(55 nodes) mRNA Splicing - Minor Pathway network (Daphnia magna)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	APZ42_011146	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (124 aa)
	APZ42_017655	DNA-directed RNA polymerases I, II, and III subunit RPABC2. (129 aa)
	APZ42_013664	Putative Serine/arginine-rich splicing factor 2. (235 aa)
	APZ42_027607	Putative Splicing factor 3B subunit 2. (678 aa)
	APZ42_028383	Small nuclear ribonucleoprotein-associated protein. (234 aa)
	EOG090X017X	Pre-mRNA-processing factor 6. (926 aa)
	APZ42_032863	Small nuclear ribonucleoprotein F; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (88 aa)
	EOG090X0PCK	DNA-directed RNA polymerases I, II, and III subunit RPABC5. (67 aa)
	APZ42_018093	Putative ATP-dependent RNA helicase DDX52. (821 aa)
	APZ42_032652	Pre-mRNA branch site p14 protein. (122 aa)
	APZ42_011579	Nuclear cap-binding protein subunit 1. (809 aa)
	APZ42_034342	U5 small nuclear ribonucleoprotein 40 kDa protein. (337 aa)
	APZ42_016996	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
	APZ42_015980	Pre-mRNA-processing-splicing factor 8. (2403 aa)
	APZ42_020879	Splicing factor 3B subunit 4. (299 aa)
	APZ42_028116	ATP-dependent RNA helicase DDX42. (802 aa)
	APZ42_018810	Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (85 aa)
	APZ42_012093	DNA-directed RNA polymerase II subunit RPB3. (274 aa)
	EOG090X00RJ	116 kDa U5 small nuclear ribonucleoprotein component protein. (982 aa)
	APZ42_017061	DNA-directed RNA polymerase II subunit RPB7. (172 aa)
	APZ42_011824	Uncharacterized protein. (153 aa)
	APZ42_021634	Serine/arginine-rich splicing factor. (162 aa)
	APZ42_022464	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (151 aa)
	APZ42_002383	Putative DNA-directed RNA polymerase subunit beta. (107 aa)
	APZ42_000712	Splicing factor 3B subunit. (74 aa)
	APZ42_032857	DNA damage-binding protein 1. (1215 aa)
	APZ42_004441	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (133 aa)
	APZ42_016009	RNA-binding protein 40. (431 aa)
	APZ42_015312	Uncharacterized protein. (565 aa)
	APZ42_013549	Small nuclear ribonucleoprotein G. (77 aa)
	APZ42_012307	Putative Cold-shock DNA-binding family protein. (321 aa)
	APZ42_005758	DNA-directed RNA polymerase subunit beta. (86 aa)
	APZ42_005682	Putative DNA-directed RNA polymerase subunit beta. (88 aa)
	APZ42_005470	Putative DNA-directed RNA polymerase subunit beta. (120 aa)
	APZ42_003221	Putative DNA-directed RNA polymerase subunit beta. (107 aa)
	APZ42_000020	Serine/arginine-rich splicing factor 1. (209 aa)
	APZ42_034473	Splicing factor 3B subunit 1. (1306 aa)
	APZ42_032471	C3H1-type domain-containing protein. (150 aa)
	APZ42_032322	U11/U12 small nuclear ribonucleoprotein 25 kDa protein. (211 aa)
	EOG090X0J86	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (127 aa)
	APZ42_029692	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (268 aa)
	APZ42_029594	Putative U5 small nuclear ribonucleoprotein 200 kDa helicase. (2155 aa)
	APZ42_029321	Small nuclear ribonucleoprotein Sm D2. (78 aa)
	APZ42_029253	Uncharacterized protein. (322 aa)
	APZ42_028255	DNA-directed RNA polymerases I. (265 aa)
	APZ42_026494	DNA-directed RNA polymerases I, II, and III subunit RPABC4. (59 aa)
	APZ42_026363	Zinc finger CCHC-type and RNA-binding motif-containing protein 1. (194 aa)
	APZ42_021683	Putative RNA-binding protein 1. (164 aa)
	APZ42_021155	Uncharacterized protein. (361 aa)
	APZ42_020155	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (94 aa)
