STRINGSTRING
APZ42_034379 APZ42_034379 EOG090X09LQ EOG090X09LQ APZ42_018756 APZ42_018756 APZ42_027416 APZ42_027416 APZ42_014562 APZ42_014562 APZ42_013319 APZ42_013319 APZ42_033484 APZ42_033484 APZ42_019262 APZ42_019262 APZ42_017923 APZ42_017923 APZ42_016878 APZ42_016878 APZ42_030313 APZ42_030313 APZ42_023819 APZ42_023819 APZ42_011418 APZ42_011418 APZ42_016295 APZ42_016295 APZ42_031728 APZ42_031728 APZ42_030562 APZ42_030562 APZ42_021386 APZ42_021386 APZ42_032406 APZ42_032406 Fen1 Fen1 APZ42_012437 APZ42_012437 APZ42_028069 APZ42_028069 APZ42_027423 APZ42_027423 APZ42_033296 APZ42_033296 EOG090X0DZY EOG090X0DZY APZ42_020996 APZ42_020996 APZ42_032613 APZ42_032613 APZ42_026085 APZ42_026085 EOG090X0CE5 EOG090X0CE5 APZ42_033980 APZ42_033980 APZ42_029240 APZ42_029240 EOG090X0G8U EOG090X0G8U APZ42_020989 APZ42_020989 APZ42_015890 APZ42_015890 APZ42_021635 APZ42_021635 APZ42_022261 APZ42_022261 APZ42_025595 APZ42_025595 APZ42_030968 APZ42_030968 APZ42_034381 APZ42_034381 APZ42_022929 APZ42_022929 APZ42_028709 APZ42_028709 APZ42_014874 APZ42_014874 APZ42_012380 APZ42_012380 APZ42_015342 APZ42_015342 EOG090X05V9 EOG090X05V9 APZ42_015424 APZ42_015424 APZ42_021862 APZ42_021862 APZ42_028388 APZ42_028388 APZ42_013589 APZ42_013589 APZ42_012799 APZ42_012799 APZ42_026380 APZ42_026380 APZ42_020152 APZ42_020152 APZ42_031545 APZ42_031545 APZ42_020411 APZ42_020411 APZ42_028289 APZ42_028289 APZ42_018670 APZ42_018670 APZ42_022784 APZ42_022784 APZ42_010923 APZ42_010923 APZ42_019436 APZ42_019436 APZ42_031391 APZ42_031391 APZ42_024450 APZ42_024450 APZ42_021587 APZ42_021587 APZ42_011351 APZ42_011351 APZ42_004607 APZ42_004607 APZ42_009263 APZ42_009263 APZ42_020612 APZ42_020612 APZ42_017932 APZ42_017932 APZ42_005840 APZ42_005840 APZ42_004333 APZ42_004333 APZ42_001774 APZ42_001774 APZ42_028882 APZ42_028882 APZ42_014841 APZ42_014841 APZ42_014888 APZ42_014888 APZ42_015341 APZ42_015341 APZ42_014756 APZ42_014756 APZ42_013012 APZ42_013012 APZ42_012850 APZ42_012850 APZ42_012388 APZ42_012388 APZ42_012063 APZ42_012063 APZ42_012142 APZ42_012142 APZ42_012136 APZ42_012136 APZ42_011260 APZ42_011260 APZ42_011549 APZ42_011549 APZ42_010927 APZ42_010927 APZ42_005620 APZ42_005620 APZ42_004672 APZ42_004672 APZ42_004212 APZ42_004212 APZ42_000083 APZ42_000083 APZ42_034375 APZ42_034375 APZ42_034445 APZ42_034445 APZ42_033270 APZ42_033270 APZ42_033198 APZ42_033198 APZ42_032633 APZ42_032633 APZ42_032247 APZ42_032247 APZ42_031574 APZ42_031574 APZ42_031273 APZ42_031273 APZ42_031186 APZ42_031186 APZ42_031040 APZ42_031040 APZ42_030508 APZ42_030508 APZ42_030620 APZ42_030620 APZ42_030168 APZ42_030168 APZ42_029320 APZ42_029320 APZ42_029021 APZ42_029021 APZ42_028630 APZ42_028630 EOG090X08NC EOG090X08NC APZ42_028351 APZ42_028351 APZ42_028384 APZ42_028384 APZ42_028029 APZ42_028029 APZ42_027270 APZ42_027270 APZ42_027291 APZ42_027291 APZ42_025209 APZ42_025209 APZ42_023887 APZ42_023887 APZ42_023587 APZ42_023587 APZ42_022066 APZ42_022066 APZ42_021873 APZ42_021873 APZ42_021729 APZ42_021729 MCM7 MCM7 APZ42_021143 APZ42_021143 APZ42_019954 APZ42_019954 APZ42_019138 APZ42_019138 APZ42_018111 APZ42_018111 APZ42_017914 APZ42_017914 EOG090X04UV EOG090X04UV APZ42_017595 APZ42_017595 APZ42_016769 APZ42_016769 APZ42_017012 APZ42_017012 APZ42_016194 APZ42_016194
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APZ42_034379DNA helicase; Belongs to the MCM family. (732 aa)
EOG090X09LQProteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (257 aa)
APZ42_018756DNA primase; Belongs to the eukaryotic-type primase small subunit family. (405 aa)
APZ42_02741626S proteasome non-ATPase regulatory subunit 14. (311 aa)
APZ42_01456226S proteasome non-ATPase regulatory subunit 9. (203 aa)
APZ42_013319DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (520 aa)
APZ42_033484Proteasome subunit beta. (234 aa)
APZ42_019262RCC1 and BTB domain-containing protein 1. (530 aa)
