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| | hprT | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (179 aa) |
| | fau | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (173 aa) |
| | pgi | Glucose-6-phosphate isomerase; Belongs to the GPI family. (423 aa) |
| | glnS | Glutaminyl-tRNA synthetase. (545 aa) |
| | Aocu_00710 | Terpenoid synthase; Belongs to the FPP/GGPP synthase family. (284 aa) |
| | trpB | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (391 aa) |
| | ldcC | Lysine decarboxylase. (491 aa) |
| | speB | Putative agmatinase; Belongs to the arginase family. (291 aa) |
| | pdhA | Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit subgroup x; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (361 aa) |
| | pdhB | Pyruvate dehydrogenase (acetyl-transferring) E1 component, beta subunit. (327 aa) |
| | aceF | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (538 aa) |
| | lpd | Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex. (458 aa) |
| | lplA1 | Lipoate-protein ligase A. (305 aa) |
| | nrdD | Ribonucleoside-triphosphate reductase, anaerobic. (762 aa) |
| | nrdE | Ribonucleotide reductase class Ib (aerobic), alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (700 aa) |
| | nrdF | Ribonucleotide reductase class Ib (aerobic), beta subunit. (367 aa) |
| | Aocu_01140 | Chitinase II. (648 aa) |
| | dcm | C-5 cytosine specific DNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (408 aa) |
| | Aocu_01420 | Glycosyl hydrolase, family 32; Belongs to the glycosyl hydrolase 32 family. (467 aa) |
| | xylB | Xylulose kinase. (486 aa) |
| | Aocu_01560 | Glycoside hydrolase, family 32; Belongs to the glycosyl hydrolase 32 family. (506 aa) |
| | Aocu_01640 | C-5 cytosine methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (353 aa) |
| | pheA | Prephenate dehydratase. (269 aa) |
| | ldh | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (315 aa) |
| | Aocu_02430 | Glyoxalase/bleomycin resistance protein/Dihydroxybiphenyl dioxygenase. (122 aa) |
| | Aocu_02520 | Tocopherol cyclase. (319 aa) |
| | ctrI | Phytoene desaturase. (495 aa) |
| | sufS | Iron-sulfur cluster assembly SUF system, Cysteine desulfurase SufS. (400 aa) |
| | Aocu_02850 | Putative MurD-like peptide ligase. (477 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (399 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (254 aa) |
| | thiI | tRNA sulfurtransferase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (410 aa) |
| | Aocu_03000 | Glycosyl hydrolase family 20 protein. (619 aa) |
| | Aocu_03110 | Sphingosine kinase. (280 aa) |
| | gapA | NAD-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (337 aa) |
| | ntpC1 | V-type ATP synthase subunit C. (342 aa) |
| | ntpI1 | V-type ATP synthase subunit I; Belongs to the V-ATPase 116 kDa subunit family. (640 aa) |
| | ntpK1 | V-type ATP synthase subunit K. (150 aa) |
| | ntpA1 | V-type ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (581 aa) |
| | ntpB1 | V-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. (479 aa) |
| | ntpD1 | V-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (200 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (146 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (237 aa) |
| | ilvE | Branched-chain amino acid aminotransferase. (328 aa) |
| | cdsA | Phosphatidate cytidylyltransferase; Belongs to the CDS family. (319 aa) |
| | udk | Uridine kinase. (208 aa) |
| | mtnN | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (209 aa) |
| | ppx | Exopolyphosphatase. (296 aa) |
| | alkH | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (432 aa) |
| | Aocu_03660 | Kinase, PfkB-family; Belongs to the carbohydrate kinase PfkB family. (306 aa) |
| | ald | Alanine dehydrogenase. (368 aa) |
| | Aocu_03900 | Cellobiose phosphorylase. (806 aa) |
| | Aocu_03910 | Predicted O-antigen ligase like membrane protein. (473 aa) |
| | gdhA | NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (444 aa) |
| | fabH1 | 3-oxoacyl-(acyl carrier protein) synthase. (310 aa) |
| | pfkA1 | 6-Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (414 aa) |
| | pfkA2 | 6-Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (316 aa) |
| | pykF | Pyruvate kinase; Belongs to the pyruvate kinase family. (450 aa) |
| | glnA | Glutamine synthetase type I. (443 aa) |
| | galE | UDP-glucose 4-epimerase GalE; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (331 aa) |
| | glf1 | UDP-galactopyranose mutase. (369 aa) |
| | glmS | Glucosamine-fructose-6-phosphate aminotransferase, isomerizing. (593 aa) |
| | glmM | Phosphoglucosamine mutase. (435 aa) |
| | glmU | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (460 aa) |
| | gmhA | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. (194 aa) |
| | gmhB | D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase; Belongs to the gmhB family. (166 aa) |
| | glf2 | UDP-galactopyranose mutase. (370 aa) |
| | ntpI2 | V-type ATP synthase subunit I; Belongs to the V-ATPase 116 kDa subunit family. (629 aa) |
| | ntpK2 | V-type ATP synthase subunit K; Belongs to the V-ATPase proteolipid subunit family. (163 aa) |
| | ntpE2 | V-type ATP synthase subunit E. (201 aa) |
| | ntpC2 | V-type ATP synthase subunit C. (310 aa) |
| | ntpA2 | V-type ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (586 aa) |
| | ntpB2 | V-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. (459 aa) |
| | ntpD2 | V-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (216 aa) |