	APZ42_020217	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary microRNAs (miRNAs) processing. Also involved in innate immunity via the short interfering RNAs (siRNAs) processing machinery by restricting the viral RNA production. In the CBC complex, Cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requ [...] (151 aa)
	EOG090X0NFO	Small nuclear ribonucleoprotein Sm D3. (141 aa)
	APZ42_019320	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (546 aa)
	APZ42_017703	DNA-directed RNA polymerase; Belongs to the RNA polymerase beta chain family. (775 aa)
	APZ42_017597	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1454 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_000020	APZ42_000712	A0A164JZ53	A0A162C900	Serine/arginine-rich splicing factor 1.	Splicing factor 3B subunit.	0.878
APZ42_000020	APZ42_002383	A0A164JZ53	A0A162C5A5	Serine/arginine-rich splicing factor 1.	Putative DNA-directed RNA polymerase subunit beta.	0.646
APZ42_000020	APZ42_003221	A0A164JZ53	A0A164HQ48	Serine/arginine-rich splicing factor 1.	Putative DNA-directed RNA polymerase subunit beta.	0.646
APZ42_000020	APZ42_004441	A0A164JZ53	A0A162F0G2	Serine/arginine-rich splicing factor 1.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.646
APZ42_000020	APZ42_005470	A0A164JZ53	A0A164GFE1	Serine/arginine-rich splicing factor 1.	Putative DNA-directed RNA polymerase subunit beta.	0.646
APZ42_000020	APZ42_005682	A0A164JZ53	A0A164GBF9	Serine/arginine-rich splicing factor 1.	Putative DNA-directed RNA polymerase subunit beta.	0.646
APZ42_000020	APZ42_005758	A0A164JZ53	A0A164G9T6	Serine/arginine-rich splicing factor 1.	DNA-directed RNA polymerase subunit beta.	0.646
APZ42_000020	APZ42_011146	A0A164JZ53	A0A0N8DC65	Serine/arginine-rich splicing factor 1.	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	0.884
APZ42_000020	APZ42_011579	A0A164JZ53	A0A0P5IV70	Serine/arginine-rich splicing factor 1.	Nuclear cap-binding protein subunit 1.	0.931
APZ42_000020	APZ42_011824	A0A164JZ53	A0A0P6E209	Serine/arginine-rich splicing factor 1.	Uncharacterized protein.	0.674
APZ42_000020	APZ42_012093	A0A164JZ53	A0A0P5ZDC7	Serine/arginine-rich splicing factor 1.	DNA-directed RNA polymerase II subunit RPB3.	0.788
APZ42_000020	APZ42_012307	A0A164JZ53	A0A162RYG9	Serine/arginine-rich splicing factor 1.	Putative Cold-shock DNA-binding family protein.	0.743
APZ42_000020	APZ42_013549	A0A164JZ53	A0A162QM09	Serine/arginine-rich splicing factor 1.	Small nuclear ribonucleoprotein G.	0.893
APZ42_000020	APZ42_013664	A0A164JZ53	A0A0P4XPR5	Serine/arginine-rich splicing factor 1.	Putative Serine/arginine-rich splicing factor 2.	0.998
APZ42_000020	APZ42_015312	A0A164JZ53	A0A162PD60	Serine/arginine-rich splicing factor 1.	Uncharacterized protein.	0.861
APZ42_000020	APZ42_015980	A0A164JZ53	A0A0P5R8V3	Serine/arginine-rich splicing factor 1.	Pre-mRNA-processing-splicing factor 8.	0.752
APZ42_000020	APZ42_016009	A0A164JZ53	A0A162NIS1	Serine/arginine-rich splicing factor 1.	RNA-binding protein 40.	0.677
APZ42_000020	APZ42_017061	A0A164JZ53	A0A0P6DZI8	Serine/arginine-rich splicing factor 1.	DNA-directed RNA polymerase II subunit RPB7.	0.721
APZ42_000020	APZ42_017597	A0A164JZ53	A0A164ZZ64	Serine/arginine-rich splicing factor 1.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.674
APZ42_000020	APZ42_017655	A0A164JZ53	A0A0N8ENC8	Serine/arginine-rich splicing factor 1.	DNA-directed RNA polymerases I, II, and III subunit RPABC2.	0.741