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secY secY Cphy_0017 Cphy_0017 Cphy_0018 Cphy_0018 Cphy_0037 Cphy_0037 Cphy_0099 Cphy_0099 Cphy_0100 Cphy_0100 Cphy_0149 Cphy_0149 Cphy_0199 Cphy_0199 Cphy_0205 Cphy_0205 Cphy_0254 Cphy_0254 secA secA Cphy_0321 Cphy_0321 Cphy_0337 Cphy_0337 Cphy_0399 Cphy_0399 Cphy_0431 Cphy_0431 Cphy_0432 Cphy_0432 Cphy_0433 Cphy_0433 Cphy_0442 Cphy_0442 Cphy_0443 Cphy_0443 Cphy_0454 Cphy_0454 Cphy_0463 Cphy_0463 Cphy_0666 Cphy_0666 secF secF Cphy_0735 Cphy_0735 Cphy_0739 Cphy_0739 Cphy_0805 Cphy_0805 Cphy_0806 Cphy_0806 Cphy_0807 Cphy_0807 Cphy_0812 Cphy_0812 Cphy_0813 Cphy_0813 Cphy_0814 Cphy_0814 Cphy_0855 Cphy_0855 Cphy_0856 Cphy_0856 Cphy_1040 Cphy_1040 Cphy_1055 Cphy_1055 Cphy_1056 Cphy_1056 Cphy_1068 Cphy_1068 Cphy_1237 Cphy_1237 Cphy_1238 Cphy_1238 msrA msrA Cphy_1503 Cphy_1503 Cphy_1569 Cphy_1569 Cphy_1570 Cphy_1570 Cphy_1591 Cphy_1591 Cphy_1667 Cphy_1667 Cphy_1681 Cphy_1681 Cphy_1682 Cphy_1682 Cphy_1811 Cphy_1811 Cphy_1851 Cphy_1851 Cphy_1995 Cphy_1995 Cphy_1996 Cphy_1996 Cphy_1997 Cphy_1997 Cphy_2135 Cphy_2135 Cphy_2137 Cphy_2137 Cphy_2155 Cphy_2155 Cphy_2175 Cphy_2175 Cphy_2200 Cphy_2200 Cphy_2201 Cphy_2201 Cphy_2226 Cphy_2226 Cphy_2429 Cphy_2429 Cphy_2430 Cphy_2430 Cphy_2834 Cphy_2834 Cphy_2867 Cphy_2867 rpoZ rpoZ Cphy_3003 Cphy_3003 Cphy_3066 Cphy_3066 Cphy_3067 Cphy_3067 Cphy_3104 Cphy_3104 Cphy_3106 Cphy_3106 Cphy_3107 Cphy_3107 Cphy_3115 Cphy_3115 Cphy_3116 Cphy_3116 Cphy_3218 Cphy_3218 Cphy_3285 Cphy_3285 Cphy_3367 Cphy_3367 Cphy_3368 Cphy_3368 Cphy_3379 Cphy_3379 Cphy_3380 Cphy_3380 Cphy_3393 Cphy_3393 rpoA rpoA rpoC rpoC rpoB rpoB secE secE Cphy_3746 Cphy_3746 Cphy_3781 Cphy_3781 Cphy_3782 Cphy_3782 Cphy_3919 Cphy_3919
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
secYPreprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (442 aa)
Cphy_0017PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: cpe:CPE1525 probable ABC transporter. (593 aa)
Cphy_0018PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: cbe:Cbei_2793 ABC transporter related. (581 aa)
Cphy_0037Hypothetical protein. (304 aa)
Cphy_0099PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: cdf:CD2818 ABC transporter, ATP-binding/permease protein. (575 aa)
Cphy_0100PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: cdf:CD2817 ABC transporter, ATP-binding/permease protein. (584 aa)
Cphy_0149PFAM: regulatory protein AsnC/Lrp family; KEGG: csc:Csac_1961 putative transcriptional regulator, AsnC family. (160 aa)
Cphy_0199PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: ctc:CTC01479 hypothetical protein. (177 aa)
Cphy_0205Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (223 aa)
Cphy_0254TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; HI0933 family protein; KEGG: tte:TTE2220 thioredoxin reductase. (308 aa)
secAPreprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (858 aa)
Cphy_0321PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ctc:CTC02435 sarcosine oxidase alpha subunit. (420 aa)
Cphy_0337PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: ctc:CTC01811 multidrug resistance ABC transporter ATP-binding and permease protein. (582 aa)
Cphy_0399PFAM: GCN5-related N-acetyltransferase; KEGG: cpf:CPF_1025 acetyltransferase, GNAT family. (388 aa)
Cphy_0431PFAM: extracellular solute-binding protein family 5; KEGG: fnu:FN1359 dipeptide-binding protein. (522 aa)
Cphy_0432PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rle:RL0227 putative transmembrane component of ABC transporter. (313 aa)
Cphy_0433PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: oih:OB3067 oligopeptide ABC transporter permease. (262 aa)
Cphy_0442PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: tte:TTE0836 ABC-type multidrug/protein/lipid transport system, ATPase component. (618 aa)
Cphy_0443PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: tte:TTE0835 ABC-type multidrug/protein/lipid transport system, ATPase component. (588 aa)
Cphy_0454KEGG: dsy:DSY4222 hypothetical protein. (107 aa)
Cphy_0463Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (215 aa)
Cphy_0666Hypothetical protein; KEGG: bvu:BVU_0177 glycoside hydrolase family 28. (897 aa)
secFProtein-export membrane protein, SecD/SecF family; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. (734 aa)