| | gndA | 6-phosphogluconate dehydrogenase, decarboxylating. (299 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (447 aa) |
| | Aocu_05190 | Metallo-beta-lactamase superfamily protein. (206 aa) |
| | cdd | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (130 aa) |
| | Aocu_05480 | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase superfamily protein. (134 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (266 aa) |
| | Aocu_05540 | Phosphotransferase system, IIA component fructose subfamily. (149 aa) |
| | sdaA | L-serine dehydratase. (403 aa) |
| | Aocu_05710 | Glycoside hydrolase, family 5; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (334 aa) |
| | accE | Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (148 aa) |
| | accG | Biotin carboxylase of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (459 aa) |
| | accD | Acetyl-coenzyme A carboxyl transferase, beta chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (293 aa) |
| | accA | Acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (270 aa) |
| | fabH2 | 3-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (310 aa) |
| | fabI | Enoyl-[acyl-carrier-protein] reductase. (310 aa) |
| | fabD | Malonyl CoA-acyl carrier protein transacylase. (307 aa) |
| | fabG1 | 3-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa) |
| | fabF | 3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (413 aa) |
| | fabA | (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase. (142 aa) |
| | birA | Biotin-[acetyl-CoA-carboxylase] ligase. (171 aa) |
| | purB | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (432 aa) |
| | lafA | Glycosyltransferase LafA. (401 aa) |
| | pncB | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (478 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (394 aa) |
| | fadI | 3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa) |
| | fabG2 | 3-oxoacyl-[acyl-carrier-protein] reductase. (240 aa) |
| | fabH3 | 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III. (344 aa) |
| | Aocu_06500 | Acetyl-CoA hydrolase. (437 aa) |
| | malP | Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (791 aa) |
| | glgB | Glycogen (1,4-alpha-glucan) branching enzyme. (615 aa) |
| | malS | Alpha amylase; Belongs to the glycosyl hydrolase 13 family. (658 aa) |
| | glk | Glucose kinase. (293 aa) |
| | lafB | Glycosyltransferase LafB. (332 aa) |
| | folC | Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. (411 aa) |
| | Aocu_06820 | Alpha/beta hydrolase. (260 aa) |
| | plsY | Glycerol-3-phosphate acyltransferase PlsY; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (227 aa) |
| | lplA2 | Lipoate-protein ligase A. (330 aa) |
| | Aocu_06950 | Predicted lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis. (255 aa) |
| | Aocu_06960 | Cytidylyltransferase; Belongs to the NadD family. (187 aa) |
| | nadE | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (616 aa) |
| | malQ | Putative 4-alpha-glucanotransferase. (489 aa) |
| | malL | Putative oligo-1,6-glucosidase. (562 aa) |
| | nplT | Putative Neopullulanase. (598 aa) |
| | Aocu_07300 | Alpha-amylase. (427 aa) |
| | pulA | Pullulanase, type I; Belongs to the glycosyl hydrolase 13 family. (988 aa) |
| | Aocu_07370 | Alpha amylase. (514 aa) |
| | Aocu_07410 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (171 aa) |
| | glgA | Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (473 aa) |
| | glgC | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (408 aa) |
| | hemN | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (363 aa) |
| | deoB | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (397 aa) |
| | ansA | L-Asparaginase. (326 aa) |
| | deoA | Pyrimidine-nucleoside phosphorylase. (432 aa) |
| | plsC | 1-Acyl-sn-glycerol-3-phosphate acyltransferase. (261 aa) |
| | folA | Dihydrofolate reductase. (154 aa) |
| | thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (288 aa) |
| | pepV | Dipeptidase PepV. (458 aa) |
| | deoD | Purine nucleoside phosphorylase. (236 aa) |
| | deoC | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (222 aa) |
| | surE | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (245 aa) |
| | gph | Phosphoglycolate phosphatase. (218 aa) |
| | Aocu_07840 | Glycoside hydrolase family 3 protein. (615 aa) |
| | Aocu_07950 | Glycosyl hydrolase, family 30; Belongs to the glycosyl hydrolase 30 family. (480 aa) |
| | Aocu_07980 | Glycoside hydrolase, family 65. (833 aa) |
| | bglX | Beta-glucosidase. (1025 aa) |
| | asnB | Asparagine synthetase (glutamine-hydrolyzing). (524 aa) |
| | Aocu_08240 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (160 aa) |
| | metK1 | S-Adenosylmethionine synthetase; Belongs to the AdoMet synthase family. (371 aa) |
| | dapH | 2,3,4,5-Tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (236 aa) |
| | dapB | 4-Hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (241 aa) |
| | dapA | 4-Hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (289 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase, beta-type; Belongs to the aspartate-semialdehyde dehydrogenase family. (330 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (260 aa) |
| | thrA | Aspartate kinase, monofunctional class; Belongs to the aspartokinase family. (400 aa) |
| | lysA | Diaminopimelate decarboxylase LysA; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (418 aa) |
