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Fen1 Fen1 APZ42_030273 APZ42_030273 APZ42_022302 APZ42_022302 APZ42_034386 APZ42_034386 APZ42_028947 APZ42_028947 APZ42_012372 APZ42_012372 APZ42_021851 APZ42_021851 APZ42_022512 APZ42_022512 APZ42_001074 APZ42_001074 APZ42_032559 APZ42_032559 APZ42_013620 APZ42_013620 APZ42_001712 APZ42_001712 APZ42_034515 APZ42_034515 APZ42_023167 APZ42_023167 APZ42_021373 APZ42_021373 APZ42_018475 APZ42_018475 APZ42_016503 APZ42_016503
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (381 aa)
APZ42_030273Leucine-rich repeat-containing protein. (232 aa)
APZ42_022302Non-ous end-joining factor 1. (281 aa)
APZ42_034386Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (703 aa)
APZ42_028947Putative Enkurin domain-containing protein 1. (261 aa)
APZ42_012372Putative DNA cross-link repair protein pso2/snm1. (385 aa)
APZ42_021851Putative Flap endonuclease GEN. (654 aa)
APZ42_022512General transcription factor 3C polypeptide 3. (928 aa)
APZ42_001074General transcription factor 3C Polypeptide 3. (49 aa)
APZ42_032559X-ray repair cross-complementing protein 6. (251 aa)
APZ42_013620DNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family. (3687 aa)
APZ42_001712General transcription factor 3C Polypeptide 3. (108 aa)
APZ42_034515DNA repair protein RAD50; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (1342 aa)
APZ42_023167DNA ligase 4; Belongs to the ATP-dependent DNA ligase family. (891 aa)
APZ42_021373DNA repair protein RAD50. (157 aa)
APZ42_018475X-ray repair cross-complementing protein 5. (122 aa)
APZ42_016503BRCT domain-containing protein; Belongs to the DNA polymerase type-X family. (538 aa)
Your Current Organism:
Daphnia magna
NCBI taxonomy Id: 35525
Other names: D. magna
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