Cphy_0735Redoxin domain protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; Thioredoxin domain; KEGG: dsy:DSY1195 hypothetical protein. (211 aa)
Cphy_0739TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: dsy:DSY2429 hypothetical protein; Belongs to the thioredoxin family. (104 aa)
Cphy_0805PFAM: extracellular solute-binding protein family 5; KEGG: bcy:Bcer98_0219 extracellular solute-binding protein family 5. (825 aa)
Cphy_0806PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: cac:CAC0177 oligopeptide transport permease protein. (334 aa)
Cphy_0807PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: tte:TTE2524 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components. (349 aa)
Cphy_0812PFAM: extracellular solute-binding protein family 5; KEGG: tte:TTE2522 ABC-type dipeptide/oligopeptide/nickel transport systems, periplasmic components. (793 aa)
Cphy_0813PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: cac:CAC0177 oligopeptide transport permease protein. (328 aa)
Cphy_0814PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: cpr:CPR_2256 oligopeptide ABC transporter, permease component. (603 aa)
Cphy_0855PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: ckl:CKL_1784 predicted transport protein. (755 aa)
Cphy_0856PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: tte:TTE2513 ABC-type multidrug/protein/lipid transport system, ATPase component. (626 aa)
Cphy_1040PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: lac:LBA0722 protein-tyrosine phosphatase. (155 aa)
Cphy_1055PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: tte:TTE2769 ABC-type multidrug/protein/lipid transport system, ATPase component. (554 aa)
Cphy_1056PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: tte:TTE2769 ABC-type multidrug/protein/lipid transport system, ATPase component. (546 aa)
Cphy_1068ABC-type phosphate transport system periplasmic component-like protein; KEGG: dsy:DSY3435 hypothetical protein. (835 aa)
Cphy_1237PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: cth:Cthe_3147 ABC transporter related protein. (583 aa)
Cphy_1238PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: cth:Cthe_3148 ABC transporter related protein. (631 aa)
msrAPeptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (166 aa)
Cphy_1503Thioredoxin-disulfide reductase; PFAM: glucose-inhibited division protein A; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cth:Cthe_1945 thioredoxin-disulfide reductase. (292 aa)
Cphy_1569PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: cdf:CD1822 putative thiol peroxidase (bacterioferritin comigratory protein). (150 aa)
Cphy_1570Ferritin Dps family protein; Iron-storage protein. (170 aa)
Cphy_1591PFAM: major facilitator superfamily MFS_1; KEGG: tme:Tmel_0369 major facilitator superfamily MFS_1. (414 aa)
Cphy_1667TIGRFAM: phosphate binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: csc:Csac_1610 phosphate binding protein. (279 aa)
Cphy_1681PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: dsy:DSY1261 hypothetical protein. (585 aa)
Cphy_1682PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: dsy:DSY1260 hypothetical protein. (613 aa)
Cphy_1811PFAM: regulatory protein AsnC/Lrp family; KEGG: bld:BLi03851 YwrC. (152 aa)
Cphy_1851Cytochrome c biogenesis protein transmembrane region; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; electron transport protein SCO1/SenC; cytochrome c biogenesis protein transmembrane region; Redoxin domain protein; Thioredoxin domain; KEGG: cpr:CPR_0721 cytochrome c biogenesis protein transmembrane region family. (409 aa)
Cphy_1995KEGG: mac:MA4292 cell surface protein. (691 aa)
Cphy_1996PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: dsy:DSY1865 hypothetical protein. (305 aa)
Cphy_1997PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: dsy:DSY1864 hypothetical protein. (348 aa)
Cphy_2135PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: spd:SPD_1621 ABC transporter, ATP-binding/permease protein. (583 aa)
Cphy_2137ABC-type multidrug transport system ATPase and permease components-like protein; KEGG: lsa:LSA1148 putative multidrug ABC exporter, ATP-binding and membrane-spanning/permease subunits. (250 aa)
