(34 nodes) Pentose phosphate pathway network (Daphnia magna)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Input:
	APZ42_022726	Transketolase protein 2. (603 aa)
	APZ42_014169	WD repeat-containing protein WRAP73. (420 aa)
	APZ42_016392	Glucose-6-phosphate isomerase; Belongs to the GPI family. (594 aa)
	APZ42_021677	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
	APZ42_027466	Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (320 aa)
	APZ42_013623	Deoxyribose-phosphate aldolase. (318 aa)
	APZ42_019388	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (797 aa)
	APZ42_005839	Transketolase_C domain-containing protein. (85 aa)
	APZ42_015979	Ribose-phosphate pyrophosphokinase 1. (204 aa)
	APZ42_015981	Ribose-phosphate pyrophosphokinase 1. (149 aa)
	APZ42_014911	Glucose 1,6-bisphosphate synthase; Belongs to the phosphohexose mutase family. (600 aa)
	APZ42_014694	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (470 aa)
	APZ42_002936	CUGBP ELAV family member 4. (43 aa)
	APZ42_002558	Regucalcin-like protein. (119 aa)
	APZ42_002433	PDH_E1_M domain-containing protein. (176 aa)
	APZ42_030750	Glycerate kinase. (494 aa)
	APZ42_030070	RNA-binding protein 45. (508 aa)
	APZ42_027709	Uncharacterized protein. (2868 aa)
	APZ42_027569	Bruno-3. (390 aa)
	APZ42_026150	CUGBP ELAV family member 4. (80 aa)
	APZ42_030077	Epidermal growth factor receptor kinase substrate 8 2-like protein. (829 aa)
	APZ42_023619	Ribose-5-phosphate isomerase. (275 aa)
	APZ42_025546	TE: Reverse transcriptase. (802 aa)
	APZ42_024858	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (317 aa)
	APZ42_023691	6-phosphogluconate dehydrogenase, decarboxylating. (51 aa)
	APZ42_022509	Phosphoribosyl pyrophosphate synthase-associated protein. (354 aa)
	APZ42_022909	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (522 aa)
	APZ42_022247	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (266 aa)
	APZ42_021549	CUGBP ELAV family member 4. (167 aa)
	APZ42_020647	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (319 aa)
	APZ42_018394	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (484 aa)
	APZ42_018092	Phosphoglucomutase; Belongs to the phosphohexose mutase family. (561 aa)
	APZ42_017339	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (181 aa)
	APZ42_011710	Fructose-1,6-bisphosphatase isozyme; Belongs to the FBPase class 1 family. (337 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_002433	APZ42_011710	A0A164I9I3	A0A0P5RSK7	PDH_E1_M domain-containing protein.	Fructose-1,6-bisphosphatase isozyme; Belongs to the FBPase class 1 family.	0.895
APZ42_002433	APZ42_013623	A0A164I9I3	A0A0P6E2B4	PDH_E1_M domain-containing protein.	Deoxyribose-phosphate aldolase.	0.787
APZ42_002433	APZ42_014694	A0A164I9I3	A0A162PNM4	PDH_E1_M domain-containing protein.	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	0.715
APZ42_002433	APZ42_014911	A0A164I9I3	A0A162P131	PDH_E1_M domain-containing protein.	Glucose 1,6-bisphosphate synthase; Belongs to the phosphohexose mutase family.	0.741
APZ42_002433	APZ42_015979	A0A164I9I3	A0A162NIM7	PDH_E1_M domain-containing protein.	Ribose-phosphate pyrophosphokinase 1.	0.746
APZ42_002433	APZ42_015981	A0A164I9I3	A0A162NIP0	PDH_E1_M domain-containing protein.	Ribose-phosphate pyrophosphokinase 1.	0.746
APZ42_002433	APZ42_016392	A0A164I9I3	A0A0P5UIN3	PDH_E1_M domain-containing protein.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.928
APZ42_002433	APZ42_017339	A0A164I9I3	A0A164ZTK4	PDH_E1_M domain-containing protein.	6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.	0.733
APZ42_002433	APZ42_018092	A0A164I9I3	A0A164ZBS7	PDH_E1_M domain-containing protein.	Phosphoglucomutase; Belongs to the phosphohexose mutase family.	0.798
APZ42_002433	APZ42_018394	A0A164I9I3	A0A164Z6J0	PDH_E1_M domain-containing protein.	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.	0.715
APZ42_002433	APZ42_019388	A0A164I9I3	A0A162CEM4	PDH_E1_M domain-containing protein.	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	0.761
APZ42_002433	APZ42_020647	A0A164I9I3	A0A164XAI5	PDH_E1_M domain-containing protein.	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.	0.720
APZ42_002433	APZ42_021677	A0A164I9I3	A0A0P5VU19	PDH_E1_M domain-containing protein.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.862
APZ42_002433	APZ42_022247	A0A164I9I3	A0A164W5C1	PDH_E1_M domain-containing protein.	Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.	0.887
APZ42_002433	APZ42_022509	A0A164I9I3	A0A164VLK5	PDH_E1_M domain-containing protein.	Phosphoribosyl pyrophosphate synthase-associated protein.	0.759
APZ42_002433	APZ42_022909	A0A164I9I3	A0A164VXB2	PDH_E1_M domain-containing protein.	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.	0.878
APZ42_002433	APZ42_023619	A0A164I9I3	A0A0N8AP42	PDH_E1_M domain-containing protein.	Ribose-5-phosphate isomerase.	0.877
APZ42_002433	APZ42_023691	A0A164I9I3	A0A164UPP3	PDH_E1_M domain-containing protein.	6-phosphogluconate dehydrogenase, decarboxylating.	0.647
APZ42_002433	APZ42_024858	A0A164I9I3	A0A164TMV7	PDH_E1_M domain-containing protein.	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.	0.720
APZ42_002433	APZ42_025546	A0A164I9I3	A0A164SY62	PDH_E1_M domain-containing protein.	TE: Reverse transcriptase.	0.712