(74 nodes) Glycine, serine and threonine metabolism network (Daphnia magna)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	APZ42_021567	Xaa-Pro aminopeptidase 1; Belongs to the peptidase M24B family. (738 aa)
	APZ42_025887	Glucose dehydrogenase. (551 aa)
	APZ42_024494	L-allo-threonine aldolase. (389 aa)
	APZ42_022926	Dihydrolipoyl dehydrogenase. (501 aa)
	APZ42_022007	Choline dehydrogenase, mitochondrial. (633 aa)
	APZ42_021095	Neither inactivation nor afterpotential protein G. (678 aa)
	APZ42_021177	Putative Glucose dehydrogenase; Belongs to the GMC oxidoreductase family. (1042 aa)
	APZ42_003967	Putative Glycine cleavage system H protein. (49 aa)
	APZ42_030843	Serine racemase. (640 aa)
	APZ42_028589	Glucose dehydrogenase; Belongs to the GMC oxidoreductase family. (236 aa)
	APZ42_006042	Glucose dehydrogenase. (126 aa)
	APZ42_002221	Dihydrolipoamide dehydrogenase-like protein. (160 aa)
	APZ42_010544	Xaa-Pro aminopeptidase 1. (113 aa)
	APZ42_004017	Aldehyde dehydrogenase family 7 member A1. (86 aa)
	APZ42_018441	Glucose dehydrogenase. (471 aa)
	APZ42_021135	Choline dehydrogenase, mitochondrial. (650 aa)
	APZ42_003207	Oxidored_molyb domain-containing protein. (146 aa)
	APZ42_003307	Putative Cystathionine gamma-lyase. (140 aa)
	APZ42_005931	Cystathionine gamma-lyase-like protein. (147 aa)
	APZ42_030528	Meiotic recombination protein SPO11. (363 aa)
	APZ42_030079	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (404 aa)
	APZ42_024015	Glyoxylate reductase/hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (358 aa)
	APZ42_019375	Putative Xaa-Pro aminopeptidase 3. (508 aa)
	APZ42_021785	Phosphoserine aminotransferase. (362 aa)
	APZ42_018846	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (543 aa)
	APZ42_030945	Cystathionine gamma-lyase. (394 aa)
	APZ42_014230	Putative Calcium-independent phospholipase A2-gamma. (734 aa)
	APZ42_033483	Phosphoserine phosphatase. (224 aa)
	APZ42_028980	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (524 aa)
	APZ42_022182	Glycine N-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family. (288 aa)
	APZ42_022005	Glucose dehydrogenase (FAD, quinone). (620 aa)
	APZ42_014602	Threonine synthase 2. (476 aa)
	APZ42_015422	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (486 aa)
	APZ42_028234	Sarcosine dehydrogenase, mitochondrial. (904 aa)
	APZ42_018096	2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial. (431 aa)
	APZ42_028587	Glucose dehydrogenase (FAD, quinone). (619 aa)
	APZ42_010991	Xaa-Pro aminopeptidase 1; Belongs to the peptidase M24B family. (708 aa)
	APZ42_027073	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (167 aa)
	APZ42_026612	Amine oxidase. (562 aa)
	APZ42_028631	Glucose dehydrogenase (FAD, quinone). (619 aa)
	APZ42_027033	L-threonine 3-dehydrogenase, mitochondrial. (350 aa)
	APZ42_033870	5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (547 aa)
	APZ42_020646	Myotubularin-related protein 9. (566 aa)
	APZ42_019194	Alanine--glyoxylate aminotransferase. (146 aa)
	APZ42_018089	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1006 aa)
	APZ42_017393	Neither inactivation nor afterpotential protein G. (636 aa)
	APZ42_015041	Xaa-Pro aminopeptidase 1; Belongs to the peptidase M24B family. (610 aa)
	APZ42_015250	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (253 aa)
	APZ42_013661	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (468 aa)
	APZ42_013122	Serine--pyruvate aminotransferase. (392 aa)
	APZ42_012429	Glucose dehydrogenase. (623 aa)
	APZ42_011192	Putative Xaa-Pro dipeptidase. (367 aa)
	APZ42_009819	Glucose dehydrogenase. (80 aa)
	APZ42_009258	Putative Glycine dehydrogenase. (99 aa)
	APZ42_008780	Glucose dehydrogenase. (126 aa)
	APZ42_006626	Xaa-Pro aminopeptidase 1. (226 aa)
	APZ42_006041	Glucose dehydrogenase. (80 aa)
	APZ42_005974	Xaa-Pro dipeptidase. (82 aa)
	APZ42_004297	Xaa-Pro dipeptidase. (105 aa)
	APZ42_004016	Aldehyde dehydrogenase family 7 member A1. (73 aa)