Cphy_2155PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: cbe:Cbei_2111 protein tyrosine phosphatase. (136 aa)
Cphy_2175KEGG: amt:Amet_4677 hypothetical protein. (267 aa)
Cphy_2200PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: tde:TDE1062 ABC transporter, ATP-binding protein, HlyB family. (626 aa)
Cphy_2201PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: tde:TDE1061 ABC transporter, ATP-binding/permease protein, HlyB family. (618 aa)
Cphy_2226KEGG: tte:TTE1718 thiol-disulfide isomerase and thioredoxins. (108 aa)
Cphy_2429PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: cth:Cthe_0397 ABC transporter related protein. (619 aa)
Cphy_2430PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: cth:Cthe_0396 ABC transporter related protein. (575 aa)
Cphy_2834TIGRFAM: phosphate binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: drm:Dred_2106 phosphate binding protein. (307 aa)
Cphy_2867Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (81 aa)
rpoZDNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (82 aa)
Cphy_3003PFAM: GCN5-related N-acetyltransferase; KEGG: drm:Dred_2229 hypothetical protein. (299 aa)
Cphy_3066PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: cpe:CPE0834 probable ABC transporter. (593 aa)
Cphy_3067PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: cpf:CPF_0829 ABC transporter, ATP-binding protein. (616 aa)
Cphy_3104PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; KEGG: spi:MGAS10750_Spy0250 oligopeptide transport ATP-binding protein OppF; Belongs to the ABC transporter superfamily. (352 aa)
Cphy_3106PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: spi:MGAS10750_Spy0248 oligopeptide transport system permease protein OppC. (324 aa)
Cphy_3107PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sae:NWMN_0856 oligopeptide transport system permease protein. (312 aa)
Cphy_3115PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: tde:TDE0028 ABC transporter, ATP-binding protein, HlyB family. (606 aa)
Cphy_3116PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: cpr:CPR_0817 antibiotic ABC transporter, ATP-binding protein. (610 aa)
Cphy_3218Major facilitator superfamily MFS_1; PFAM: Protein of unknown function DUF895, eukaryotic; major facilitator superfamily MFS_1; KEGG: ckl:CKL_0592 predicted transporter protein. (385 aa)
Cphy_3285Hypothetical protein. (562 aa)
Cphy_3367Cellulase; PFAM: glycoside hydrolase family 9; type 3a cellulose-binding domain protein; protein of unknown function DUF291; KEGG: csc:Csac_1076 glycoside hydrolase, family 48. (985 aa)
Cphy_3368PFAM: glycoside hydrolase family 48; type 3a cellulose-binding domain protein; protein of unknown function DUF291; KEGG: csc:Csac_1076 glycoside hydrolase, family 48. (919 aa)
Cphy_3379PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: cno:NT01CX_1825 ABC-type multidrug/protein/lipid transport system, ATPase. (646 aa)
Cphy_3380PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: cac:CAC2393 uncharacterized ABC transporter, ATPase component. (573 aa)
Cphy_3393PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: tde:TDE0135 pyridine nucleotide-disulphide oxidoreductase family protein. (440 aa)
rpoADNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (319 aa)
rpoCDNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1255 aa)
rpoBDNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1278 aa)
secEPreprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (76 aa)
Cphy_3746PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: sha:SH0920 putative low molecular weight protein-tyrosine-phosphatase. (151 aa)
Cphy_3781PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: lwe:lwe0099 ABC transporter, ATP-binding/permease protein. (588 aa)
Cphy_3782PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: lwe:lwe0098 ABC transporter, ATP-binding/permease protein. (594 aa)
Cphy_3919TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: sat:SYN_00045 thioredoxin; Belongs to the thioredoxin family. (103 aa)
Your Current Organism:
Lachnoclostridium phytofermentans
NCBI taxonomy Id: 357809
Other names: Clostridium phytofermentans ISDg, L. phytofermentans ISDg, Lachnoclostridium phytofermentans ISDg
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