(126 nodes) Phagosome network (Daphnia magna)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42_007357	Beta-actin protein 2. (112 aa)
	APZ42_006837	Putative Cytoplasmic dynein 1 intermediate chain. (119 aa)
	APZ42_004276	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (128 aa)
	APZ42_002873	tRNA pseudouridine synthase B. (141 aa)
	APZ42_002055	Transglut_core2 domain-containing protein. (237 aa)
	APZ42_001983	Uncharacterized protein. (500 aa)
	APZ42_001548	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (55 aa)
	APZ42_000372	YccV-like domain-containing protein. (227 aa)
	APZ42_000259	Williams-Beuren Syndrome chromosomal region 16 protein. (144 aa)
	APZ42_034410	Rho family small gtp binding protein cdc42. (214 aa)
	APZ42_034432	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (836 aa)
	APZ42_033465	Cathepsin L; Belongs to the peptidase C1 family. (335 aa)
	APZ42_033391	V-type proton ATPase subunit B. (361 aa)
	APZ42_033185	Centromere protein I. (680 aa)
	APZ42_032821	Beta-actin protein 2. (374 aa)
	APZ42_032075	Fibrillar collagen NC1 domain-containing protein. (377 aa)
	APZ42_030531	Williams-Beuren Syndrome chromosomal region 16 protein. (289 aa)
	APZ42_030378	Uncharacterized protein; Belongs to the peptidase C1 family. (327 aa)
	APZ42_030409	Metal-response element-binding transcription factor. (647 aa)
	APZ42_029351	F-box domain-containing protein. (579 aa)
	APZ42_029599	Uncharacterized protein; Belongs to the CD36 family. (484 aa)
	APZ42_029278	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (385 aa)
	APZ42_029154	Translation initiation factor IF-2. (742 aa)
	APZ42_029059	Sperm-specific dynein intermediate chain 1. (634 aa)
	APZ42_028562	V-type proton ATPase subunit S1. (447 aa)
	APZ42_011560	Dynein intermediate chain 1, axonemal. (773 aa)
	APZ42_013391	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (348 aa)
	EOG090X0RAK	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (100 aa)
	APZ42_014241	Uncharacterized protein. (1288 aa)
	APZ42_015339	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
	APZ42_014363	Integrin beta; Belongs to the integrin beta chain family. (614 aa)
	APZ42_023741	Thrombospondin. (1191 aa)
	APZ42_031672	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (413 aa)
	APZ42_001912	Fibulin 1 and. (222 aa)
	APZ42_019435	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (479 aa)
	APZ42_019811	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (699 aa)
	APZ42_022892	Uncharacterized protein. (282 aa)
	APZ42_019517	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (499 aa)
	APZ42_026093	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
	APZ42_015430	Soldier-specific protein-1. (262 aa)
	APZ42_020149	Calreticulin. (409 aa)
	APZ42_027374	V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (84 aa)
	APZ42_014287	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
	APZ42_034376	V-type proton ATPase 21 kDa proteolipid subunit; Belongs to the V-ATPase proteolipid subunit family. (209 aa)
	EOG090X0BCY	Transcription factor. (659 aa)
	APZ42_019657	Alkylated DNA repair protein alkB. (288 aa)
	APZ42_013694	t-SNARE domain-containing protein; Belongs to the syntaxin family. (278 aa)
	APZ42_021841	Ras-related protein Rab-7a. (208 aa)
	APZ42_015818	Putative Fibulin 1 and. (278 aa)
	APZ42_029349	F-box only protein 21. (532 aa)
	APZ42_022107	Putative SH3 domain-containing RING finger protein 3. (805 aa)
	APZ42_031766	Coronin; Belongs to the WD repeat coronin family. (653 aa)
	APZ42_032450	Glucosyl/glucuronosyl transferases; Belongs to the CD36 family. (542 aa)
	APZ42_030255	Integrin beta; Belongs to the integrin beta chain family. (791 aa)
	APZ42_032865	Integrin beta; Belongs to the integrin beta chain family. (810 aa)
