(57 nodes) Glyoxylate and dicarboxylate metabolism network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_030750	Glycerate kinase. (494 aa)
	APZ42_026191	Methylmalonyl-CoA mutase, mitochondrial. (745 aa)
	APZ42_026853	WD and tetratricopeptide repeats protein 1. (682 aa)
	APZ42_025174	Iron-responsive element binding protein 2 variant. (1065 aa)
	APZ42_022188	Protein-histidine N-methyltransferase. (498 aa)
	APZ42_027073	Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (167 aa)
	APZ42_029761	Centromere-associated protein E. (2036 aa)
	APZ42_018780	Glutamine synthetase. (366 aa)
	APZ42_026446	Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites. (302 aa)
	APZ42_014979	Protein NipSnapA. (229 aa)
	APZ42_031944	Malate dehydrogenase. (333 aa)
	APZ42_024491	Propionyl-CoA carboxylase beta chain, mitochondrial. (535 aa)
	APZ42_015422	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (486 aa)
	APZ42_012355	Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial. (716 aa)
	APZ42_022622	Acetyl-CoA acetyltransferase, cytosolic; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
	APZ42_012378	Acetyl-CoA acetyltransferase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. (501 aa)
	APZ42_014230	Putative Calcium-independent phospholipase A2-gamma. (734 aa)
	APZ42_026548	Phospholysine phosphohistidine inorganic pyrophosphate phosphatase; Belongs to the HAD-like hydrolase superfamily. (301 aa)
	APZ42_021839	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (787 aa)
	APZ42_027201	Hydroxyacid oxidase 1. (369 aa)
	APZ42_016289	Malate dehydrogenase. (340 aa)
	APZ42_024015	Glyoxylate reductase/hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (358 aa)
	APZ42_030079	Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (404 aa)
	APZ42_018401	Acetyl-coenzyme A synthetase. (652 aa)
	APZ42_008785	Catalase. (70 aa)
	APZ42_002830	Putative Beta-ketoacyl-acp reductase. (76 aa)
	APZ42_011187	VOC domain-containing protein. (156 aa)
	APZ42_017709	Citrate synthase. (199 aa)
	APZ42_002282	Uncharacterized protein. (189 aa)
	APZ42_002221	Dihydrolipoamide dehydrogenase-like protein. (160 aa)
	APZ42_005537	Uncharacterized protein. (141 aa)
	APZ42_003967	Putative Glycine cleavage system H protein. (49 aa)
	APZ42_013661	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (468 aa)
	APZ42_013392	Putative Hydroxypyruvate isomerase. (380 aa)
	APZ42_013122	Serine--pyruvate aminotransferase. (392 aa)
	APZ42_011176	SET domain-containing protein 4. (414 aa)
	APZ42_010287	Catalase. (76 aa)
	APZ42_009258	Putative Glycine dehydrogenase. (99 aa)
	APZ42_006967	Catalase. (80 aa)
	APZ42_005869	Cytoplasmic aconitate hydratase. (163 aa)
	APZ42_004166	Uncharacterized protein. (126 aa)
	APZ42_003286	Glutamine synthetase; Belongs to the glutamine synthetase family. (238 aa)
	APZ42_003256	Putative Trifunctional purine biosynthetic protein adenosine-3/sw. (68 aa)
	APZ42_003200	Putative Alcohol dehydrogenase. (117 aa)
	APZ42_002400	Putative Acetyl-Coenzyme A synthetase. (210 aa)
	APZ42_002157	METMALONYL_COA_MUTASE domain-containing protein. (173 aa)
	APZ42_002145	Transgly domain-containing protein. (202 aa)
	APZ42_001985	Putative Glycine dehydrogenase. (249 aa)
	APZ42_001854	Dihydrolipoamide dehydrogenase-like protein. (117 aa)
