76 items (Bordetella holmesii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	AOB34916.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (608 aa)
	AOB37084.1	AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
	BBB42_17135	DNA protecting protein DprA; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
	kynU	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (412 aa)
	AOB37047.1	Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
	AOB37043.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
	AOB36965.1	Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
	AOB36905.1	FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)
	AOB36877.1	Mandelate racemase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (391 aa)
	AOB36836.1	Nopaline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
	AOB36834.1	FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
	AOB36801.1	2-pyrone-4,6-dicarboxylate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
	AOB36799.1	PrpF protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
	ligK	4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
	thpD	Ectoine hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
	AOB36693.1	Amino acid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa)
	AOB36594.1	DNA alkylation response protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (558 aa)
	gcvT	Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (366 aa)
	gcvH	Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (125 aa)
	gcvP	Glycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (957 aa)
	fahA	Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
	hmgA	LysR family transcriptional regulator; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (432 aa)
	AOB36487.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (129 aa)
	AOB36486.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (147 aa)
	AOB36455.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
	AOB36454.1	hydroxymethylglutaryl-CoA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family. (311 aa)
	AOB36312.1	Putative methylaconitate Delta-isomerase PrpF; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
	AOB36224.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
	AOB36221.1	Dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (169 aa)
	AOB36062.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
	AOB36058.1	Aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (266 aa)
	AOB35897.1	Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
	AOB35853.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
	AOB35732.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
	AOB35694.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (108 aa)
	AOB35693.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (272 aa)
	hutG_1	Formimidoylglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family. (315 aa)
	AOB35614.1	Serine/threonine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
	AOB37312.1	Threonine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (169 aa)
	AOB35574.1	Fumarylacetoacetate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
	AOB35566.1	SlyX protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (72 aa)
	coaBC	Phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (403 aa)
	AOB35464.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
	AOB37300.1	5-carboxymethyl-2-hydroxymuconate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
	AOB35392.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
	kynB	Arylformamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. (209 aa)
	kynA	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (279 aa)
	AOB35243.1	Metal-activated pyridoxal enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (514 aa)
	AOB35176.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (776 aa)
	AOB35174.1	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (652 aa)
	AOB35172.1	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (794 aa)
	AOB35165.1	Class III aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
	AOB35164.1	D-amino acid dehydrogenase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (415 aa)
	putA	Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1268 aa)
	garL	2-dehydro-3-deoxyglucarate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (256 aa)
	AOB35021.1	N-formylglutamate amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
	paaD	Phenylacetic acid degradation protein PaaD; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
	paaJ	phenylacetate-CoA oxygenase subunit PaaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
	paaI	phenylacetate-CoA oxygenase subunit PaaI; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
	paaH	1,2-phenylacetyl-CoA epoxidase subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa)
	paaG	1,2-phenylacetyl-CoA epoxidase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
	paaX	Phenylacetic acid degradation operon negative regulatory protein PaaX; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
	sucB	Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (407 aa)
	AOB34798.1	Thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa)
	anmK	anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (375 aa)
	boxB	benzoyl-CoA oxygenase subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
	boxC	benzoyl-CoA-dihydrodiol lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (547 aa)
	AOB34475.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
	AOB34341.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (382 aa)
	AOB37240.1	FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (502 aa)
	AOB34250.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (376 aa)
	AOB34228.1	L-rhamnonate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (390 aa)
	AOB34172.1	Histidine triad nucleotide-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (122 aa)
	AOB34141.1	Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (106 aa)
	AOB34114.1	isovaleryl-CoA dehydrogenase; Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
	AOB34109.1	Alanine racemase; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)

Your Current Organism:

Bordetella holmesii

NCBI taxonomy Id: 35814
Other names: ATCC 51541, B. holmesii, CCUG 34073, CDC F5101, CDC nonoxidizer group 2 (NO-2), CIP 104394, DSM 13416, LMG 15945, LMG:15945, NCTC 12912

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AOB34114.1	AOB35172.1	BBB42_00540	BBB42_06450	isovaleryl-CoA dehydrogenase; Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.770
AOB34114.1	AOB35174.1	BBB42_00540	BBB42_06460	isovaleryl-CoA dehydrogenase; Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.976
AOB34114.1	AOB36221.1	BBB42_00540	BBB42_12355	isovaleryl-CoA dehydrogenase; Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.431
AOB34114.1	AOB36454.1	BBB42_00540	BBB42_13670	isovaleryl-CoA dehydrogenase; Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	hydroxymethylglutaryl-CoA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.474
AOB34114.1	BBB42_17135	BBB42_00540	BBB42_17135	isovaleryl-CoA dehydrogenase; Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	DNA protecting protein DprA; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.606
AOB34114.1	boxC	BBB42_00540	BBB42_02875	isovaleryl-CoA dehydrogenase; Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.	benzoyl-CoA-dihydrodiol lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.464
AOB34250.1	AOB35172.1	BBB42_01300	BBB42_06450	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.770
AOB34250.1	AOB35174.1	BBB42_01300	BBB42_06460	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.770
AOB34250.1	AOB36221.1	BBB42_01300	BBB42_12355	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.431
AOB34250.1	boxC	BBB42_01300	BBB42_02875	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	benzoyl-CoA-dihydrodiol lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.720
AOB34341.1	AOB35172.1	BBB42_01800	BBB42_06450	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.804
AOB34341.1	AOB35174.1	BBB42_01800	BBB42_06460	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.976
AOB34341.1	AOB36221.1	BBB42_01800	BBB42_12355	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.431
AOB34341.1	boxC	BBB42_01800	BBB42_02875	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	benzoyl-CoA-dihydrodiol lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.720
AOB34475.1	AOB35172.1	BBB42_02580	BBB42_06450	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.770
AOB34475.1	AOB35174.1	BBB42_02580	BBB42_06460	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.916
AOB34475.1	AOB35392.1	BBB42_02580	BBB42_07695	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.917
AOB34475.1	AOB35694.1	BBB42_02580	BBB42_09415	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.899
AOB34475.1	AOB36221.1	BBB42_02580	BBB42_12355	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.431
AOB34475.1	boxC	BBB42_02580	BBB42_02875	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	benzoyl-CoA-dihydrodiol lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.720

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