(11 nodes) RUNX3 regulates p14-ARF network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_032315	Putative TGF-beta ligand Decapentaplegic protein. (466 aa)
	APZ42_028305	Cyclin_C domain-containing protein. (191 aa)
	APZ42_028141	Cyclin D, copy B-like protein; Belongs to the cyclin family. (176 aa)
	APZ42_023256	Putative G1/S-specific cyclin-D3; Belongs to the cyclin family. (221 aa)
	APZ42_027338	Putative CREB-binding protein. (2063 aa)
	APZ42_013271	Putative Bromodomain testis-specific protein. (1476 aa)
	APZ42_020282	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1140 aa)
	APZ42_018132	Ras protein 1. (190 aa)
	APZ42_028336	Core-binding factor subunit beta. (233 aa)
	APZ42_022790	Uncharacterized protein. (1061 aa)
	APZ42_033023	Putative TGF-beta ligand glass bottom boat protein. (459 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_013271	APZ42_020282	A0A0P4XCN3	A0A0P5BZJ2	Putative Bromodomain testis-specific protein.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.431
APZ42_013271	APZ42_022790	A0A0P4XCN3	A0A162C899	Putative Bromodomain testis-specific protein.	Uncharacterized protein.	0.581
APZ42_013271	APZ42_027338	A0A0P4XCN3	A0A164RHI9	Putative Bromodomain testis-specific protein.	Putative CREB-binding protein.	0.581
APZ42_013271	APZ42_028336	A0A0P4XCN3	A0A0P6CM72	Putative Bromodomain testis-specific protein.	Core-binding factor subunit beta.	0.573
APZ42_020282	APZ42_013271	A0A0P5BZJ2	A0A0P4XCN3	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Putative Bromodomain testis-specific protein.	0.431
APZ42_020282	APZ42_022790	A0A0P5BZJ2	A0A162C899	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Uncharacterized protein.	0.621
APZ42_020282	APZ42_023256	A0A0P5BZJ2	A0A164V3I3	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Putative G1/S-specific cyclin-D3; Belongs to the cyclin family.	0.605
APZ42_020282	APZ42_027338	A0A0P5BZJ2	A0A164RHI9	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Putative CREB-binding protein.	0.621
APZ42_020282	APZ42_028141	A0A0P5BZJ2	A0A164QSS8	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Cyclin D, copy B-like protein; Belongs to the cyclin family.	0.605
APZ42_020282	APZ42_028305	A0A0P5BZJ2	A0A164QNL0	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Cyclin_C domain-containing protein.	0.605
APZ42_022790	APZ42_013271	A0A162C899	A0A0P4XCN3	Uncharacterized protein.	Putative Bromodomain testis-specific protein.	0.581
APZ42_022790	APZ42_020282	A0A162C899	A0A0P5BZJ2	Uncharacterized protein.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.621
APZ42_022790	APZ42_023256	A0A162C899	A0A164V3I3	Uncharacterized protein.	Putative G1/S-specific cyclin-D3; Belongs to the cyclin family.	0.649
APZ42_022790	APZ42_028141	A0A162C899	A0A164QSS8	Uncharacterized protein.	Cyclin D, copy B-like protein; Belongs to the cyclin family.	0.649
APZ42_022790	APZ42_028305	A0A162C899	A0A164QNL0	Uncharacterized protein.	Cyclin_C domain-containing protein.	0.649
APZ42_022790	APZ42_028336	A0A162C899	A0A0P6CM72	Uncharacterized protein.	Core-binding factor subunit beta.	0.640
APZ42_022790	APZ42_032315	A0A162C899	A0A164M3F8	Uncharacterized protein.	Putative TGF-beta ligand Decapentaplegic protein.	0.462
APZ42_022790	APZ42_033023	A0A162C899	A0A164LGI4	Uncharacterized protein.	Putative TGF-beta ligand glass bottom boat protein.	0.500
APZ42_023256	APZ42_020282	A0A164V3I3	A0A0P5BZJ2	Putative G1/S-specific cyclin-D3; Belongs to the cyclin family.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.605
APZ42_023256	APZ42_022790	A0A164V3I3	A0A162C899	Putative G1/S-specific cyclin-D3; Belongs to the cyclin family.	Uncharacterized protein.	0.649