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pgi pgi pdhA pdhA pdhB pdhB aceF aceF lpd lpd ldh ldh pgk pgk tpiA tpiA gapA gapA alkH alkH gdhA gdhA pfkA1 pfkA1 pfkA2 pfkA2 pykF pykF glnA glnA gndA gndA zwf zwf Aocu_05540 Aocu_05540 accE accE accG accG accD accD accA accA ackA ackA fadI fadI glk glk pepV pepV dapB dapB dapA dapA asd asd dapF dapF thrA thrA lysA lysA pgm pgm mgsA mgsA eno eno gpmI gpmI galM1 galM1 Aocu_11520 Aocu_11520 kdgK kdgK eda eda galM2 galM2 Aocu_12000 Aocu_12000 rpe rpe adhE2 adhE2 pgl pgl rpiB rpiB Aocu_12930 Aocu_12930 tkt tkt glyA glyA folD folD fhs fhs pdlB pdlB prs prs pduL pduL fba fba Aocu_14550 Aocu_14550
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (423 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit subgroup x; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (361 aa)
pdhBPyruvate dehydrogenase (acetyl-transferring) E1 component, beta subunit. (327 aa)
aceFDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (538 aa)
lpdDihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex. (458 aa)
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (315 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (399 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (254 aa)
gapANAD-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (337 aa)
alkHAldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (432 aa)
gdhANADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (444 aa)
pfkA16-Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (414 aa)
pfkA26-Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (316 aa)
pykFPyruvate kinase; Belongs to the pyruvate kinase family. (450 aa)
glnAGlutamine synthetase type I. (443 aa)
gndA6-phosphogluconate dehydrogenase, decarboxylating. (299 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (447 aa)
Aocu_05540Phosphotransferase system, IIA component fructose subfamily. (149 aa)
accEBiotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (148 aa)
accGBiotin carboxylase of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (459 aa)
accDAcetyl-coenzyme A carboxyl transferase, beta chain; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (293 aa)
accAAcetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (270 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (394 aa)
fadI3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
glkGlucose kinase. (293 aa)
pepVDipeptidase PepV. (458 aa)
dapB4-Hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (241 aa)
dapA4-Hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (289 aa)
asdAspartate-semialdehyde dehydrogenase, beta-type; Belongs to the aspartate-semialdehyde dehydrogenase family. (330 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (260 aa)
thrAAspartate kinase, monofunctional class; Belongs to the aspartokinase family. (400 aa)
lysADiaminopimelate decarboxylase LysA; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (418 aa)
pgmPhosphoglucomutase. (543 aa)
mgsAMethylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (122 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (431 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (510 aa)
galM1Aldose 1-epimerase. (301 aa)
Aocu_11520Kinase, PfkB family. (340 aa)
kdgKPutative 2-dehydro-3-deoxygluconokinase. (326 aa)
eda4-Hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxyphosphogluconate aldolase. (213 aa)
galM2Aldose 1-epimerase. (319 aa)
Aocu_12000FAD-linked oxidase. (465 aa)
rpeRibulose-5-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (210 aa)
adhE2Bifunctional aldehyde/alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (862 aa)
pgl6-phosphogluconolactonase. (307 aa)
rpiBRibose 5-phosphate isomerase B. (148 aa)
Aocu_12930Glyoxalase/fosfomycin resistance/dioxygenase domain-containing protein. (280 aa)
tktTransketolase; Belongs to the transketolase family. (651 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (411 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (278 aa)
fhsFormate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (528 aa)
pdlBPyruvate formate-lyase. (756 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (322 aa)
pduLSimilar to propanediol utilisation protein PduL; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (196 aa)
fbaFructose-1,6-bisphosphate aldolase, class II. (287 aa)
Aocu_14550Phosphoesterase. (313 aa)
Your Current Organism:
Acholeplasma oculi
NCBI taxonomy Id: 35623
Other names: A. oculi, ATCC 27350, Acholeplasma oculusi, NCTC 10150
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