	APZ42_016500	N-acetylneuraminate lyase; Belongs to the DapA family. (330 aa)
	APZ42_016294	Acetyl-coenzyme A synthetase. (630 aa)
	APZ42_018089	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1006 aa)
	APZ42_020983	Uncharacterized protein. (566 aa)
	APZ42_022926	Dihydrolipoyl dehydrogenase. (501 aa)
	APZ42_024575	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (504 aa)
	APZ42_024782	ATPase family AAA domain-containing protein 1-A; Belongs to the AAA ATPase family. (301 aa)
	APZ42_029419	Protein NipSnap. (273 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_001854	APZ42_001985	A0A164IPI5	A0A164ILD0	Dihydrolipoamide dehydrogenase-like protein.	Putative Glycine dehydrogenase.	0.723
APZ42_001854	APZ42_002145	A0A164IPI5	A0A164IH54	Dihydrolipoamide dehydrogenase-like protein.	Transgly domain-containing protein.	0.667
APZ42_001854	APZ42_002221	A0A164IPI5	A0A162CZ45	Dihydrolipoamide dehydrogenase-like protein.	Dihydrolipoamide dehydrogenase-like protein.	0.946
APZ42_001854	APZ42_002400	A0A164IPI5	A0A164IAC2	Dihydrolipoamide dehydrogenase-like protein.	Putative Acetyl-Coenzyme A synthetase.	0.454
APZ42_001854	APZ42_002830	A0A164IPI5	A0A162C481	Dihydrolipoamide dehydrogenase-like protein.	Putative Beta-ketoacyl-acp reductase.	0.485
APZ42_001854	APZ42_003200	A0A164IPI5	A0A164HQU4	Dihydrolipoamide dehydrogenase-like protein.	Putative Alcohol dehydrogenase.	0.485
APZ42_001854	APZ42_003286	A0A164IPI5	A0A164HN34	Dihydrolipoamide dehydrogenase-like protein.	Glutamine synthetase; Belongs to the glutamine synthetase family.	0.719
APZ42_001854	APZ42_003967	A0A164IPI5	A0A162F172	Dihydrolipoamide dehydrogenase-like protein.	Putative Glycine cleavage system H protein.	0.726
APZ42_001854	APZ42_004166	A0A164IPI5	A0A164H876	Dihydrolipoamide dehydrogenase-like protein.	Uncharacterized protein.	0.830
APZ42_001854	APZ42_009258	A0A164IPI5	A0A164E4D4	Dihydrolipoamide dehydrogenase-like protein.	Putative Glycine dehydrogenase.	0.677
APZ42_001854	APZ42_013122	A0A164IPI5	A0A162R2B2	Dihydrolipoamide dehydrogenase-like protein.	Serine--pyruvate aminotransferase.	0.682
APZ42_001854	APZ42_013661	A0A164IPI5	A0A162QQA6	Dihydrolipoamide dehydrogenase-like protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.724
APZ42_001854	APZ42_015422	A0A164IPI5	A0A0P5KBS5	Dihydrolipoamide dehydrogenase-like protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.724
APZ42_001854	APZ42_016289	A0A164IPI5	A0A0P6AFG0	Dihydrolipoamide dehydrogenase-like protein.	Malate dehydrogenase.	0.882
APZ42_001854	APZ42_016294	A0A164IPI5	A0A165ACK3	Dihydrolipoamide dehydrogenase-like protein.	Acetyl-coenzyme A synthetase.	0.454
APZ42_001854	APZ42_017709	A0A164IPI5	A0A162CJG4	Dihydrolipoamide dehydrogenase-like protein.	Citrate synthase.	0.830
APZ42_001854	APZ42_018089	A0A164IPI5	A0A164ZBS1	Dihydrolipoamide dehydrogenase-like protein.	Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.	0.723
APZ42_001854	APZ42_018401	A0A164IPI5	A0A0P6GZT6	Dihydrolipoamide dehydrogenase-like protein.	Acetyl-coenzyme A synthetase.	0.454
APZ42_001854	APZ42_018780	A0A164IPI5	A0A0P4ZGE0	Dihydrolipoamide dehydrogenase-like protein.	Glutamine synthetase.	0.719
APZ42_001854	APZ42_020983	A0A164IPI5	A0A164WVQ8	Dihydrolipoamide dehydrogenase-like protein.	Uncharacterized protein.	0.404