	APZ42_003220	Putative Phosphoserine aminotransferase. (131 aa)
	APZ42_002258	Aspartokinase-like protein. (164 aa)
	APZ42_001985	Putative Glycine dehydrogenase. (249 aa)
	APZ42_001854	Dihydrolipoamide dehydrogenase-like protein. (117 aa)
	APZ42_030951	Eip55E. (411 aa)
	APZ42_030750	Glycerate kinase. (494 aa)
	APZ42_029642	Xaa-Pro aminopeptidase 1; Belongs to the peptidase M24B family. (844 aa)
	APZ42_028596	Glucose dehydrogenase; Belongs to the GMC oxidoreductase family. (256 aa)
	APZ42_028711	Glucose dehydrogenase. (104 aa)
	APZ42_028696	Glucose dehydrogenase. (604 aa)
	APZ42_028693	Glucose dehydrogenase; Belongs to the GMC oxidoreductase family. (728 aa)
	APZ42_028025	Alanine--glyoxylate aminotransferase. (226 aa)
	APZ42_027074	Sarcosine dehydrogenase, mitochondrial. (941 aa)
	APZ42_026943	Putative Aldehyde dehydrogenase family 7 member A1; Belongs to the aldehyde dehydrogenase family. (496 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_001854	APZ42_001985	A0A164IPI5	A0A164ILD0	Dihydrolipoamide dehydrogenase-like protein.	Putative Glycine dehydrogenase.	0.723
APZ42_001854	APZ42_002221	A0A164IPI5	A0A162CZ45	Dihydrolipoamide dehydrogenase-like protein.	Dihydrolipoamide dehydrogenase-like protein.	0.946
APZ42_001854	APZ42_003307	A0A164IPI5	A0A162C2Y4	Dihydrolipoamide dehydrogenase-like protein.	Putative Cystathionine gamma-lyase.	0.574
APZ42_001854	APZ42_003967	A0A164IPI5	A0A162F172	Dihydrolipoamide dehydrogenase-like protein.	Putative Glycine cleavage system H protein.	0.726
APZ42_001854	APZ42_004016	A0A164IPI5	A0A164HAW7	Dihydrolipoamide dehydrogenase-like protein.	Aldehyde dehydrogenase family 7 member A1.	0.536
APZ42_001854	APZ42_004017	A0A164IPI5	A0A162CVW8	Dihydrolipoamide dehydrogenase-like protein.	Aldehyde dehydrogenase family 7 member A1.	0.537
APZ42_001854	APZ42_005931	A0A164IPI5	A0A162BX80	Dihydrolipoamide dehydrogenase-like protein.	Cystathionine gamma-lyase-like protein.	0.574
APZ42_001854	APZ42_009258	A0A164IPI5	A0A164E4D4	Dihydrolipoamide dehydrogenase-like protein.	Putative Glycine dehydrogenase.	0.677
APZ42_001854	APZ42_013122	A0A164IPI5	A0A162R2B2	Dihydrolipoamide dehydrogenase-like protein.	Serine--pyruvate aminotransferase.	0.682
APZ42_001854	APZ42_013661	A0A164IPI5	A0A162QQA6	Dihydrolipoamide dehydrogenase-like protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.724
APZ42_001854	APZ42_015422	A0A164IPI5	A0A0P5KBS5	Dihydrolipoamide dehydrogenase-like protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.724
APZ42_001854	APZ42_018089	A0A164IPI5	A0A164ZBS1	Dihydrolipoamide dehydrogenase-like protein.	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.	0.723
APZ42_001854	APZ42_018096	A0A164IPI5	A0A0P5E0Y6	Dihydrolipoamide dehydrogenase-like protein.	2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial.	0.578
APZ42_001854	APZ42_018846	A0A164IPI5	A0A0P5Z299	Dihydrolipoamide dehydrogenase-like protein.	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.715
APZ42_001854	APZ42_019194	A0A164IPI5	A0A164YDY3	Dihydrolipoamide dehydrogenase-like protein.	Alanine--glyoxylate aminotransferase.	0.558
APZ42_001854	APZ42_024015	A0A164IPI5	A0A0P6CY90	Dihydrolipoamide dehydrogenase-like protein.	Glyoxylate reductase/hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.822
APZ42_001854	APZ42_024494	A0A164IPI5	A0A164TX14	Dihydrolipoamide dehydrogenase-like protein.	L-allo-threonine aldolase.	0.799
APZ42_001854	APZ42_026943	A0A164IPI5	A0A164RTP3	Dihydrolipoamide dehydrogenase-like protein.	Putative Aldehyde dehydrogenase family 7 member A1; Belongs to the aldehyde dehydrogenase family.	0.537
APZ42_001854	APZ42_027073	A0A164IPI5	A0A0P4X8M5	Dihydrolipoamide dehydrogenase-like protein.	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family.	0.726
APZ42_001854	APZ42_027074	A0A164IPI5	A0A164RRI0	Dihydrolipoamide dehydrogenase-like protein.	Sarcosine dehydrogenase, mitochondrial.	0.672