STRINGSTRING
APZ42_028370 APZ42_028370 APZ42_018399 APZ42_018399 APZ42_022575 APZ42_022575 APZ42_014346 APZ42_014346 APZ42_011418 APZ42_011418 APZ42_017973 APZ42_017973 APZ42_032613 APZ42_032613 APZ42_023093 APZ42_023093 APZ42_030968 APZ42_030968 APZ42_015088 APZ42_015088 APZ42_021874 APZ42_021874 APZ42_017394 APZ42_017394 APZ42_022932 APZ42_022932 APZ42_006332 APZ42_006332 APZ42_022568 APZ42_022568 APZ42_003316 APZ42_003316 APZ42_026490 APZ42_026490 APZ42_015932 APZ42_015932 APZ42_015154 APZ42_015154 APZ42_015463 APZ42_015463 APZ42_014476 APZ42_014476 APZ42_013687 APZ42_013687 APZ42_011513 APZ42_011513 APZ42_010993 APZ42_010993 APZ42_005704 APZ42_005704 APZ42_005551 APZ42_005551 APZ42_002870 APZ42_002870 APZ42_001803 APZ42_001803 APZ42_001563 APZ42_001563 APZ42_001081 APZ42_001081 APZ42_000799 APZ42_000799 APZ42_000691 APZ42_000691 APZ42_034451 APZ42_034451 APZ42_034246 APZ42_034246 APZ42_033992 APZ42_033992 APZ42_031912 APZ42_031912 APZ42_031535 APZ42_031535 APZ42_031137 APZ42_031137 APZ42_031022 APZ42_031022 APZ42_030791 APZ42_030791 APZ42_030620 APZ42_030620 APZ42_029061 APZ42_029061 APZ42_022872 APZ42_022872 APZ42_026501 APZ42_026501 APZ42_025958 APZ42_025958 APZ42_025423 APZ42_025423 APZ42_025178 APZ42_025178 APZ42_022104 APZ42_022104 APZ42_020660 APZ42_020660 APZ42_020324 APZ42_020324 APZ42_019611 APZ42_019611 APZ42_019233 APZ42_019233 APZ42_018101 APZ42_018101 APZ42_017915 APZ42_017915 APZ42_018008 APZ42_018008 APZ42_019459 APZ42_019459 EOG090X0906 EOG090X0906 APZ42_023955 APZ42_023955 APZ42_031507 APZ42_031507 APZ42_020766 APZ42_020766
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APZ42_028370Putative Fanconi anemia core complex-associated protein 24. (193 aa)
APZ42_018399WD repeat-containing protein 48. (731 aa)
APZ42_022575Methyl methanesulfonate sensitivity 4. (460 aa)
APZ42_014346Spindle assembly abnormal protein 6. (571 aa)
APZ42_011418Replication protein A 32 kDa subunit. (268 aa)
APZ42_017973Meiotic recombination protein DMC1/LIM15. (358 aa)
APZ42_032613Replication protein A 14 kDa subunit. (111 aa)
APZ42_023093Putative Fanconi anemia group A protein. (1198 aa)
APZ42_030968Ubiquitin-conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family. (301 aa)
APZ42_015088Structure-specific endonuclease subunit SLX4. (1096 aa)
APZ42_021874Nuclear transport factor 2. (128 aa)
APZ42_017394Putative Poly RNA polymerase gld-2 A. (582 aa)
APZ42_022932Regulator of telomere elongation helicase 1 homolog; ATP-dependent DNA helicase implicated in DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. (985 aa)
APZ42_006332Putative DNA helicase bloom's syndrome protein A. (251 aa)
APZ42_022568Pms2. (810 aa)
APZ42_003316DNA polymerase nu-like protein. (130 aa)
APZ42_026490ATM/Rad3 and Mei-41-like protein; Belongs to the PI3/PI4-kinase family. (2568 aa)
APZ42_015932DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (662 aa)
APZ42_015154Putative MLH1, MutL protein 1. (712 aa)
APZ42_015463Crossover junction endonuclease MUS81. (636 aa)
APZ42_014476Putative LIM domain-containing protein 2. (2301 aa)
APZ42_013687E3 ubiquitin-protein ligase FANCL. (77 aa)
APZ42_011513DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1075 aa)
APZ42_010993DNA polymerase theta. (1637 aa)
APZ42_005704DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (188 aa)
APZ42_005551Centromere protein X. (89 aa)
APZ42_002870Putative DNA excision repair protein ERCC-1. (102 aa)
APZ42_001803DNA excision repair protein ERCC-1. (120 aa)
APZ42_001563Putative E3 ubiquitin-protein ligase FANCL. (227 aa)
APZ42_001081Fanconi anemia group I protein. (226 aa)
APZ42_000799DNA repair protein REV1. (121 aa)
APZ42_000691Uncharacterized protein. (112 aa)
APZ42_034451DNA polymerase eta. (757 aa)
APZ42_034246Putative DNA helicase bloom's syndrome protein A. (1291 aa)
APZ42_033992Putative RecQ-mediated instability protein 1. (548 aa)
APZ42_031912Putative ATP-dependent RNA helicase DHX58. (1907 aa)
APZ42_031535PITH domain-containing protein 1. (207 aa)
APZ42_031137Bloom Syndrome-like protein. (639 aa)
APZ42_031022Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family. (261 aa)
APZ42_030791DNA repair Endonuclease XPF. (753 aa)
APZ42_030620Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (606 aa)
APZ42_029061Class E basic helix-loop-helix 40-like protein. (367 aa)
APZ42_022872Putative DNA polymerase IV. (555 aa)
APZ42_026501Fas apoptotic inhibitory molecule 1. (1143 aa)
APZ42_025958Putative DNA repair protein REV1. (861 aa)
APZ42_025423Fanconi anemia group I protein. (995 aa)
APZ42_025178Ubiquitin carboxyl-terminal hydrolase 1; Belongs to the peptidase C19 family. (672 aa)
APZ42_022104Putative Breast cancer type 2 susceptibility protein. (1569 aa)
APZ42_020660Uncharacterized protein. (299 aa)
APZ42_020324Putative Transcription factor HES-2. (590 aa)
APZ42_019611Putative Xeroderma pigmentosum D. (1045 aa)
APZ42_019233NEDD4-binding 2 2-like protein. (1023 aa)
APZ42_018101Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (924 aa)
APZ42_017915DNA polymerase. (1953 aa)
APZ42_018008Putative DNA polymerase iota. (528 aa)
APZ42_019459Hairy enhancer of split-like 1. (235 aa)
EOG090X0906DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (341 aa)
APZ42_023955Fanconi anemia group D2 protein. (1468 aa)
APZ42_031507Breast and ovarian cancer sususceptibility protein. (952 aa)
APZ42_020766Centromere protein S. (148 aa)
Your Current Organism:
Daphnia magna
NCBI taxonomy Id: 35525
Other names: D. magna
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