APZ42_017923Proteasome subunit beta. (276 aa)
APZ42_016878DNA replication factor Cdt1. (705 aa)
APZ42_030313Anaphase-promoting complex subunit 7. (560 aa)
APZ42_023819G2/mitotic-specific cyclin-A; Belongs to the cyclin family. (451 aa)
APZ42_011418Replication protein A 32 kDa subunit. (268 aa)
APZ42_016295Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (242 aa)
APZ42_031728Putative 26S proteasome non-ATPase regulatory subunit 3. (496 aa)
APZ42_030562Proteasome activator complex subunit 3. (242 aa)
APZ42_021386Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (255 aa)
APZ42_032406Anaphase-promoting complex subunit. (120 aa)
Fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (381 aa)
APZ42_012437Replication factor C subunit 3. (328 aa)
APZ42_02806926S proteasome regulatory complex subunit p48B; Belongs to the AAA ATPase family. (434 aa)
APZ42_027423DNA helicase; Belongs to the MCM family. (835 aa)
APZ42_033296Protein FAM89A-like protein. (159 aa)
EOG090X0DZYUbiquitin-conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (176 aa)
APZ42_020996Uncharacterized protein. (529 aa)
APZ42_032613Replication protein A 14 kDa subunit. (111 aa)
APZ42_026085Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (423 aa)
EOG090X0CE5Proteasome subunit beta. (205 aa)
APZ42_033980Replication factor C subunit 1. (1083 aa)
APZ42_029240Cell division cycle protein 27. (863 aa)
EOG090X0G8UDNA replication complex GINS protein PSF3. (202 aa)
APZ42_020989Transmembrane 7 superfamily member 3. (555 aa)
APZ42_015890Origin recognition complex subunit 3. (707 aa)
APZ42_021635Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (234 aa)
APZ42_022261Anaphase promoting complex subunit 4. (775 aa)
APZ42_025595Proteasome subunit beta. (226 aa)
APZ42_030968Ubiquitin-conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family. (301 aa)
APZ42_03438126S proteasome non-ATPase regulatory subunit 8. (265 aa)
APZ42_022929DNA polymerase. (1088 aa)
APZ42_028709Meiosis-specific with OB domain-containing protein. (462 aa)
APZ42_014874Proteasome inhibitor PI31 subunit. (265 aa)
APZ42_012380Importin subunit alpha-1. (534 aa)
APZ42_015342DNA helicase; Belongs to the MCM family. (843 aa)
EOG090X05V926S proteasome non-ATPase regulatory subunit 13. (379 aa)
APZ42_015424Origin recognition complex subunit. (801 aa)
APZ42_021862Putative DNA polymerase epsilon subunit 4. (128 aa)
APZ42_02838826S proteasome non-ATPase regulatory subunit 6. (389 aa)
APZ42_013589DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2240 aa)
APZ42_012799Anaphase-promoting complex subunit 2; Belongs to the cullin family. (768 aa)
APZ42_026380Proteasome subunit beta; Belongs to the peptidase T1B family. (262 aa)
APZ42_02015226S proteasome non-ATPase regulatory subunit 11B. (411 aa)
APZ42_03154526S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (929 aa)
APZ42_020411Cell division cycle protein 23. (569 aa)
APZ42_028289Sensitized chromosome inheritance modifier. (747 aa)
APZ42_018670Karyopherin importin beta. (885 aa)
APZ42_022784Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (285 aa)
APZ42_010923DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (525 aa)
APZ42_01943626S Protease regulatory subunit 4; Belongs to the AAA ATPase family. (442 aa)
APZ42_031391S-phase kinase-associated protein 1; Belongs to the SKP1 family. (162 aa)
APZ42_02445026S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (430 aa)
APZ42_021587Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (192 aa)
APZ42_011351Cell division cycle protein 16. (671 aa)
APZ42_004607Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
APZ42_009263Cell division control protein 6. (141 aa)
APZ42_020612DNA replication ATP-dependent helicase/nuclease DNA2. (765 aa)
APZ42_01793226S proteasome non-ATPase regulatory subunit 5. (480 aa)
