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Cphy_0021 Cphy_0021 rpsG rpsG hpf hpf rpmE rpmE rpmI rpmI rpmF rpmF rpsP rpsP Cphy_2425 Cphy_2425 rpmA rpmA rplU rplU rpsU rpsU rpsB rpsB rpsO rpsO Cphy_2775 Cphy_2775 rpmB rpmB rpsI rpsI rplM rplM rpsK rpsK rpsM rpsM rpmJ rpmJ rplO rplO rpmD rpmD rpsE rpsE rplR rplR rpsH rpsH Cphy_3654 Cphy_3654 rplE rplE rplX rplX rplN rplN rpsQ rpsQ rpmC rpmC rpsC rpsC rpsS rpsS rplB rplB rplW rplW rplC rplC rpsJ rpsJ rplL rplL rplJ rplJ rplA rplA rplK rplK rpmG rpmG rpsR rpsR rpsF rpsF rpmH rpmH
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Cphy_0021PFAM: RNA binding S1 domain protein; KEGG: cno:NT01CX_1373 RpsA. (303 aa)
rpsGRibosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
hpfSigma 54 modulation protein/ribosomal protein S30EA; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. (178 aa)
rpmERibosomal protein L31; Binds the 23S rRNA. (70 aa)
rpmIPFAM: ribosomal protein L35; KEGG: cbf:CLI_3194 ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family. (65 aa)
rpmFTIGRFAM: ribosomal protein L32; PFAM: ribosomal L32p protein; KEGG: chy:CHY_1453 ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. (61 aa)
rpsPPFAM: ribosomal protein S16; KEGG: cno:NT01CX_2212 ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. (81 aa)
Cphy_2425KEGG: dsy:DSY0156 hypothetical protein. (145 aa)
rpmAPFAM: ribosomal protein L27; KEGG: cpr:CPR_2095 ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. (95 aa)
rplURibosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (102 aa)
rpsUPFAM: ribosomal protein S21; KEGG: cpr:CPR_1995 ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family. (58 aa)
rpsBPFAM: ribosomal protein S2; KEGG: bld:BLi01870 ribosomal protein S2; RBL02224; Belongs to the universal ribosomal protein uS2 family. (246 aa)
rpsORibosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (88 aa)
Cphy_2775PFAM: ribosomal protein L7Ae/L30e/S12e/Gadd45; KEGG: cdf:CD1308 putative ribosomal protein. (115 aa)
rpmBPFAM: ribosomal protein L28; KEGG: swo:Swol_0757 50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family. (65 aa)
rpsIPFAM: ribosomal protein S9; KEGG: ctc:CTC02571 SSU ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (130 aa)
rplMRibosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (144 aa)
rpsKRibosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (132 aa)
rpsMRibosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (122 aa)
rpmJPFAM: ribosomal protein L36; KEGG: csc:Csac_2263 ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. (37 aa)
rplORibosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (146 aa)
rpmDPFAM: ribosomal protein L30; KEGG: spd:SPD_0211 ribosomal protein L30. (60 aa)
rpsERibosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (168 aa)
rplRRibosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (122 aa)
rpsHRibosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (133 aa)
Cphy_3654PFAM: ribosomal protein S14; KEGG: amt:Amet_4465 ribosomal protein S14. (56 aa)
rplERibosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa)
rplXRibosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (105 aa)
rplNRibosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rpsQRibosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (85 aa)
rpmCPFAM: ribosomal protein L29; KEGG: rsq:Rsph17025_2526 ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (69 aa)
rpsCRibosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (219 aa)
rpsSRibosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa)
rplBRibosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (281 aa)
rplWRibosomal protein L25/L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (99 aa)
rplCRibosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (211 aa)
rpsJRibosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (105 aa)
rplLRibosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (120 aa)
rplJRibosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (164 aa)
rplARibosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (230 aa)
rplKRibosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (142 aa)
rpmGPFAM: ribosomal protein L33; KEGG: amt:Amet_4493 ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (49 aa)
rpsRRibosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (91 aa)
rpsFRibosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (95 aa)
rpmHPFAM: ribosomal protein L34; KEGG: lre:Lreu_1944 ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. (44 aa)
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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