	APZ42_033294	Putative Ras-related protein RabJ. (218 aa)
	APZ42_019868	Syntaxin-12; Belongs to the syntaxin family. (270 aa)
	APZ42_013189	Dynein intermediate chain 3, ciliary. (649 aa)
	EOG090X0F8Y	V-type proton ATPase subunit E 1. (226 aa)
	APZ42_018003	Testis development protein nyd-sp29. (652 aa)
	APZ42_023963	Cathepsin-l cysteine peptidase; Belongs to the peptidase C1 family. (330 aa)
	APZ42_023974	Cathepsin l protein; Belongs to the peptidase C1 family. (332 aa)
	EOG090X0MSH	Mitochondrial import inner membrane translocase subunit Tim9. (91 aa)
	APZ42_023908	Poly [ADP-ribose] polymerase. (1239 aa)
	APZ42_011542	Cathepsin-l cysteine peptidase; Belongs to the peptidase C1 family. (335 aa)
	APZ42_015820	Syntaxin-18. (316 aa)
	EOG090X0HBC	EOG090X0HBC; Belongs to the synaptobrevin family. (213 aa)
	APZ42_013221	Putative ATP-dependent RNA helicase DDX28. (540 aa)
	APZ42_023954	Putative Dipeptidyl peptidase 1; Belongs to the peptidase C1 family. (332 aa)
	EOG090X03O4	Transport protein Sec61 subunit alpha 1. (476 aa)
	APZ42_011302	Ras-related protein Rab-23. (251 aa)
	APZ42_026236	Ras-related C3 botulinum toxin substrate. (192 aa)
	APZ42_014290	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
	APZ42_020505	RILP protein 1. (400 aa)
	APZ42_032457	Glucosyl/glucuronosyl transferases; Belongs to the CD36 family. (484 aa)
	APZ42_014495	Ras GTP-binding protein RhoL. (184 aa)
	APZ42_029275	V-type proton ATPase catalytic subunit A. (621 aa)
	APZ42_016801	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
	APZ42_022446	Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
	APZ42_016358	Coronin; Belongs to the WD repeat coronin family. (654 aa)
	APZ42_011328	Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
	APZ42_019824	Integrator complex subunit. (332 aa)
	APZ42_028036	ATP-dependent RNA helicase DDX47; Belongs to the DEAD box helicase family. (458 aa)
	APZ42_029600	Class b scavenger receptor cd36 domain; Belongs to the CD36 family. (482 aa)
	APZ42_029884	Coronin; Belongs to the WD repeat coronin family. (552 aa)
	APZ42_014491	Ras GTP-binding protein RhoL. (187 aa)
	APZ42_024778	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (117 aa)
	APZ42_028759	Putative Complement C1q tumor necrosis factor-related protein 2. (350 aa)
	APZ42_028157	Calnexin. (588 aa)
	APZ42_027708	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (160 aa)
	APZ42_027162	1-phosphatidylinositol 3-phosphate 5-kinase. (1907 aa)
	APZ42_027315	Mitochondrial import inner membrane translocase subunit Tim9. (119 aa)
	APZ42_027342	Putative F-box only protein. (670 aa)
	APZ42_025923	Putative Lysosome-associated membrane glycoprotein 1. (344 aa)
	APZ42_025922	Scavenger receptor class B member 1; Belongs to the CD36 family. (469 aa)
	APZ42_024503	Ras-related C3 botulinum toxin substrate. (195 aa)
	APZ42_023968	Crammer; Belongs to the peptidase C1 family. (335 aa)
	APZ42_024107	Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (532 aa)
	APZ42_024156	Uncharacterized protein. (273 aa)
	APZ42_024197	Ras-related protein Rab-5C. (227 aa)
	APZ42_023681	Nitric oxide synthase; Produces nitric oxide (NO). (1262 aa)
	APZ42_023355	Nitric oxide synthase. (112 aa)
	APZ42_022275	Dynein heavy chain, cytoplasmic. (4656 aa)
	APZ42_022510	Hepatocyte growth factor-regulated tyrosine kinase substrate. (706 aa)
	APZ42_022789	Uncharacterized protein; Belongs to the peptidase C1 family. (349 aa)
	APZ42_022057	Nitric oxide synthase; Produces nitric oxide (NO). (1157 aa)
	APZ42_021393	Putative Calmodulin-binding transcription activator 1. (1335 aa)
	APZ42_020544	Putative Latent-transforming growth factor beta-binding protein 3. (9549 aa)
	APZ42_020786	Cytoplasmatic actin. (376 aa)
	APZ42_019725	Putative Sorbin and SH3 domain-containing protein. (969 aa)
