(29 nodes) Ion transport protein network (Daphnia magna)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

Your Input:
	APZ42_032292	Ryanodine receptor. (5136 aa)
	APZ42_032076	Ion_trans domain-containing protein. (289 aa)
	APZ42_029457	Putative Palmitoyltransferase; Belongs to the transient receptor (TC 1.A.4) family. (985 aa)
	APZ42_029181	Sodium channel protein. (255 aa)
	APZ42_028684	Transient receptor potential cation channel protein painless; Belongs to the transient receptor (TC 1.A.4) family. (947 aa)
	APZ42_027938	Voltage-dependent calcium channel type A subunit alpha-1. (1794 aa)
	APZ42_027601	Potassium voltage-gated channel protein Shal; Belongs to the potassium channel family. (131 aa)
	APZ42_021734	Transient receptor potential cation channel subfamily M member 5. (1858 aa)
	APZ42_021688	Transient receptor potential cation channel subfamily M member 5. (1545 aa)
	APZ42_013360	Transient receptor potential channel pyrexia; Belongs to the transient receptor (TC 1.A.4) family. (983 aa)
	APZ42_018926	Putative Transient receptor potential channel pyrexia; Belongs to the transient receptor (TC 1.A.4) family. (692 aa)
	APZ42_014077	Mucolipin-1. (652 aa)
	APZ42_019814	Two pore calcium channel protein 1. (830 aa)
	APZ42_021176	Putative Voltage-dependent T-type calcium channel subunit alpha-1I. (1453 aa)
	APZ42_021184	Voltage-dependent T-type calcium channel subunit alpha-1G. (168 aa)
	APZ42_026663	Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1891 aa)
	APZ42_023828	Putative Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C; Belongs to the transient receptor (TC 1.A.4) family. (1203 aa)
	APZ42_023627	Short transient receptor potential channel 6; Belongs to the transient receptor (TC 1.A.4) family. (1149 aa)
	APZ42_023425	Putative Voltage-dependent T-type calcium channel subunit alpha-1G. (791 aa)
	APZ42_016768	Cyclic-nucleotide-gated ion channel protein. (708 aa)
	APZ42_027110	Voltage-dependent calcium channel type D subunit alpha-1. (80 aa)
	APZ42_017978	Sodium channel protein. (164 aa)
	APZ42_017925	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1513 aa)
	APZ42_013404	Putative Transient receptor potential channel pyrexia; Belongs to the transient receptor (TC 1.A.4) family. (1130 aa)
	APZ42_016628	Sodium leak channel non-selective protein. (1789 aa)
	APZ42_022906	Inositol 1,4,5-trisphosphate receptor type. (2851 aa)
	APZ42_030653	Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (1446 aa)
	APZ42_033662	Putative Cyclic nucleotide-gated cation channel beta-3. (1183 aa)
	APZ42_032451	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2598 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_013360	APZ42_022906	A0A0P5VDH9	A0A0P5ZUN0	Transient receptor potential channel pyrexia; Belongs to the transient receptor (TC 1.A.4) family.	Inositol 1,4,5-trisphosphate receptor type.	0.489
APZ42_013404	APZ42_022906	A0A0P5YJK1	A0A0P5ZUN0	Putative Transient receptor potential channel pyrexia; Belongs to the transient receptor (TC 1.A.4) family.	Inositol 1,4,5-trisphosphate receptor type.	0.489
APZ42_014077	APZ42_021688	A0A0P4ZC91	A0A0P5VTI2	Mucolipin-1.	Transient receptor potential cation channel subfamily M member 5.	0.723
APZ42_014077	APZ42_021734	A0A0P4ZC91	A0A164WHX8	Mucolipin-1.	Transient receptor potential cation channel subfamily M member 5.	0.723
APZ42_014077	APZ42_023627	A0A0P4ZC91	A0A164UUR9	Mucolipin-1.	Short transient receptor potential channel 6; Belongs to the transient receptor (TC 1.A.4) family.	0.535
APZ42_014077	APZ42_029457	A0A0P4ZC91	A0A164PLK2	Mucolipin-1.	Putative Palmitoyltransferase; Belongs to the transient receptor (TC 1.A.4) family.	0.768
APZ42_014077	APZ42_030653	A0A0P4ZC91	A0A0P6CKS2	Mucolipin-1.	Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family.	0.686
APZ42_014077	APZ42_032076	A0A0P4ZC91	A0A164MB25	Mucolipin-1.	Ion_trans domain-containing protein.	0.537
APZ42_016628	APZ42_021176	A0A0P5ZGT2	A0A164X2I8	Sodium leak channel non-selective protein.	Putative Voltage-dependent T-type calcium channel subunit alpha-1I.	0.721
APZ42_016628	APZ42_021184	A0A0P5ZGT2	A0A164X2F9	Sodium leak channel non-selective protein.	Voltage-dependent T-type calcium channel subunit alpha-1G.	0.716
APZ42_016628	APZ42_023425	A0A0P5ZGT2	A0A164UYT1	Sodium leak channel non-selective protein.	Putative Voltage-dependent T-type calcium channel subunit alpha-1G.	0.721
APZ42_016628	APZ42_032292	A0A0P5ZGT2	A0A164M377	Sodium leak channel non-selective protein.	Ryanodine receptor.	0.699
APZ42_016768	APZ42_033662	A0A165A4M6	A0A164KRA4	Cyclic-nucleotide-gated ion channel protein.	Putative Cyclic nucleotide-gated cation channel beta-3.	0.974
APZ42_017925	APZ42_017978	A0A164ZG50	A0A164ZG57	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Sodium channel protein.	0.928
APZ42_017925	APZ42_021176	A0A164ZG50	A0A164X2I8	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Putative Voltage-dependent T-type calcium channel subunit alpha-1I.	0.734
APZ42_017925	APZ42_021184	A0A164ZG50	A0A164X2F9	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Voltage-dependent T-type calcium channel subunit alpha-1G.	0.761
APZ42_017925	APZ42_023425	A0A164ZG50	A0A164UYT1	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Putative Voltage-dependent T-type calcium channel subunit alpha-1G.	0.754
APZ42_017925	APZ42_029181	A0A164ZG50	A0A164PV46	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Sodium channel protein.	0.942
APZ42_017925	APZ42_032292	A0A164ZG50	A0A164M377	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Ryanodine receptor.	0.723
APZ42_017925	APZ42_032451	A0A164ZG50	A0A164LKX6	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.	0.424