(12 nodes) Cysteine and methionine metabolism network (Acholeplasma oculi)

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Your Input:
	dcm	C-5 cytosine specific DNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (408 aa)
	Aocu_01640	C-5 cytosine methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (353 aa)
	ldh	L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (315 aa)
	Aocu_02960	GAF domain-containing protein. (154 aa)
	ilvE	Branched-chain amino acid aminotransferase. (328 aa)
	mtnN	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (209 aa)
	sdaA	L-serine dehydratase. (403 aa)
	metK1	S-Adenosylmethionine synthetase; Belongs to the AdoMet synthase family. (371 aa)
	asd	Aspartate-semialdehyde dehydrogenase, beta-type; Belongs to the aspartate-semialdehyde dehydrogenase family. (330 aa)
	thrA	Aspartate kinase, monofunctional class; Belongs to the aspartokinase family. (400 aa)
	metK2	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (386 aa)
	nifS	Pyridoxal phosphate-dependent transferase. (396 aa)

Your Current Organism:

Acholeplasma oculi

NCBI taxonomy Id: 35623
Other names: A. oculi, ATCC 27350, Acholeplasma oculusi, NCTC 10150

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Aocu_01640	dcm	Aocu_01640	Aocu_01360	C-5 cytosine methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	C-5 cytosine specific DNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.941
Aocu_01640	metK1	Aocu_01640	Aocu_08700	C-5 cytosine methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	S-Adenosylmethionine synthetase; Belongs to the AdoMet synthase family.	0.912
Aocu_01640	metK2	Aocu_01640	Aocu_11100	C-5 cytosine methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.912
Aocu_01640	mtnN	Aocu_01640	Aocu_03450	C-5 cytosine methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.	0.901
Aocu_02960	metK1	Aocu_02960	Aocu_08700	GAF domain-containing protein.	S-Adenosylmethionine synthetase; Belongs to the AdoMet synthase family.	0.900
Aocu_02960	metK2	Aocu_02960	Aocu_11100	GAF domain-containing protein.	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.900
asd	ilvE	Aocu_08980	Aocu_03400	Aspartate-semialdehyde dehydrogenase, beta-type; Belongs to the aspartate-semialdehyde dehydrogenase family.	Branched-chain amino acid aminotransferase.	0.488
asd	thrA	Aocu_08980	Aocu_09000	Aspartate-semialdehyde dehydrogenase, beta-type; Belongs to the aspartate-semialdehyde dehydrogenase family.	Aspartate kinase, monofunctional class; Belongs to the aspartokinase family.	0.996
dcm	Aocu_01640	Aocu_01360	Aocu_01640	C-5 cytosine specific DNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	C-5 cytosine methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.941
dcm	metK1	Aocu_01360	Aocu_08700	C-5 cytosine specific DNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	S-Adenosylmethionine synthetase; Belongs to the AdoMet synthase family.	0.912
dcm	metK2	Aocu_01360	Aocu_11100	C-5 cytosine specific DNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.912
dcm	mtnN	Aocu_01360	Aocu_03450	C-5 cytosine specific DNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.	0.901
ilvE	asd	Aocu_03400	Aocu_08980	Branched-chain amino acid aminotransferase.	Aspartate-semialdehyde dehydrogenase, beta-type; Belongs to the aspartate-semialdehyde dehydrogenase family.	0.488
ilvE	ldh	Aocu_03400	Aocu_02230	Branched-chain amino acid aminotransferase.	L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.	0.852
ldh	ilvE	Aocu_02230	Aocu_03400	L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.	Branched-chain amino acid aminotransferase.	0.852
ldh	nifS	Aocu_02230	Aocu_14290	L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.	Pyridoxal phosphate-dependent transferase.	0.934
metK1	Aocu_01640	Aocu_08700	Aocu_01640	S-Adenosylmethionine synthetase; Belongs to the AdoMet synthase family.	C-5 cytosine methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.912
metK1	Aocu_02960	Aocu_08700	Aocu_02960	S-Adenosylmethionine synthetase; Belongs to the AdoMet synthase family.	GAF domain-containing protein.	0.900
metK1	dcm	Aocu_08700	Aocu_01360	S-Adenosylmethionine synthetase; Belongs to the AdoMet synthase family.	C-5 cytosine specific DNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.912
metK1	metK2	Aocu_08700	Aocu_11100	S-Adenosylmethionine synthetase; Belongs to the AdoMet synthase family.	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.908