(11 nodes) JAB/MPN domain network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_012978	Lys-63-specific deubiquitinase BRCC36. (246 aa)
	EOG090X08T4	COP9 signalosome complex subunit. (310 aa)
	APZ42_016582	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (274 aa)
	APZ42_015980	Pre-mRNA-processing-splicing factor 8. (2403 aa)
	APZ42_015935	AMSH protease-like protein. (402 aa)
	APZ42_013754	COP9 signalosome complex subunit 5. (341 aa)
	APZ42_027416	26S proteasome non-ATPase regulatory subunit 14. (311 aa)
	EOG090X06SH	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (345 aa)
	APZ42_029252	MPN domain-containing protein. (476 aa)
	APZ42_032694	Uncharacterized protein. (865 aa)
	APZ42_004212	26S proteasome non-ATPase regulatory subunit 7. (313 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_004212	APZ42_012978	A0A164H788	A0A162RAI6	26S proteasome non-ATPase regulatory subunit 7.	Lys-63-specific deubiquitinase BRCC36.	0.978
APZ42_004212	APZ42_013754	A0A164H788	A0A0N8D7N5	26S proteasome non-ATPase regulatory subunit 7.	COP9 signalosome complex subunit 5.	0.906
APZ42_004212	APZ42_027416	A0A164H788	A0A0N8D5M8	26S proteasome non-ATPase regulatory subunit 7.	26S proteasome non-ATPase regulatory subunit 14.	0.999
APZ42_004212	APZ42_029252	A0A164H788	A0A164PSU2	26S proteasome non-ATPase regulatory subunit 7.	MPN domain-containing protein.	0.978
APZ42_004212	APZ42_032694	A0A164H788	A0A164LSX9	26S proteasome non-ATPase regulatory subunit 7.	Uncharacterized protein.	0.986
APZ42_004212	EOG090X06SH	A0A164H788	A0A164U3Z8	26S proteasome non-ATPase regulatory subunit 7.	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.929
APZ42_004212	EOG090X08T4	A0A164H788	A0A0P6GF60	26S proteasome non-ATPase regulatory subunit 7.	COP9 signalosome complex subunit.	0.421
APZ42_012978	APZ42_004212	A0A162RAI6	A0A164H788	Lys-63-specific deubiquitinase BRCC36.	26S proteasome non-ATPase regulatory subunit 7.	0.978
APZ42_012978	EOG090X06SH	A0A162RAI6	A0A164U3Z8	Lys-63-specific deubiquitinase BRCC36.	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.879
APZ42_013754	APZ42_004212	A0A0N8D7N5	A0A164H788	COP9 signalosome complex subunit 5.	26S proteasome non-ATPase regulatory subunit 7.	0.906
APZ42_013754	APZ42_015935	A0A0N8D7N5	A0A0P5ECE0	COP9 signalosome complex subunit 5.	AMSH protease-like protein.	0.500
APZ42_013754	APZ42_015980	A0A0N8D7N5	A0A0P5R8V3	COP9 signalosome complex subunit 5.	Pre-mRNA-processing-splicing factor 8.	0.433
APZ42_013754	APZ42_016582	A0A0N8D7N5	A0A0P5STT5	COP9 signalosome complex subunit 5.	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.654
APZ42_013754	APZ42_027416	A0A0N8D7N5	A0A0N8D5M8	COP9 signalosome complex subunit 5.	26S proteasome non-ATPase regulatory subunit 14.	0.696
APZ42_013754	APZ42_029252	A0A0N8D7N5	A0A164PSU2	COP9 signalosome complex subunit 5.	MPN domain-containing protein.	0.443
APZ42_013754	APZ42_032694	A0A0N8D7N5	A0A164LSX9	COP9 signalosome complex subunit 5.	Uncharacterized protein.	0.672
APZ42_013754	EOG090X06SH	A0A0N8D7N5	A0A164U3Z8	COP9 signalosome complex subunit 5.	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.918
APZ42_013754	EOG090X08T4	A0A0N8D7N5	A0A0P6GF60	COP9 signalosome complex subunit 5.	COP9 signalosome complex subunit.	0.999
APZ42_015935	APZ42_013754	A0A0P5ECE0	A0A0N8D7N5	AMSH protease-like protein.	COP9 signalosome complex subunit 5.	0.500
APZ42_015935	APZ42_032694	A0A0P5ECE0	A0A164LSX9	AMSH protease-like protein.	Uncharacterized protein.	0.605