(30 nodes) Autophagy - other network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_011181	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (454 aa)
	APZ42_033416	Serine/threonine-protein kinase ULK3; Belongs to the protein kinase superfamily. (487 aa)
	APZ42_034436	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2457 aa)
	EOG090X048D	Beclin-1-like protein. (441 aa)
	APZ42_008992	Protein kinase domain-containing protein. (99 aa)
	APZ42_014482	Uncharacterized protein. (335 aa)
	APZ42_014477	Uncharacterized protein. (764 aa)
	APZ42_014549	Phosphoinositide 3-kinase regulatory subunit 4. (1359 aa)
	APZ42_011195	Regulatory-associated protein of mTOR. (911 aa)
	APZ42_020812	Ubiquitin-conjugating enzyme ATG10-like protein. (211 aa)
	APZ42_030312	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (758 aa)
	EOG090X0AKX	Autophagy-related protein 3. (318 aa)
	APZ42_014338	WD repeat domain phosphoinositide-interacting protein 2. (444 aa)
	APZ42_012857	Autophagy-related protein 101. (222 aa)
	APZ42_030693	Autophagy protein 5; Involved in autophagic vesicle formation. (71 aa)
	APZ42_019859	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. (700 aa)
	APZ42_030853	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (475 aa)
	APZ42_019724	Serine/threonine-protein phosphatase. (309 aa)
	EOG090X0BB3	Autophagy protein 5; Involved in autophagic vesicle formation. (271 aa)
	APZ42_021015	Autophagy-related protein 16-1. (378 aa)
	APZ42_026848	Serine/threonine-protein kinase ULK2. (869 aa)
	APZ42_032463	Target of rapamycin complex subunit LST8. (321 aa)
	APZ42_017964	Phosphatidylinositol 3-kinase catalytic subunit type 3. (910 aa)
	APZ42_021131	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (230 aa)
	APZ42_020991	Autophagy-related protein 16-1. (212 aa)
	APZ42_021472	Regulatory-associated protein of mTOR. (341 aa)
	APZ42_025084	Autophagy-related protein 2 A. (429 aa)
	APZ42_025083	Autophagy-related protein 2 A. (1562 aa)
	APZ42_026033	Immunoglobulin-binding protein 1. (387 aa)
	APZ42_029279	Autophagy-related 8a. (117 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_008992	APZ42_011181	A0A164EA56	A0A0P5Z0K4	Protein kinase domain-containing protein.	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	0.962
APZ42_008992	APZ42_011195	A0A164EA56	A0A162CYR5	Protein kinase domain-containing protein.	Regulatory-associated protein of mTOR.	0.739
APZ42_008992	APZ42_012857	A0A164EA56	A0A0P5ZK01	Protein kinase domain-containing protein.	Autophagy-related protein 101.	0.909
APZ42_008992	APZ42_014338	A0A164EA56	A0A0P6D3J7	Protein kinase domain-containing protein.	WD repeat domain phosphoinositide-interacting protein 2.	0.867
APZ42_008992	APZ42_014549	A0A164EA56	A0A162PQ88	Protein kinase domain-containing protein.	Phosphoinositide 3-kinase regulatory subunit 4.	0.965
APZ42_008992	APZ42_017964	A0A164EA56	A0A164ZGM4	Protein kinase domain-containing protein.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.966
APZ42_008992	APZ42_019724	A0A164EA56	A0A0P5NDB5	Protein kinase domain-containing protein.	Serine/threonine-protein phosphatase.	0.704
APZ42_008992	APZ42_019859	A0A164EA56	A0A0P5SQA0	Protein kinase domain-containing protein.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.	0.516
APZ42_008992	APZ42_020991	A0A164EA56	A0A164WWB9	Protein kinase domain-containing protein.	Autophagy-related protein 16-1.	0.773
APZ42_008992	APZ42_021015	A0A164EA56	A0A0P5CB86	Protein kinase domain-containing protein.	Autophagy-related protein 16-1.	0.773
APZ42_008992	APZ42_021131	A0A164EA56	A0A164X197	Protein kinase domain-containing protein.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.801
APZ42_008992	APZ42_021472	A0A164EA56	A0A164WMN8	Protein kinase domain-containing protein.	Regulatory-associated protein of mTOR.	0.739
APZ42_008992	APZ42_025083	A0A164EA56	A0A164TG66	Protein kinase domain-containing protein.	Autophagy-related protein 2 A.	0.907
APZ42_008992	APZ42_025084	A0A164EA56	A0A164TGA1	Protein kinase domain-containing protein.	Autophagy-related protein 2 A.	0.907
APZ42_008992	APZ42_029279	A0A164EA56	A0A164PTL5	Protein kinase domain-containing protein.	Autophagy-related 8a.	0.873
APZ42_008992	APZ42_030312	A0A164EA56	A0A0P6GFI4	Protein kinase domain-containing protein.	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	0.967
APZ42_008992	APZ42_030693	A0A164EA56	A0A164NHN9	Protein kinase domain-containing protein.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.771
APZ42_008992	APZ42_030853	A0A164EA56	A0A0P5S5Q6	Protein kinase domain-containing protein.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.801
APZ42_008992	APZ42_032463	A0A164EA56	A0A0N8CKF5	Protein kinase domain-containing protein.	Target of rapamycin complex subunit LST8.	0.712
APZ42_008992	APZ42_034436	A0A164EA56	A0A164K7C0	Protein kinase domain-containing protein.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.814