(29 nodes) Butanoate metabolism network (Daphnia magna)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	APZ42_011144	Trifunctional enzyme subunit alpha. (658 aa)
	APZ42_017383	Enoyl-CoA hydratase, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family. (295 aa)
	APZ42_024153	Succinate-semialdehyde dehydrogenase, mitochondrial. (502 aa)
	APZ42_014556	D-beta-hydroxybutyrate dehydrogenase, mitochondrial. (394 aa)
	APZ42_022622	Acetyl-CoA acetyltransferase, cytosolic; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
	APZ42_012378	Acetyl-CoA acetyltransferase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family. (501 aa)
	APZ42_014558	Hydroxysteroid 11-beta-dehydrogenase 1-like protein. (386 aa)
	APZ42_014885	4-hydroxybutyrate Coenzyme A transferase. (462 aa)
	APZ42_028207	3-hydroxypropionyl-Coenzyme A dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (300 aa)
	APZ42_026541	4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (497 aa)
	APZ42_002830	Putative Beta-ketoacyl-acp reductase. (76 aa)
	APZ42_020644	3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic. (1780 aa)
	APZ42_024537	4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (496 aa)
	APZ42_007270	Hydroxymethylglutaryl-CoA synthase 1. (45 aa)
	APZ42_014660	L-2-hydroxyglutarate dehydrogenase. (245 aa)
	APZ42_005699	3-hydroxyacyl-CoA dehyrogenase-like protein. (105 aa)
	APZ42_005676	3-hydroxyacyl-CoA dehyrogenase-like protein. (186 aa)
	APZ42_004464	Putative Retinal dehydrogenase 1. (91 aa)
	APZ42_003200	Putative Alcohol dehydrogenase. (117 aa)
	APZ42_002597	Uncharacterized protein. (104 aa)
	APZ42_001998	Putative Trifunctional enzyme subunit alpha. (108 aa)
	APZ42_001925	Putative Lambda-crystallin. (169 aa)
	APZ42_029080	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (499 aa)
	APZ42_028940	Lambda-crystallin. (321 aa)
	APZ42_024553	4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (539 aa)
	APZ42_023507	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (351 aa)
	APZ42_022792	Glutamate decarboxylase. (513 aa)
	APZ42_020641	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (420 aa)
	APZ42_019662	Short-chain dehydrogenase/reductase. (313 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_001925	APZ42_002597	A0A164IMU7	A0A164I645	Putative Lambda-crystallin.	Uncharacterized protein.	0.732
APZ42_001925	APZ42_002830	A0A164IMU7	A0A162C481	Putative Lambda-crystallin.	Putative Beta-ketoacyl-acp reductase.	0.468
APZ42_001925	APZ42_003200	A0A164IMU7	A0A164HQU4	Putative Lambda-crystallin.	Putative Alcohol dehydrogenase.	0.468
APZ42_001925	APZ42_004464	A0A164IMU7	A0A164H1G0	Putative Lambda-crystallin.	Putative Retinal dehydrogenase 1.	0.490
APZ42_001925	APZ42_005676	A0A164IMU7	A0A164GBK2	Putative Lambda-crystallin.	3-hydroxyacyl-CoA dehyrogenase-like protein.	0.699
APZ42_001925	APZ42_005699	A0A164IMU7	A0A164GB08	Putative Lambda-crystallin.	3-hydroxyacyl-CoA dehyrogenase-like protein.	0.749
APZ42_001925	APZ42_007270	A0A164IMU7	A0A162D287	Putative Lambda-crystallin.	Hydroxymethylglutaryl-CoA synthase 1.	0.635
APZ42_001925	APZ42_012378	A0A164IMU7	A0A0P5XC51	Putative Lambda-crystallin.	Acetyl-CoA acetyltransferase, mitochondrial; Belongs to the thiolase-like superfamily. Thiolase family.	0.881
APZ42_001925	APZ42_014885	A0A164IMU7	A0A0P6A1S4	Putative Lambda-crystallin.	4-hydroxybutyrate Coenzyme A transferase.	0.672
APZ42_001925	APZ42_017383	A0A164IMU7	A0A0P5E7Q2	Putative Lambda-crystallin.	Enoyl-CoA hydratase, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family.	0.732
APZ42_001925	APZ42_020644	A0A164IMU7	A0A162CC70	Putative Lambda-crystallin.	3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic.	0.693
APZ42_001925	APZ42_022622	A0A164IMU7	A0A0P5X9K7	Putative Lambda-crystallin.	Acetyl-CoA acetyltransferase, cytosolic; Belongs to the thiolase-like superfamily. Thiolase family.	0.881
APZ42_001925	APZ42_023507	A0A164IMU7	A0A164UVZ8	Putative Lambda-crystallin.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.635
APZ42_001925	APZ42_024153	A0A164IMU7	A0A0P5EC06	Putative Lambda-crystallin.	Succinate-semialdehyde dehydrogenase, mitochondrial.	0.490
APZ42_001925	APZ42_024537	A0A164IMU7	A0A0N8CZN7	Putative Lambda-crystallin.	4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.557
APZ42_001925	APZ42_024553	A0A164IMU7	A0A164TYQ6	Putative Lambda-crystallin.	4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.557
APZ42_001925	APZ42_026541	A0A164IMU7	A0A0P6CX18	Putative Lambda-crystallin.	4-aminobutyrate aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.557
APZ42_001925	APZ42_028207	A0A164IMU7	A0A0P6B028	Putative Lambda-crystallin.	3-hydroxypropionyl-Coenzyme A dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.687
APZ42_001925	APZ42_028940	A0A164IMU7	A0A164Q3S9	Putative Lambda-crystallin.	Lambda-crystallin.	0.722
APZ42_001925	APZ42_029080	A0A164IMU7	A0A164PXY7	Putative Lambda-crystallin.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.747