	APZ42_020029	C1q domain-containing protein. (481 aa)
	APZ42_020153	V-type proton ATPase subunit D 1. (202 aa)
	APZ42_020164	V-type proton ATPase subunit D. (244 aa)
	APZ42_020220	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (122 aa)
	APZ42_019400	Uncharacterized protein. (2993 aa)
	APZ42_019515	Cytoplasmatic actin; Belongs to the actin family. (355 aa)
	APZ42_019032	Uncharacterized protein. (1094 aa)
	APZ42_019007	Tubulin alpha-1 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (440 aa)
	APZ42_018760	Uncharacterized protein. (1687 aa)
	APZ42_018949	Integrin beta; Belongs to the integrin beta chain family. (786 aa)
	APZ42_018310	Fibulin 1 and. (1433 aa)
	APZ42_017964	Phosphatidylinositol 3-kinase catalytic subunit type 3. (910 aa)
	APZ42_016942	Beta-actin protein 2. (188 aa)
	APZ42_011592	Uncharacterized protein. (195 aa)
	APZ42_011668	Cytoplasmic dynein 2 heavy chain 1. (2801 aa)
	APZ42_011677	Cytoplasmic dynein 2 heavy chain 1. (1293 aa)

Your Current Organism:

Daphnia magna

NCBI taxonomy Id: 35525
Other names: D. magna

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42_000259	APZ42_014491	A0A164JSZ9	A0A0P4XH59	Williams-Beuren Syndrome chromosomal region 16 protein.	Ras GTP-binding protein RhoL.	0.488
APZ42_000259	APZ42_014495	A0A164JSZ9	A0A0P5EG34	Williams-Beuren Syndrome chromosomal region 16 protein.	Ras GTP-binding protein RhoL.	0.488
APZ42_000259	APZ42_017964	A0A164JSZ9	A0A164ZGM4	Williams-Beuren Syndrome chromosomal region 16 protein.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.519
APZ42_000259	APZ42_024197	A0A164JSZ9	A0A164UJQ4	Williams-Beuren Syndrome chromosomal region 16 protein.	Ras-related protein Rab-5C.	0.610
APZ42_000259	APZ42_024503	A0A164JSZ9	A0A164TX58	Williams-Beuren Syndrome chromosomal region 16 protein.	Ras-related C3 botulinum toxin substrate.	0.488
APZ42_000259	APZ42_026236	A0A164JSZ9	A0A0P5IN29	Williams-Beuren Syndrome chromosomal region 16 protein.	Ras-related C3 botulinum toxin substrate.	0.488
APZ42_000259	APZ42_028157	A0A164JSZ9	A0A164QKC8	Williams-Beuren Syndrome chromosomal region 16 protein.	Calnexin.	0.528
APZ42_000259	APZ42_030531	A0A164JSZ9	A0A164NKP8	Williams-Beuren Syndrome chromosomal region 16 protein.	Williams-Beuren Syndrome chromosomal region 16 protein.	0.493
APZ42_000259	APZ42_033294	A0A164JSZ9	A0A0P5VJY2	Williams-Beuren Syndrome chromosomal region 16 protein.	Putative Ras-related protein RabJ.	0.610
APZ42_000259	APZ42_034410	A0A164JSZ9	A0A164K509	Williams-Beuren Syndrome chromosomal region 16 protein.	Rho family small gtp binding protein cdc42.	0.488
APZ42_001548	APZ42_013391	A0A164IWM1	A0A162QZL3	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	0.996
APZ42_001548	APZ42_019435	A0A164IWM1	A0A162CNC8	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	0.983
APZ42_001548	APZ42_019517	A0A164IWM1	A0A0P6IW21	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.959
APZ42_001548	APZ42_019657	A0A164IWM1	A0A0P5ZDB6	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Alkylated DNA repair protein alkB.	0.895
APZ42_001548	APZ42_019868	A0A164IWM1	A0A0P5VIF7	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Syntaxin-12; Belongs to the syntaxin family.	0.433
APZ42_001548	APZ42_020153	A0A164IWM1	A0A164Y1P1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit D 1.	0.895
APZ42_001548	APZ42_020164	A0A164IWM1	A0A164Y1Q7	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit D.	0.895
APZ42_001548	APZ42_020220	A0A164IWM1	A0A164Y3M2	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.989
APZ42_001548	APZ42_024197	A0A164IWM1	A0A164UJQ4	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	Ras-related protein Rab-5C.	0.483
APZ42_001548	APZ42_024778	A0A164IWM1	A0A0N8D104	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.972