(11 nodes) Depurination network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_023717	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (490 aa)
	APZ42_003939	DNA-3-methyladenine glycosylase. (73 aa)
	APZ42_011474	TM2 domain-containing protein almondex. (211 aa)
	APZ42_001774	Uncharacterized protein. (97 aa)
	APZ42_015561	N-glycosylase/DNA lyase. (350 aa)
	APZ42_000307	Putative DNA-3-methyladenine glycosylase. (140 aa)
	APZ42_029243	Uncharacterized protein. (1185 aa)
	APZ42_028745	Uncharacterized protein. (1018 aa)
	APZ42_023887	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (146 aa)
	APZ42_011260	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (381 aa)
	APZ42_004607	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_000307	APZ42_015561	A0A162C9N3	A0A162NVS3	Putative DNA-3-methyladenine glycosylase.	N-glycosylase/DNA lyase.	0.455
APZ42_001774	APZ42_004607	A0A162CZU8	A0A0P6INX3	Uncharacterized protein.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.770
APZ42_001774	APZ42_011260	A0A162CZU8	A0A162SIV5	Uncharacterized protein.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.770
APZ42_001774	APZ42_023887	A0A162CZU8	A0A164U839	Uncharacterized protein.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.770
APZ42_001774	APZ42_028745	A0A162CZU8	A0A164QBR0	Uncharacterized protein.	Uncharacterized protein.	0.487
APZ42_003939	APZ42_015561	A0A164HCA4	A0A162NVS3	DNA-3-methyladenine glycosylase.	N-glycosylase/DNA lyase.	0.455
APZ42_004607	APZ42_001774	A0A0P6INX3	A0A162CZU8	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	Uncharacterized protein.	0.770
APZ42_004607	APZ42_028745	A0A0P6INX3	A0A164QBR0	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	Uncharacterized protein.	0.544
APZ42_011260	APZ42_001774	A0A162SIV5	A0A162CZU8	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	Uncharacterized protein.	0.770
APZ42_011260	APZ42_028745	A0A162SIV5	A0A164QBR0	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	Uncharacterized protein.	0.544
APZ42_011474	APZ42_028745	A0A162CZB4	A0A164QBR0	TM2 domain-containing protein almondex.	Uncharacterized protein.	0.600
APZ42_015561	APZ42_000307	A0A162NVS3	A0A162C9N3	N-glycosylase/DNA lyase.	Putative DNA-3-methyladenine glycosylase.	0.455
APZ42_015561	APZ42_003939	A0A162NVS3	A0A164HCA4	N-glycosylase/DNA lyase.	DNA-3-methyladenine glycosylase.	0.455
APZ42_015561	APZ42_023717	A0A162NVS3	A0A164UQ45	N-glycosylase/DNA lyase.	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	0.612
APZ42_023717	APZ42_015561	A0A164UQ45	A0A162NVS3	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	N-glycosylase/DNA lyase.	0.612
APZ42_023887	APZ42_001774	A0A164U839	A0A162CZU8	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	Uncharacterized protein.	0.770
APZ42_023887	APZ42_028745	A0A164U839	A0A164QBR0	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	Uncharacterized protein.	0.544
APZ42_028745	APZ42_001774	A0A164QBR0	A0A162CZU8	Uncharacterized protein.	Uncharacterized protein.	0.487
APZ42_028745	APZ42_004607	A0A164QBR0	A0A0P6INX3	Uncharacterized protein.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.544
APZ42_028745	APZ42_011260	A0A164QBR0	A0A162SIV5	Uncharacterized protein.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.544