APZ42_005840Polyubiquitin-B. (124 aa)
APZ42_004333Replication factor C subunit 3. (331 aa)
APZ42_001774Uncharacterized protein. (97 aa)
APZ42_028882DNA ligase. (816 aa)
APZ42_014841Cyclin E-like protein; Belongs to the cyclin family. (458 aa)
APZ42_014888Anaphase-promoting complex subunit 5. (759 aa)
APZ42_015341Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (250 aa)
APZ42_014756Regulatory particle triple-A ATPase 6-related protein; Belongs to the AAA ATPase family. (404 aa)
APZ42_013012Proteasome subunit beta. (274 aa)
APZ42_012850Ubiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (460 aa)
APZ42_012388DNA helicase; Belongs to the MCM family. (863 aa)
APZ42_012063Putative Cuticle protein. (1206 aa)
APZ42_012142Proteasome activator complex subunit. (674 aa)
APZ42_012136Proteasome activator complex subunit. (1077 aa)
APZ42_011260Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (381 aa)
APZ42_011549Geminin. (202 aa)
APZ42_010927Replication factor C subunit 2. (288 aa)
APZ42_005620Ubiquitin-40S ribosomal protein S27a. (122 aa)
APZ42_004672Cell division control protein 6. (115 aa)
APZ42_00421226S proteasome non-ATPase regulatory subunit 7. (313 aa)
APZ42_000083Replication factor C subunit 4. (98 aa)
APZ42_03437526S Protease regulatory subunit 10B; Belongs to the AAA ATPase family. (389 aa)
APZ42_034445Putative MCM8, Minichromosome maintenance complex component 8; Belongs to the MCM family. (593 aa)
APZ42_033270Origin recognition complex subunit 2. (340 aa)
APZ42_033198DNA polymerase delta small subunit. (444 aa)
APZ42_032633RING-box protein 1A. (116 aa)
APZ42_03224726S Protease regulatory subunit 6B-like protein. (217 aa)
APZ42_031574Reverse transcriptase domain-containing protein. (490 aa)
APZ42_031273Replication factor C subunit 2. (344 aa)
APZ42_031186CCHC-type domain-containing protein. (505 aa)
APZ42_031040Ubiquitin-60S ribosomal protein L40. (128 aa)
APZ42_03050826S Protease regulatory subunit 6B; Belongs to the AAA ATPase family. (417 aa)
APZ42_030620Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (606 aa)
APZ42_030168Putative DNA polymerase epsilon subunit 3. (141 aa)
APZ42_029320Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family. (246 aa)
APZ42_029021Importin subunit alpha; Belongs to the importin alpha family. (519 aa)
APZ42_028630Proteasome subunit beta type-1. (230 aa)
EOG090X08NC26S proteasome non-ATPase regulatory subunit 4. (388 aa)
APZ42_028351DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (698 aa)
APZ42_028384Importin subunit beta. (888 aa)
APZ42_028029GLTSCR1 domain-containing protein. (1336 aa)
APZ42_027270DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (248 aa)
APZ42_027291DNA polymerase. (1463 aa)
APZ42_025209DNA helicase; Belongs to the MCM family. (738 aa)
APZ42_023887Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (146 aa)
APZ42_023587Origin recognition complex subunit. (417 aa)
APZ42_022066Putative Importin subunit beta-1. (588 aa)
APZ42_021873DNA helicase; Belongs to the MCM family. (811 aa)
APZ42_021729Polyubiquitin-B. (611 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (718 aa)
APZ42_021143DNA polymerase delta subunit 3. (448 aa)
APZ42_019954Cell division control protein 45. (581 aa)
APZ42_019138ATPase_AAA_core domain-containing protein. (897 aa)
APZ42_018111Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
APZ42_017914Cullin-5; Belongs to the cullin family. (779 aa)
EOG090X04UV26S proteasome non-ATPase regulatory subunit 12. (466 aa)
APZ42_01759526S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (948 aa)
APZ42_016769S-phase kinase-associated protein. (424 aa)
APZ42_017012Anaphase-promoting complex subunit 1. (1935 aa)
APZ42_016194Uncharacterized protein. (128 aa)
Your Current Organism:
Daphnia magna
NCBI taxonomy Id: 35525
Other names: D. magna
Server load: low (18%) [HD]