42_015149	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (476 aa)
	APZ42_017814	HAUS augmin complex subunit 3-like protein. (598 aa)
	APZ42_017329	Nuclear distribution protein nudE 1-B. (307 aa)
	APZ42_029766	Wings apart protein. (1109 aa)
	APZ42_026105	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1453 aa)
	APZ42_014953	Centrosomal protein of 164 kDa. (1104 aa)
	APZ42_021091	Kinetochore associated 2. (619 aa)
	APZ42_019904	G2/mitotic-specific cyclin-B3; Belongs to the cyclin family. (410 aa)
	APZ42_023909	Nucleoside diphosphate kinase. (398 aa)
	APZ42_019239	Serologically defined colon cancer antigen. (515 aa)
	APZ42_027250	Structural maintenance of chromosomes protein. (1207 aa)
	APZ42_013202	Aminopeptidase W07G4.4. (431 aa)
	EOG090X0AH4	Nuclear migration protein nudC. (320 aa)
	APZ42_012464	Putative RNA-binding protein 38; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1283 aa)
	APZ42_012480	Gamma-tubulin complex component. (571 aa)
	APZ42_012050	B9d2. (806 aa)
	APZ42_012251	UPF0582 protein. (96 aa)
	APZ42_011257	Serine/threonine-protein kinase Nek6; Belongs to the protein kinase superfamily. (470 aa)
	APZ42_010944	CLIP-associating protein. (805 aa)
	APZ42_015455	Rough deal. (1953 aa)
	APZ42_015339	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_000338	APZ42_002787	A0A164JR54	A0A164I1J4	NudC domain-containing protein.	Serine/threonine-protein kinase PLK1.	0.609
APZ42_000338	APZ42_010944	A0A164JR54	A0A162TBN6	NudC domain-containing protein.	CLIP-associating protein.	0.710
APZ42_000338	APZ42_010977	A0A164JR54	A0A162TCZ6	NudC domain-containing protein.	Echinoderm microtubule-associated 4-like protein.	0.671
APZ42_000338	APZ42_013274	A0A164JR54	A0A0P5UIS9	NudC domain-containing protein.	Zwilch.	0.635
APZ42_000338	APZ42_015149	A0A164JR54	A0A0P5K224	NudC domain-containing protein.	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit.	0.538
APZ42_000338	APZ42_015339	A0A164JR54	A0A162PE16	NudC domain-containing protein.	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.	0.522
APZ42_000338	APZ42_017329	A0A164JR54	A0A0P5EH87	NudC domain-containing protein.	Nuclear distribution protein nudE 1-B.	0.789
APZ42_000338	APZ42_018314	A0A164JR54	A0A0P5ZL95	NudC domain-containing protein.	Blastoderm-specific protein 25D.	0.516
APZ42_000338	APZ42_019858	A0A164JR54	A0A164XS43	NudC domain-containing protein.	Serine/threonine-protein kinase PLK.	0.609
APZ42_000338	APZ42_020940	A0A164JR54	A0A164X432	NudC domain-containing protein.	Protein kinase domain-containing protein.	0.609
APZ42_000338	APZ42_021091	A0A164JR54	A0A0P4Z8I4	NudC domain-containing protein.	Kinetochore associated 2.	0.620
APZ42_000338	APZ42_022933	A0A164JR54	A0A164VAW4	NudC domain-containing protein.	Protein MAD1.	0.678
APZ42_000338	APZ42_023265	A0A164JR54	A0A0P6FEB9	NudC domain-containing protein.	Serine/threonine-protein kinase PLK.	0.609
APZ42_000338	APZ42_023451	A0A164JR54	A0A0P5ZIA8	NudC domain-containing protein.	Serine/threonine-protein kinase PLK4.	0.609
APZ42_000338	APZ42_031762	A0A164JR54	A0A164MMU2	NudC domain-containing protein.	E3 SUMO-protein ligase RanBP2.	0.977
APZ42_000338	APZ42_032827	A0A164JR54	A0A0P5UID6	NudC domain-containing protein.	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit.	0.538
APZ42_000338	APZ42_033185	A0A164JR54	A0A164LBC8	NudC domain-containing protein.	Centromere protein I.	0.522
APZ42_002787	APZ42_000338	A0A164I1J4	A0A164JR54	Serine/threonine-protein kinase PLK1.	NudC domain-containing protein.	0.609
APZ42_002787	APZ42_010944	A0A164I1J4	A0A162TBN6	Serine/threonine-protein kinase PLK1.	CLIP-associating protein.	0.679
APZ42_002787	APZ42_010950	A0A164I1J4	A0A0P5KPJ4	Serine/threonine-protein kinase PLK1.	Double-strand-break repair protein rad21.	0.958