| | Aocu_09020 | 5'-Nucleotidase; Belongs to the 5'-nucleotidase family. (572 aa) |
| | guaC | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. (325 aa) |
| | Aocu_09050 | Acyl-ACP thioesterase. (237 aa) |
| | fni | Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (324 aa) |
| | mvaK | Phosphomevalonate kinase. (347 aa) |
| | mvaD | Diphosphomevalonate decarboxylase. (315 aa) |
| | mvk | Mevalonate kinase. (313 aa) |
| | psuG | Pseudouridine 5'-phosphate glycosidase; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (304 aa) |
| | ribF | Riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. (300 aa) |
| | comEB | dCMP deaminase. (158 aa) |
| | relA | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (723 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (170 aa) |
| | galU | UTP--glucose-1-phosphate uridylyltransferase. (286 aa) |
| | pgm | Phosphoglucomutase. (543 aa) |
| | coaX | Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (246 aa) |
| | Aocu_09570 | Beta-lactamase-like protein. (207 aa) |
| | rdgB | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (200 aa) |
| | cmk | Cytidylate kinase. (221 aa) |
| | aroQ | 3-Dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (142 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (163 aa) |
| | miaA | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (280 aa) |
| | pgsA | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (195 aa) |
| | mgsA | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (122 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (431 aa) |
| | gpmI | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (510 aa) |
| | gcvT | Glycine cleavage system T protein. (356 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (122 aa) |
| | gcvP1 | Glycine cleavage system P protein, subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (437 aa) |
| | gcvP2 | Glycine cleavage system P protein, subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (481 aa) |
| | Aocu_10550 | Phosphoribulokinase/uridine kinase family protein. (290 aa) |
| | metK2 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (386 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (159 aa) |
| | galM1 | Aldose 1-epimerase. (301 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (205 aa) |
| | kduD | 2-deoxy-D-gluconate 3-dehydrogenase. (257 aa) |
| | kduI | 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family. (278 aa) |
| | Aocu_11520 | Kinase, PfkB family. (340 aa) |
| | kdgK | Putative 2-dehydro-3-deoxygluconokinase. (326 aa) |
| | eda | 4-Hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxyphosphogluconate aldolase. (213 aa) |
| | Aocu_11640 | Pectin lyase. (294 aa) |
| | Aocu_11680 | Pectin lyase. (1297 aa) |
| | galM2 | Aldose 1-epimerase. (319 aa) |
| | nagB | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (240 aa) |
| | murQ | N-acetylmuramic acid 6-phosphate etherase MurQ; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (301 aa) |
| | nagZ | Beta-hexosaminidase. (524 aa) |
| | Aocu_12000 | FAD-linked oxidase. (465 aa) |
| | thiN | Thiamin pyrophosphokinase. (200 aa) |
| | rpe | Ribulose-5-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (210 aa) |
| | rsgA | Putative ribosome biogenesis GTPase RsgA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (317 aa) |
| | adhE2 | Bifunctional aldehyde/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (862 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (77 aa) |
| | pgl | 6-phosphogluconolactonase. (307 aa) |
| | plsX | Phosphate acyltransferase PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (334 aa) |
| | hmgS | Hydroxymethylglutaryl-CoA synthase. (381 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (328 aa) |
| | aroD | Shikimate 5-dehydrogenase I alpha. (259 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (413 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (332 aa) |
| | tyrA | Prephenate dehydrogenase. (276 aa) |
| | aroF | 3-deoxy-7-phosphoheptulonate synthase. (340 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (208 aa) |
| | rpiB | Ribose 5-phosphate isomerase B. (148 aa) |
| | Aocu_12930 | Glyoxalase/fosfomycin resistance/dioxygenase domain-containing protein. (280 aa) |
| | gltX | Glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (449 aa) |
| | metG | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. (516 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (201 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (217 aa) |
| | garR | 2-hydroxy-3-oxopropionate reductase. (287 aa) |
| | tkt | Transketolase; Belongs to the transketolase family. (651 aa) |
| | tdk | Thymidine kinase. (196 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (411 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (278 aa) |
| | fhs | Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (528 aa) |
| | pdlB | Pyruvate formate-lyase. (756 aa) |
| | cls | Cardiolipin synthetase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. (501 aa) |
| | nifS | Pyridoxal phosphate-dependent transferase. (396 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (410 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (322 aa) |
| | pduL | Similar to propanediol utilisation protein PduL; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (196 aa) |
| | fba | Fructose-1,6-bisphosphate aldolase, class II. (287 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (538 aa) |
| | Aocu_14550 | Phosphoesterase. (313 aa) |
