(48 nodes) Alanine, aspartate and glutamate metabolism network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_024537	4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (496 aa)
	APZ42_018780	Glutamine synthetase. (366 aa)
	APZ42_018491	N-acetylated-alpha-linked acidic dipeptidase-like protein. (730 aa)
	APZ42_024153	Succinate-semialdehyde dehydrogenase, mitochondrial. (502 aa)
	APZ42_016345	Aspartate aminotransferase. (430 aa)
	APZ42_034435	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (455 aa)
	APZ42_028386	D-aspartate oxidase. (339 aa)
	APZ42_026541	4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (497 aa)
	APZ42_009341	Uncharacterized protein. (59 aa)
	APZ42_019999	Glutamate synthase. (2078 aa)
	APZ42_019312	Alanine aminotransferase 2. (325 aa)
	APZ42_014909	CAD protein. (2245 aa)
	APZ42_014954	Argininosuccinate synthase. (408 aa)
	APZ42_015043	N4-beta-N-acetylglucosaminyl-L-asparaginase. (281 aa)
	APZ42_014774	Threonine aspartase 1. (337 aa)
	APZ42_014766	Argininosuccinate lyase. (427 aa)
	APZ42_014240	NFU1 iron-sulfur cluster scaffold, mitochondrial. (230 aa)
	APZ42_013122	Serine--pyruvate aminotransferase. (392 aa)
	APZ42_012475	G patch domain and KOW motifs-containing protein. (504 aa)
	APZ42_012180	Aspartate aminotransferase. (411 aa)
	APZ42_011903	Putative N-acetylated-alpha-linked acidic dipeptidase. (782 aa)
	APZ42_011666	Asparagine synthetase domain-containing protein. (575 aa)
	APZ42_004464	Putative Retinal dehydrogenase 1. (91 aa)
	APZ42_003286	Glutamine synthetase; Belongs to the glutamine synthetase family. (238 aa)
	APZ42_003043	Uncharacterized protein. (111 aa)
	APZ42_002595	Putative Glutamate synthase. (154 aa)
	APZ42_002154	Delta-1-pyrroline-5-carboxylate dehydrogenase-like protein. (189 aa)
	APZ42_002145	Transgly domain-containing protein. (202 aa)
	APZ42_033975	L-asparaginase. (742 aa)
	APZ42_032640	N-acetylated-alpha-linked acidic dipeptidase-like protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (670 aa)
	APZ42_030973	Class B secretin G-protein-coupled receptor gproca3. (159 aa)
	APZ42_028629	Uncharacterized protein. (734 aa)
	APZ42_028165	Uncharacterized protein. (1134 aa)
	APZ42_028025	Alanine--glyoxylate aminotransferase. (226 aa)
	APZ42_025987	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (576 aa)
	APZ42_024930	Uncharacterized protein. (140 aa)
	APZ42_024920	Uncharacterized protein. (1040 aa)
	APZ42_024782	ATPase family AAA domain-containing protein 1-A; Belongs to the AAA ATPase family. (301 aa)
	APZ42_024553	4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (539 aa)
	APZ42_023746	Glutaminase kidney. (306 aa)
	APZ42_023872	Uncharacterized protein. (791 aa)
	APZ42_022792	Glutamate decarboxylase. (513 aa)
	APZ42_020541	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (530 aa)
	APZ42_020550	Adenylosuccinate lyase. (496 aa)
	APZ42_019194	Alanine--glyoxylate aminotransferase. (146 aa)
	APZ42_018993	N4-beta-N-acetylglucosaminyl-L-asparaginase. (310 aa)
	APZ42_018492	Uncharacterized protein. (456 aa)
	APZ42_016291	Glucosamine--fructose-6-phosphate aminotransferase 2. (676 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_002145	APZ42_002154	A0A164IH54	A0A164IGV6	Transgly domain-containing protein.	Delta-1-pyrroline-5-carboxylate dehydrogenase-like protein.	0.666
APZ42_002145	APZ42_002595	A0A164IH54	A0A164I660	Transgly domain-containing protein.	Putative Glutamate synthase.	0.681
APZ42_002145	APZ42_003043	A0A164IH54	A0A164HVF3	Transgly domain-containing protein.	Uncharacterized protein.	0.746
APZ42_002145	APZ42_004464	A0A164IH54	A0A164H1G0	Transgly domain-containing protein.	Putative Retinal dehydrogenase 1.	0.689
APZ42_002145	APZ42_011666	A0A164IH54	A0A162SX85	Transgly domain-containing protein.	Asparagine synthetase domain-containing protein.	0.872
APZ42_002145	APZ42_014240	A0A164IH54	A0A162Q608	Transgly domain-containing protein.	NFU1 iron-sulfur cluster scaffold, mitochondrial.	0.650
APZ42_002145	APZ42_014909	A0A164IH54	A0A162P1A7	Transgly domain-containing protein.	CAD protein.	0.767
APZ42_002145	APZ42_014954	A0A164IH54	A0A162P1R3	Transgly domain-containing protein.	Argininosuccinate synthase.	0.733
APZ42_002145	APZ42_016291	A0A164IH54	A0A165ACC9	Transgly domain-containing protein.	Glucosamine--fructose-6-phosphate aminotransferase 2.	0.746
APZ42_002145	APZ42_019194	A0A164IH54	A0A164YDY3	Transgly domain-containing protein.	Alanine--glyoxylate aminotransferase.	0.589
APZ42_002145	APZ42_019312	A0A164IH54	A0A162CFM0	Transgly domain-containing protein.	Alanine aminotransferase 2.	0.766
APZ42_002145	APZ42_019999	A0A164IH54	A0A162CE36	Transgly domain-containing protein.	Glutamate synthase.	0.681
APZ42_002145	APZ42_020541	A0A164IH54	A0A164X753	Transgly domain-containing protein.	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.863
APZ42_002145	APZ42_020550	A0A164IH54	A0A164X8B4	Transgly domain-containing protein.	Adenylosuccinate lyase.	0.434
APZ42_002145	APZ42_022792	A0A164IH54	A0A164VTD3	Transgly domain-containing protein.	Glutamate decarboxylase.	0.612
APZ42_002145	APZ42_023746	A0A164IH54	A0A164U4B0	Transgly domain-containing protein.	Glutaminase kidney.	0.861
APZ42_002145	APZ42_024153	A0A164IH54	A0A0P5EC06	Transgly domain-containing protein.	Succinate-semialdehyde dehydrogenase, mitochondrial.	0.689
APZ42_002145	APZ42_024537	A0A164IH54	A0A0N8CZN7	Transgly domain-containing protein.	4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.589
APZ42_002145	APZ42_024553	A0A164IH54	A0A164TYQ6	Transgly domain-containing protein.	4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.589
APZ42_002145	APZ42_025987	A0A164IH54	A0A164SKH1	Transgly domain-containing protein.	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.666