STRINGSTRING
AKE40740.1 AKE40740.1 folK folK AKE40795.1 AKE40795.1 AKE40859.1 AKE40859.1 mdh mdh aspA aspA ppc ppc aroQ aroQ aroB aroB aroK aroK aroC aroC aroE aroE dapF dapF dapA dapA dapB dapB gdh gdh amiB amiB aroG aroG lysA lysA AKE41689.1 AKE41689.1 folP2 folP2 dapE dapE dapD dapD dapD-2 dapD-2 fumC fumC citE citE AKE41859.1 AKE41859.1 dapA1 dapA1 lysC lysC asd asd AKE40673.1 AKE40673.1 aroA aroA tpdA tpdA folP1 folP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKE40740.1Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (117 aa)
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase. (148 aa)
AKE40795.1Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. (307 aa)
AKE40859.1Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family. (276 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (323 aa)
aspAAspartate ammonia-lyase. (504 aa)
ppcPhosphoenolpyruvate carboxylase, type 1; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (922 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (146 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (358 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (233 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (402 aa)
aroEShikimate-5-dehydrogenase, fungal AROM-type. (278 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (284 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (301 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (246 aa)
gdhGlutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (447 aa)
amiBAmidohydrolase. (415 aa)
aroG3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Belongs to the class-II DAHP synthase family. (473 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (441 aa)
AKE41689.1Shikimate 5-dehydrogenase. (269 aa)
folP2Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (288 aa)
dapESuccinyldiaminopimelate desuccinylase. (363 aa)
dapDTetrahydrodipicolinate N-succinyltransferase. (303 aa)
dapD-22,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (325 aa)
fumCFumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)
citECitrate lyase beta subunit; Belongs to the HpcH/HpaI aldolase family. (271 aa)
AKE41859.1Chorismate mutase. (101 aa)
dapA1Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family. (311 aa)
lysCAspartate kinase; Belongs to the aspartokinase family. (421 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (343 aa)
AKE40673.1Amidohydrolase. (403 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (425 aa)
tpdAAcetylornithine deacetylase/succinyldiaminopimelate desuccinylase-like deacylase. (447 aa)
folP1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (263 aa)
Your Current Organism:
Corynebacterium kutscheri
NCBI taxonomy Id: 35755
Other names: ATCC 15677, Bacillus pesudotuberculosis murium, Bacterium kutscheri, C. kutscheri, CCUG 27535, CIP 103423, Corynebacterium murium, DSM 20755, IFO 15288, JCM 9385, NBRC 15288, NCTC 11138
Server load: low (32%) [HD]